A symptom of the central vein in various diseases and protocols of MRI examination

Belov S.E.; Boyko A.N.

doi:https://doi.org/10.17116/jnevro202212207219

Belov S.E.

Pirogov Russian National Research Medical University

Boyko A.N.

Pirogov Russian National Research Medical University;
Federal Center of Brain Research and Neurotechnologies of the Federal Medical Biological Agency

SPIN RSCI: 9921-9109
Scopus AuthorID: 7102247663
ORCID: 0000-0002-2975-4151

A symptom of the central vein in various diseases and protocols of MRI examination

Authors:

Belov S.E., Boyko A.N.

More about the authors

Journal: S.S. Korsakov Journal of Neurology and Psychiatry. 2022;122(7‑2): 19‑26

DOI: 10.17116/jnevro202212207219

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To cite this article:

Belov SE, Boyko AN. A symptom of the central vein in various diseases and protocols of MRI examination. S.S. Korsakov Journal of Neurology and Psychiatry. 2022;122(7‑2):19‑26. (In Russ.)
https://doi.org/10.17116/jnevro202212207219

Подписка 2026 Журнал неврологии и психиатрии им. С.С. Корсакова. Спецвыпуски (S.S. Korsakov Journal of Neurology and Psychiatry (special issues))

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Abstract:

This article reviews the literature concerning the possibility of using magnetic resonance imaging (MRI) with different field strengths to detect the central vein sign (CVS). CVS is a relatively new and promising symptom of multiple sclerosis (MS). This symptom is a parenchymal vein visualized with the help of special MRI modes, which is localized in the focus of demyelination. Studies show that CVS has a high sensitivity and specificity in the diagnosis of MS, allowing the differentiation from other demyelinating, vascular, systemic diseases. However, most studies in this direction have been done using different MR-sequences and on tomographs with different field strengths, so the purpose of this review is to summarize and compare the results of various studies, which may be of practical benefit to clinicians.

Keywords:

multiple sclerosis

central vein sign

MRI

diagnosis

differential diagnosis

demyelinating diseases

small vessel disease

biomarker

Authors:

Belov S.E.

Pirogov Russian National Research Medical University

Boyko A.N.

Pirogov Russian National Research Medical University;
Federal Center of Brain Research and Neurotechnologies of the Federal Medical Biological Agency

SPIN RSCI: 9921-9109
Scopus AuthorID: 7102247663
ORCID: 0000-0002-2975-4151

Received:

06.05.2022

Accepted:

17.05.2022

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References:

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