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Zakharov A.V.

Samara State Medical University

Kalinin V.A.

Samara State Medical University

Khivintseva E.V.

Samara State Medical University

Sleep disorders in synucleinopathy

Authors:

Zakharov A.V., Kalinin V.A., Khivintseva E.V.

More about the authors

Journal: S.S. Korsakov Journal of Neurology and Psychiatry. 2021;121(4‑2): 98‑102

DOI: 10.17116/jnevro202112104298

Read: 2218 times

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Table of contents

SLEEP DISORDERS IN SYNUCLEINOPATHY
SLEEP DISORDERS IN SYNUCLEINOPATHY

To cite this article:

Zakharov AV, Kalinin VA, Khivintseva EV. Sleep disorders in synucleinopathy. S.S. Korsakov Journal of Neurology and Psychiatry. 2021;121(4‑2):98‑102. (In Russ.)
https://doi.org/10.17116/jnevro202112104298

Подписка 2026 Журнал неврологии и психиатрии им. С.С. Корсакова. Спецвыпуски (S.S. Korsakov Journal of Neurology and Psychiatry (special issues))
 
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Abstract:

The article highlights the current state of the problem of sleep disorders in various neurodegenerative diseases. The clinical picture and diagnosis of these disorders are described in detail. Separately, the emphasis is made on the mechanisms underlying development of these disorders and their features in various forms of synucleinopathies. The mediator and physiological changes that underlie sleep disorders in various nosological units of synucleinopathies are discussed in detail. The current attitude to certain sleep disorders as predictors of neurodegenerative diseases is evaluated. The role of the glymphatic system in the development of these disorders is considered. Also, modern therapeutic strategies for sleep disorders in neurodegenerative diseases are discussed.

Keywords:

sleep disturbance
synucleinopathies
neurodegeneration
pathogenesis

Authors:

Zakharov A.V.

Samara State Medical University

Kalinin V.A.

Samara State Medical University

Khivintseva E.V.

Samara State Medical University

Received:

19.02.2021

Accepted:

10.03.2021

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