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Iakushina T.I.

Belova Iu.A.

Moskovskiĭ oblastnoĭ nauchno-issledovatel'skiĭ klinicheskiĭ institut im. M.F. Vladimirskogo

Cases of pregnancy in patients with aggressive multiple sclerosis treated with natalizumab

Authors:

Iakushina T.I., Belova Iu.A.

More about the authors

Journal: S.S. Korsakov Journal of Neurology and Psychiatry. 2019;119(2‑2): 94‑97

DOI: 10.17116/jnevro20191192294

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Table of contents

CASES OF PREGNANCY IN PATIENTS WITH AGGRESSIVE MULTIPLE SCLEROSIS TREATED WITH NATALIZUMAB
CASES OF PREGNANCY IN PATIENTS WITH AGGRESSIVE MULTIPLE SCLEROSIS TREATED WITH NATALIZUMAB

To cite this article:

Iakushina TI, Belova IuA. Cases of pregnancy in patients with aggressive multiple sclerosis treated with natalizumab. S.S. Korsakov Journal of Neurology and Psychiatry. 2019;119(2‑2):94‑97. (In Russ.)
https://doi.org/10.17116/jnevro20191192294

Подписка 2026 Журнал неврологии и психиатрии им. С.С. Корсакова. Спецвыпуски (S.S. Korsakov Journal of Neurology and Psychiatry (special issues))
 
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Abstract:

The authors consider the issues concerning planning of pregnancy in patients with multiple sclerosis receiving pathogenetic and immunomodulatory therapy and provide descriptions of cases of pregnancy in patients with aggressively multiple sclerosis occurred during the treatment with natalizumab.

Keywords:

multiple sclerosis
aggressive multiple sclerosis
multiple sclerosis and pregnancy
natalizumab

Authors:

Iakushina T.I.

Belova Iu.A.

Moskovskiĭ oblastnoĭ nauchno-issledovatel'skiĭ klinicheskiĭ institut im. M.F. Vladimirskogo

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References:

  1. Yakushina TI, Kotov SV, Yakushin MA. Analysis of the course of pregnancy, delivery and postpartum period in women with multiple sclerosis. Al’manakh Klinicheskoi Meditsin. 2015;39:82-88. (In Russ.) https://doi.org/10.18786/2072-0505-2015-39-82-89
  2. Babenko LA, Malkova NA. Rasseyannyi skleroz: beremennost’ I terapiya preparatami, izmenyayushchimi techenie rasseyannogo skleroza. Materialy X Vserossiiskogo s’ezda nevrologov s mezhdunarodnym uchastiem; 2012. (In Russ.)
  3. Kotov SV, Yakushina TI. Rasseyannyi skleroz i beremennost’. Osobennosti techeniya beremennosti, rodov I poslerodovogo perioda u zhenshchin, stradayushchikh rasseyannym sklerozom. Rezul’taty nablyudenii za patsientami dannoi gruppy v Moskovskoi oblasti. Russian Medical Journal. 2015;12(23):720-724. (In Russ.)
  4. Shmidt TE, Yakhno NN. Rasseyannyi skleroz. Rukovodstvo dlya vrachei. 2-e izd. M.: MEDpress-inform; 2010. (In Russ.)
  5. Popova EV, Kukel TM, Muravin AI, Boyko AN, Murashko AV, Gusev EI. Pregnancy and deliveryin women with multiple sclerosis: a retrospective analysi. Zhurnal Nevrologii i Psikhiatrii im. S.S. Korsakova. 2013;113(10-2):52-56. (In Russ.)
  6. Demina TN, Mailyan EF, Gyul’mamedova ID, Gyul’mamedov VA. Sovremennye vzglyady na immunologiyu gestatsionnogo protsessa. Reproduktivnoe Zdorov’e Zhenshchiny. 2003;1:18-22. (In Russ.)
  7. Dobrodeev KT, Usynin MV, Moskovskaya NB. Immunnaya sistema pri fiziologicheskom techenii beremennosti. Immunologiya. 2001;1:355. (In Russ.)
  8. Devonshire V, Duguette P, Dwosh E, Guimomd C, Sadovnick AD. The immune system and hormones: review and relevance to pregnancy and contraception in women with MS. Int MSJ. 2003;10(2):45-50.
  9. Gilmore W, Arias M, Stroud N, Stek A, McCarthy KA, Correale J. Preliminary studies of cytokine secretion patterns associated with pregnancy in MS patients. J Neurol Sci. 2004;224:69-76. https://doi.org/10.1016/j.jns.2004.06.011
  10. Voskuhl R. Sex hormones and other pregnancy-related factors with therapeutic potential in multiple sclerosis. In: Cohen D., Rudick R., eds. Multiple Sclerosis Therapeutics. London: Martin Dunitz Ltd; 2003. https://doi.org/10.1017/cbo9781139023986.046
  11. Kotov SV, Yakushina TI, Lizhdvoi VYu. Long-term comparative studying efficiency of drugs that change the course of multiple sclerosise. Al’manakh Klinicheskoi Meditsin. 2011;25:37-40. (In Russ.)
  12. Zakharova MN, Lysogorskaia EV, Trushnikova TN, Zhelnin AV. The case-report of progressive multifocal leukoencephalopathy in a patient with multiple sclerosis treated with natalizumab. Zhurnal Nevrologii i Psikhiatrii im. S.S. Korsakova. 2018;118(8):107-109. (In Russ.) https://doi.org/10.17116/jnevro2018118082107
  13. Haghikia A, Langer-Gould A, Rellensmann G, Haghikia A, Langer-Gould A, Rellensmann G, Schneider H, Tenenbaum T, Elias-Hamp B, Menck S, Zimmermann J, Herbstritt S, Marziniak M, Kümpfel T, Mein I, Plavina T, Gold R, Hellwig K. Natalizumab use during the third trimester of pregnancy. JAMA Neurol. 2014;71(7):891-895. https://doi.org/10.1001/jamaneurol.2014.209
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