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Krylov V.V.

FGBU MRNTs Minzdrava Rossii, Obninsk

Guekht A.B.

Moscow Research and Clinical Centre for Neuropsychiatry;
Pirogov Russian National Research Medical University

Trifonov I.S.

A.I. Evdokimov Moscow Medical University, Moscow, Russian Federation

Lebedeva A.V.

FGBU "Federal'nyĭ nauchnyĭ tsentr transplantologii i iskusstvennykh organov im. akad. V.I. Shumakova" Minzdrava Rossii, Moskva

Kaĭmovskiĭ I.L.

Gorodskaia klinicheskaia bol'nitsa # 12, Moskva

Sinkin M.V.

N.V. Sklifosovsky First Aid Scientific Research Institute, Moscow, Russia

Grigorieva Е.V.

Federal State Budgetary Institution «Federal Center of Traumatology, Orthopedics and endoprosthesis replacement» of Ministry of Health of the Russian Federation, Cheboksary, Russia

Kutrovskaia N.Iu.

Moskovskiĭ gosudarstvennyĭ mediko-stomatologicheskiĭ universitet;
NII skoroĭ pomoshchi im. N.V. Sklifosovskogo, Moskva

Surgical treatment patients with drug-resistant unilateral MRI-positive temporal forms of epilepsy

Authors:

Krylov V.V., Guekht A.B., Trifonov I.S., Lebedeva A.V., Kaĭmovskiĭ I.L., Sinkin M.V., Grigorieva Е.V., Kutrovskaia N.Iu.

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Journal: S.S. Korsakov Journal of Neurology and Psychiatry. 2019;119(11‑2): 5‑10

DOI: 10.17116/jnevro20191191125

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Table of contents

SURGICAL TREATMENT PATIENTS WITH DRUG-RESISTANT UNILATERAL MRI-POSITIVE TEMPORAL FORMS OF EPILEPSY
SURGICAL TREATMENT PATIENTS WITH DRUG-RESISTANT UNILATERAL MRI-POSITIVE TEMPORAL FORMS OF EPILEPSY

To cite this article:

Krylov VV, Guekht AB, Trifonov IS, et al. . Surgical treatment patients with drug-resistant unilateral MRI-positive temporal forms of epilepsy. S.S. Korsakov Journal of Neurology and Psychiatry. 2019;119(11‑2):5‑10. (In Russ.)
https://doi.org/10.17116/jnevro20191191125

Подписка 2026 Журнал неврологии и психиатрии им. С.С. Корсакова. Спецвыпуски (S.S. Korsakov Journal of Neurology and Psychiatry (special issues))
МСФ на ЯМ
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Abstract:

Objective. To evaluate the results of surgical treatment of patients with unilateral MRI-positive temporal forms of drug-resistant epilepsy. Materials and methods. A prospective analysis of 50 patients with unilateral MRI-positive temporal forms of drug-resistant epilepsy, who had undergone resective surgery in the Scientific Research Institute of Emergency Medicine of N.V. Sklifosovsky (Moscow) and in University Clinic of Moscow State University of Medicine and Dentistry between 01.01.14 and 12.12.17, has been performed. MRI-positive temporal symptomatic epilepsy was identified in 79 (55%) patients. MRI results showed unilateral temporal epileptogenic lesions in 50 (67%) patients. These patients were assigned to medial frontal lobectomy. Results. 82% patients become «seizure free» 12 and 24 months after surgical treatment. In other cases, seizures become less frequent and severe. Conclusion. The results confirm the efficacy and safety of surgical treatment of drug-resistant MRI-positive temporal forms of epilepsy.

Keywords:

epilepsy
surgery
focal cortical dysplasia
sclerosis of the hippocampus

Authors:

Krylov V.V.

FGBU MRNTs Minzdrava Rossii, Obninsk

Guekht A.B.

Moscow Research and Clinical Centre for Neuropsychiatry;
Pirogov Russian National Research Medical University

Trifonov I.S.

A.I. Evdokimov Moscow Medical University, Moscow, Russian Federation

Lebedeva A.V.

FGBU "Federal'nyĭ nauchnyĭ tsentr transplantologii i iskusstvennykh organov im. akad. V.I. Shumakova" Minzdrava Rossii, Moskva

Kaĭmovskiĭ I.L.

Gorodskaia klinicheskaia bol'nitsa # 12, Moskva

Sinkin M.V.

N.V. Sklifosovsky First Aid Scientific Research Institute, Moscow, Russia

Grigorieva Е.V.

Federal State Budgetary Institution «Federal Center of Traumatology, Orthopedics and endoprosthesis replacement» of Ministry of Health of the Russian Federation, Cheboksary, Russia

Kutrovskaia N.Iu.

Moskovskiĭ gosudarstvennyĭ mediko-stomatologicheskiĭ universitet;
NII skoroĭ pomoshchi im. N.V. Sklifosovskogo, Moskva

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