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Kovalzon V.M.

Severtsov Institute of Ecology and Evolution of Russian Academy of Sciences, Moscow, Russia

Functional neurochemistry of sleep—waking cycle in pathogenesis of neurological diseases

Authors:

Kovalzon V.M.

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Journal: S.S. Korsakov Journal of Neurology and Psychiatry. 2017;117(4‑2): 5‑11

DOI: 10.17116/jnevro2017117425-11

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Table of contents

FUNCTIONAL NEUROCHEMISTRY OF SLEEP—WAKING CYCLE IN PATHOGENESIS OF NEUROLOGICAL DISEASES
FUNCTIONAL NEUROCHEMISTRY OF SLEEP—WAKING CYCLE IN PATHOGENESIS OF NEUROLOGICAL DISEASES

To cite this article:

Kovalzon VM. Functional neurochemistry of sleep—waking cycle in pathogenesis of neurological diseases. S.S. Korsakov Journal of Neurology and Psychiatry. 2017;117(4‑2):5‑11. (In Russ.)
https://doi.org/10.17116/jnevro2017117425-11

Подписка 2026 Журнал неврологии и психиатрии им. С.С. Корсакова. Спецвыпуски (S.S. Korsakov Journal of Neurology and Psychiatry (special issues))
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Abstract:

Novel experimental data concerning the function of the basic cerebral neuromediator systems which take part in arousal reactions and waking maintenance are regarding in the review.

Keywords:

sleep
sleep—waking cycle
neuromediators
disorders of wakefulness and sleep

Authors:

Kovalzon V.M.

Severtsov Institute of Ecology and Evolution of Russian Academy of Sciences, Moscow, Russia

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References:

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  3. Kovalzon VM. Neurophysiology and neurochemistry of sleep. In: Levin YaI, Poluektov MG, eds. Somnology and sleep medicine, Selected lectures. M.: Medforum; 2013. (In Russ.).
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  11. Kovalzon VM, Zavalko IM. The neurochemistry of the sleep—wakefulness cycle and Parkinson’s disease. Neurochemical Journal. 30(3):193-206. https://doi.org/10.7868/S1027813313030060
  12. Kovalzon VM. The role of Orexin/Hypocretin System of the Brain in the Regulation of Wakefulness and Sleep. Effective Pharmacotherapy. Neurology and Psychiatry. Special Issue «Sleep and Sleep Disorders-4». 2016;19:6-14. (In Russ.).
  13. Li S-B, Giardino WJ, de Lecea L. Hypocretins and Arousal. Curr Topics Behav Neurosci. 2016. https://doi.org/10.1007/7854_2016_58
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  15. Kovalzon VM, Strygin KN. Neurochemical mechanisms of the regulation of sleep and wakefulness: the role of histamine receptors blockers in the treatment of insomnia. Effective Pharmacotherapy. Neurology and Psychiatry. Special issue «Sleep and sleep disorders». 2913;12:8-15. (In Russ.).
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  19. Kovalzon VM, Zavalko IM, Dorokhov VB. Parkinson’s disease, dopaminergic system of the brain and sleep regulation. In: Ugrumov M.V., ed. Neurodegenerative diseases: from genome to the entire organisms. V.1. M.: Nauchnyi Mir; 2014. (In Russ.).
  20. Brown RE, Basheer R, McKenna JT, Strecker RE, McCarley RW. Control of sleep and wakefulness. Physiol Rev. 2012;92:1087-1187. https://doi.org/10.1152/physrev.00032.2
  21. Schwartz MD, Kilduff TS. The Neurobiology of Sleep and Wakefulness. Pyiatr Clin N Am. 2015;38(4):615-644. https://doi.org/10.1016/j.psc.2015.07.002
  22. Garcia-Rill E, Luster B, Mahaffey S, Bisagno V, Urbano FJ. Pedunculopontine arousal system physiology — Implications for insomnia. Sleep Science. 2015;8:92-99. https://doi.org/10.1016/j.slsci.2015.06.002
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  24. Xu M, Chung S, Zhang S, Zhong P, Ma C, Chang W-C, Weissbourd B, Sakai N, Luo L, Nishino S, Dan Y. Basal forebrain circuit for sleep-wake control. Nature Neuroscience. 2015;18:1641-1647. https://doi.org/10.1038/nn.4143
  25. Kaur S, Pedersen NP, Yokota S, Hur EE, Fuller PM, Lazarus M, Chamberlin NL, Saper CB. Glutamatergic Signaling from the Parabrachial Nucleus Plays a Critical Role in Hypercapnic Arousal. The Journal of Neuroscience. 2013;33(18):7627-7640. https://doi.org/10.1523/JNEUROSCI.0173-13.2013
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