The site of the Media Sphera Publishers contains materials intended solely for healthcare professionals.
By closing this message, you confirm that you are a certified medical professional or a student of a medical educational institution.

Login
EN
+7 (495) 482-4118
+7 (495) 482-4329
+8 800 250-18-12
  • (toll-free number for subscriptions)
    Mon-Fri from 10 a.m. to 6 p.m.

  • © 1998-2026
+7 (495) 482-43-29
EN
All journals
Journal
Year
Year
Search result: 0

Briukhov V.V.

Krotenkova I.A.

FGBU "Nauchnyĭ tsentr nevrologii" RAN, Moskva

Morozova S.N.

Research Center of Neurology, Russian Academy of Sciences, Moscow

Krotenkova M.V.

Nauchnyĭ tsentr nevrologii RAMN, Moskva

A current view on the MRI diagnosis of multiple sclerosis: an update of 2016 revised MRI criteria

Authors:

Briukhov V.V., Krotenkova I.A., Morozova S.N., Krotenkova M.V.

More about the authors

Journal: S.S. Korsakov Journal of Neurology and Psychiatry. 2017;117(2‑2): 66‑73

DOI: 10.17116/jnevro20171172266-73

Read: 10124 times

Download PDF (RU)
Contact the author
Table of contents

A CURRENT VIEW ON THE MRI DIAGNOSIS OF MULTIPLE SCLEROSIS: AN UPDATE OF 2016 REVISED MRI CRITERIA
A CURRENT VIEW ON THE MRI DIAGNOSIS OF MULTIPLE SCLEROSIS: AN UPDATE OF 2016 REVISED MRI CRITERIA

To cite this article:

Briukhov VV, Krotenkova IA, Morozova SN, Krotenkova MV. A current view on the MRI diagnosis of multiple sclerosis: an update of 2016 revised MRI criteria. S.S. Korsakov Journal of Neurology and Psychiatry. 2017;117(2‑2):66‑73. (In Russ.)
https://doi.org/10.17116/jnevro20171172266-73

Подписка 2026 Журнал неврологии и психиатрии им. С.С. Корсакова. Спецвыпуски (S.S. Korsakov Journal of Neurology and Psychiatry (special issues))
МСФ на ЯМ
Использование инфографики авторами научных работ
Close metadata
Recommended articles:
Cognitive impairment in patients with multiple scle­rosis. S.S. Korsakov Journal of Neurology and Psychiatry. 2025;(4-2):67-73
Mole­cular mechanisms of acute disseminated ence­phalomyelitis. S.S. Korsakov Journal of Neurology and Psychiatry. 2025;(7-2):7-11
Features of the prevalence of dege­nerative-dystrophic changes in the cervical spine with a different nature of the course of the vertebral arte­ries. Russian Journal of Operative Surgery and Clinical Anatomy. 2024;(4-2):33-38
Hormonal contraception methods and multiple scle­rosis. S.S. Korsakov Journal of Neurology and Psychiatry. 2025;(1):24-30
Epidemiology of multiple scle­rosis in the city of Novo­sibirsk. S.S. Korsakov Journal of Neurology and Psychiatry. 2025;(1):119-127
Comparing the effi­cacy of divo­zilimab and second-line treatments for rela­psing-remitting multiple scle­rosis in the Russian Fede­ration: a systematic review and network meta-analysis. S.S. Korsakov Journal of Neurology and Psychiatry. 2025;(2):58-68
The influence of gender on the morphometric variability of the medu­lla oblo­ngata and pons in adults, taking into account the type of skull base acco­rding to MRI data. Russian Journal of Operative Surgery and Clinical Anatomy. 2025;(1):15-21
Three-dimensional mode­ling and intraoperative navi­gation in the diagnosis and treatment of various forms of adenomyosis. Russian Journal of Human Reproduction. 2025;(2):92-100
A clinical case of X-linked adre­noleukodystrophy. S.S. Korsakov Journal of Neurology and Psychiatry. 2025;(4):102-107
Arti­ficial inte­lligence capa­bilities in multiple scle­rosis. S.S. Korsakov Journal of Neurology and Psychiatry. 2025;(5):14-21
Abstract:

Magnetic resonance imaging (MRI) is the primary method for confirming the clinical diagnosis of multiple sclerosis (MS). The article presents the current data on using MRI of the brain and spinal cord for diagnosis in suspected MS. Special attention is paid to the MRI criteria of McDonald and MAGNIMS for relapsing-remitting MS (RRMS) and primary-progressive MS (PPMS) in the latest revisions of 2010 and 2016. The information provided can help radiologists and neurologists to optimize the use of MRI in clinical practice for diagnosis of MS.

Keywords:

magnetic resonance imaging
multiple sclerosis
MRI criteria
relapsing-remitting MS
primary progressive MS

Authors:

Briukhov V.V.

Krotenkova I.A.

FGBU "Nauchnyĭ tsentr nevrologii" RAN, Moskva

Morozova S.N.

Research Center of Neurology, Russian Academy of Sciences, Moscow

Krotenkova M.V.

Nauchnyĭ tsentr nevrologii RAMN, Moskva

Close metadata

References:

  1. McDonald WI et al. Recommended diagnostic criteria for multiple sclerosis: guidelines from the International Panel on the diagnosis of multiple sclerosis. Annals of Neurology. 2001;50:121-127. doi:10.1002/ana.1032
  2. Polman CH et al. Diagnostic criteria for multiple sclerosis: 2005 revisions to the «McDonald Criteria». Annals of Neurology. 2005;58:840-846. doi:10.1002/ana.20703
  3. Polman CH et al. Diagnostic criteria for multiple sclerosis: 2010 revisions to the McDonald criteria. Annals of Neurology. 2011;69:292-302. doi:10.1002/ana.22366
  4. Poser CM et al. New diagnostic criteria for multiple sclerosis: guidelines for research protocols. Annals of Neurology. 1983;13:227-231. doi:10.1002/ana.410130302
  5. Charil A et al. MRI and the diagnosis of multiple sclerosis: expanding the concept of «no better explanation». The Lancet Neurology. 2006;5:841-852. doi:10.1016/s1474-4422(06)70572-5
  6. Miller DH et al. Differential diagnosis of suspected multiple sclerosis: a consensus approach. Multiple Sclerosis Journal. 2008;14:1157-1174. doi:10.1177/1352458508096878
  7. Montalban X et al. MRI criteria for MS in patients with clinically isolated syndromes. Neurology. 2010;74:427-434. doi:10.1212/wnl.0b013e3181cec45c
  8. Filippi M, Rocca M, Ciccarelli O et al. MRI criteria for the diagnosis of multiple sclerosis: MAGNIMS consensus guidelines. The Lancet Neurology. 2016;15(3):292-303. doi:10.1016/s1474-4422(15)00393-2
  9. Montalban X et al. Primary progressive multiple sclerosis diagnostic criteria: a reappraisal. Multiple Sclerosis Journal. 2009;15:1459-1465. doi:10.1177/1352458509348422
  10. Dobson R, Ramagopalan S, Davis A, Giovannoni G. Cerebrospinal fluid oligoclonal bands in multiple sclerosis and clinically isolated syndromes: a meta-analysis of prevalence, prognosis and effect of latitude. Journal of Neurology, Neurosurgery & Psychiatry. 2013;84:909-914 doi: 10.1136/jnnp-2012-304695
  11. Kelly SB et al. A proposed modification to the McDonald 2010 criteria for the diagnosis of primary progressive multiple sclerosis. Multiple Sclerosis Journal. 2013;19:1095-1100. doi:10.1177/1352458512464829
  12. Rovira A at al. MAGNIMS consensus guidelines on the use of MRI in multiple sclerosis — clinical implementation in the diagnostic process. Nature Reviews Neurology. 2015;11:471-482. doi:10.1038/nrneurol.2015.106
  13. Sadaka Y et al. 2010 McDonald criteria for diagnosing pediatric multiple sclerosis. Annals of Neurology. 2012;72:211-223. doi:10.1002/ana.23575
  14. Kornek B et al. Evaluation of the 2010 McDonald multiple sclerosis criteria in children with a clinically isolated syndrome. Multiple Sclerosis Journal. 2012;18:1768-1774. doi:10.1177/1352458512444661
  15. Huh SY et al. The usefulness of brain MRI at onset in the differentiation of multiple sclerosis and seropositive neuromyelitis optica spectrum disorders. Multiple Sclerosis Journal. 2014;20:695-704. doi:10.1177/1352458513506953
  16. Absinta M, Rocca M, Colombo B et al. Patients with migraine do not have MRI-visible cortical lesions. Neurology. 2012;259:2695-2698. doi:10.1007/s00415-012-6571-x
  17. Ruet A, Arrambide G, Brochet B et al. Early predictors of multiple sclerosis after a typical clinically isolated syndrome. Multiple Sclerosis Journal. 2014;20:1721-1726. doi:10.1177/1352458514533397
  18. Ruet A, Deloire M, Ouallet J, Molinier S, Brochet B. Predictive factors for multiple sclerosis in patients with clinically isolated spinal cord syndrome. Multiple Sclerosis Journal. 2011;17:312-318. doi:10.1177/1352458510386999
  19. Moraal B, Pohl C, Uitdehaag B, et al. Magnetic resonance imaging predictors of conversion to multiple sclerosis in the BENEFIT study. Archives of Neurology. 2009;66:1345-1352. doi:10.1001/archneurol.2009.243
  20. Kim S, Richman D, Johnson W, Hald J, Agius M. Limited utility of current MRI criteria for distinguishing multiple sclerosis from common mimickers: primary and secondary CNS vasculitis, lupus and Sjogren’s syndrome. Multiple Sclerosis Journal. 2014;20:57-63. doi:10.1177/1352458513491329
  21. Kidd D, Barkhof F, McConnell R, Algra P, Allen I, Revesz T. Cortical lesions in multiple sclerosis. Brain. 1999;122:17-26. doi:10.1093/brain/122.1.17
  22. Geurts J, Pouwels P, Uitdehaag B, Polman C, Barkhof F, Castelijns J. Intracortical lesions in multiple sclerosis: improved detection with 3D double inversion-recovery MR imaging. Radiology. 2005;236:254-260. doi:10.1148/radiol.2361040450
  23. Seewann A, Kooi E, Roosendaal S. et al. Postmortem verification of MS cortical lesion detection with 3D DIR. Neurology. 2012;78:302-308. doi:10.1212/wnl.0b013e31824528a0
  24. Kelly S, Kinsella K, Duggan M, Tubridy N, McGuigan C, Hutchinson M. A proposed modification to the McDonald 2010 criteria for the diagnosis of primary progressive multiple sclerosis. Multiple Sclerosis Journal. 2012;19(8):1095-1100. doi:10.1177/1352458512464829
  25. Bryukhov VV, Popova EV, Krotenkova IA, Boyko AN. Radiologically isolated syndrome — MRI criteria and management tactics. Zhurnal nevrologii i psihiatrii im. S.S. Korsakova. 2016;116:10(2):52-57. (In Russ.).
  26. Huh SY et al. The usefulness of brain MRI at onset in the differentiation of multiple sclerosis and seropositive neuromyelitis optica spectrum disorders. Multiple Sclerosis Journal. 2014;20:695-704. doi:10.1177/1352458513506953
  27. Wattjes MP et al. Prognostic value of high-field proton magnetic resonance spectroscopy in patients presenting with clinically isolated syndromes suggestive of multiple sclerosis. Neuroradiology. 2008;50:123-129. doi:10.1007/s00234-007-0325-y
  28. Filippi M, Agosta F. Imaging biomarkers in multiple sclerosis. Journal of Magnetic Resonance Imaging. 2010;31:770-788. doi:10.1002/jmri.22102
  29. Rovaris M et al. A 3-year diffusion tensor MRI study of grey matter damage progression during the earliest clinical stage of MS. Journal of Neurology. 2008;255:1209-1214. doi:10.1007/s00415-008-0877-8
  30. Barcella V et al. Evidence for retrochiasmatic tissue loss in Leber’s hereditary optic neuropathy. Human Brain Mapping. 2010;31:1900-1906. doi:10.1002/hbm.20985
  31. Yu C et al. Pathogenesis of normal-appearing white matter damage in neuromyelitis optica: diffusion-tensor MR imaging. Radiology. 2008;246:222-228. doi:10.1148/radiol.2461062075
  32. Kang H et al. Application and a proposed modification of the McDonald criteria for the diagnosis of multiple sclerosis in a Canadian cohort of patients with clinically isolated syndromes. Multiple Sclerosis Journal. 2014;20:458-463. doi:10.1177/1352458513475492
  33. Mitjana R et al. Diagnostic value of brain chronic black holes on T1-weighted MR images in clinically isolated syndromes. Multiple Sclerosis Journal. 2014;20:1471-1477. doi:10.1177/1352458514526083
  34. Bryukhov VV, Kulikova SN, Krotenkova MV, Peresedova AV, Zavalishin IA. State-of-the-art neuroimaging techniques in pathogenesis of multiple sclerosis. Annaly klinicheskoj i jeksperimental'noj nevrologii. 2013;3:47-53. (In Russ.).
  35. Tallantyre EC et al. Ultra‑high‑field imaging distinguishes MS lesions from asymptomatic white matter lesions. Neurology. 2011;76:534-539. doi:10.1212/wnl.0b013e31820b7630
  36. Haacke EM, Xu Y, Cheng YC, Reichenbach JR. Susceptibility weighted imaging (SWI). Magnetic Resonance in Medicine. 2004;52:612-618. doi:10.1002/mrm.20198
  37. Kilsdonk ID et al. Improved differentiation between MS and vascular brain lesions using FLAIR* at 7 Tesla. European Radiology. 2014;24:841-849. doi:10.1007/s00330-013-3080-y
  38. Absinta M et al. Seven-tesla phase imaging of acute multiple sclerosis lesions: a new window into the inflammatory process. Annals of Neurology. 2013;74:669-678. doi:10.1002/ana.23959
  39. Kau T et al. The «central vein sign»: is there a place for susceptibility weighted imaging in possible multiple sclerosis? European Radiology. 2013;23:1956-1962. doi:10.1007/s00330-013-2791-4
  40. Sati P et al. Rapid, high-resolution, whole-brain, susceptibility-based MRI of multiple sclerosis. Multiple Sclerosis Journal. 2014;20:1464-1470. doi:10.1177/1352458514525868
  41. Hagemeier J et al. Phase white matter signal abnormalities in patients with clinically isolated syndrome and other neurologic disorders. American Journal of Neuroradiology. 2014;35:1916-1923. doi:10.3174/ajnr.a3969
  42. Simon B et al. Improved in vivo detection of cortical lesions in multiple sclerosis using double inversion recovery MR imaging at 3 Tesla. European Radiology. 2010;20:1675-1683. doi:10.1007/s00330-009-1705-y
  43. Filippi M et al. Intracortical lesions: relevance for new MRI diagnostic criteria for multiple sclerosis. Neurology. 2010;75:1988-1994. doi:10.1212/wnl.0b013e3181ff96f6
  44. Pestalozza IF et al. Monthly brain magnetic resonance imaging scans in patients with clinically isolated syndrome. Multiple Sclerosis Journal. 2005;11:390-394. doi:10.1191/1352458505ms1175oa
  45. Lebrun C et al. Association between clinical conversion to multiple sclerosis in radiologically isolated syndrome and magnetic resonance imaging, cerebrospinal fluid, and visual evoked potential: follow-up of 70 patients. Archives of Neurology. 2009;66:841-846. doi:10.1001/archneurol.2009.119
  46. Bryukhov VV, Krotenkova IA, Morozova SN, Krotenkova MV. Standardization of MRI studies in multiple sclerosis. Zhurnal nevrologii i psihiatrii im. S.S. Korsakova. 2016;116:10(2):27-34. (In Russ.).
Contact the author
Email
Message
The publishing house "Media Sphere" does not provide treatment services, does not give recommendations on contacting medical institutions and specific specialists, on the prescription of medicines and dietary supplements.

Email Confirmation

An email was sent to test@gmail.com with a confirmation link. Follow the link from the letter to complete the registration on the site.

Email Confirmation

Contact us
If you have any questions, complaints or suggestions, please use this feedback form.
Email
Message
The publishing house "Media Sphere" does not provide treatment services, does not give recommendations on contacting medical institutions and specific specialists, on the prescription of medicines and dietary supplements.
Submit Application

You can become an author of one of our magazines, send a request and we will consider it in during the day.

Name
Phone
E-mail
Message
Login
Registration
E-mail
Password
Forgot Password?

Log in to the site using your account in one of the services

Password recovery
E-mail
Login
Register

We use cооkies to improve the performance of the site. By staying on our site, you agree to the terms of use of cооkies. To view our Privacy and Cookie Policy, please. click here.