The site of the Media Sphera Publishers contains materials intended solely for healthcare professionals.
By closing this message, you confirm that you are a certified medical professional or a student of a medical educational institution.

Login
EN
+7 (495) 482-4118
+7 (495) 482-0604
+8 800 250-18-12
  • (toll-free number for subscriptions)
    Mon-Fri from 10 a.m. to 6 p.m.

  • © 1998-2025
+7 (495) 482-43-29
EN
All journals
Journal
Year
Year
Search result: 0

Krylov V.V.

FGBU MRNTs Minzdrava Rossii, Obninsk

Guekht A.B.

Moscow Research and Clinical Centre for Neuropsychiatry;
Pirogov Russian National Research Medical University

Trifonov I.S.

A.I. Evdokimov Moscow Medical University, Moscow, Russian Federation

Lebedeva A.V.

FGBU "Federal'nyĭ nauchnyĭ tsentr transplantologii i iskusstvennykh organov im. akad. V.I. Shumakova" Minzdrava Rossii, Moskva

Kaĭmovskiĭ I.L.

Gorodskaia klinicheskaia bol'nitsa # 12, Moskva

Sinkin M.V.

N.V. Sklifosovsky First Aid Scientific Research Institute, Moscow, Russia

Grigorieva Е.V.

Federal State Budgetary Institution «Federal Center of Traumatology, Orthopedics and endoprosthesis replacement» of Ministry of Health of the Russian Federation, Cheboksary, Russia

Grishkina M.N.

Moscow Research and Clinical Center for Neuropsychiatry, Moscow

Shishkina L.V.

Burdenko Neurosurgery Institute, Moscow, Russia

Kochetkova O.O.

Buyanov City Clinical Hospital, Moscow, Russia

Outcomes of surgical treatment of patients with pharmacoresistant epilepsy

Authors:

Krylov V.V., Guekht A.B., Trifonov I.S., Lebedeva A.V., Kaĭmovskiĭ I.L., Sinkin M.V., Grigorieva Е.V., Grishkina M.N., Shishkina L.V., Kochetkova O.O.

More about the authors

Journal: S.S. Korsakov Journal of Neurology and Psychiatry. 2016;116(9‑2): 13‑18

DOI: 10.17116/jnevro20161169213-18

Read: 4572 times

Download PDF (RU)
Contact the author
Table of contents

OUTCOMES OF SURGICAL TREATMENT OF PATIENTS WITH PHARMACORESISTANT EPILEPSY
OUTCOMES OF SURGICAL TREATMENT OF PATIENTS WITH PHARMACORESISTANT EPILEPSY

To cite this article:

Krylov VV, Guekht AB, Trifonov IS, et al. . Outcomes of surgical treatment of patients with pharmacoresistant epilepsy. S.S. Korsakov Journal of Neurology and Psychiatry. 2016;116(9‑2):13‑18. (In Russ.)
https://doi.org/10.17116/jnevro20161169213-18

Подписка 2026 Журнал неврологии и психиатрии им. С.С. Корсакова. Спецвыпуски (S.S. Korsakov Journal of Neurology and Psychiatry (special issues))
 
МСФ на ЯМ
Использование инфографики авторами научных работ
Close metadata
Recommended articles:
Personality profile caused by epilepsy acco­rding to the «Big Five» model. S.S. Korsakov Journal of Neurology and Psychiatry. 2024;(10):16-21
Brain microstructural abno­rmalities asse­ssed by diffusion kurtosis MRI in patients with focal temporal lobe epilepsy. S.S. Korsakov Journal of Neurology and Psychiatry. 2024;(11):171-177
Treatment of knee osteoarthritis with auto­logous stro­mal-vascular fraction of adipose tissue. Rege­nerative Biotechnologies, Preventive, Digi­tal and Predictive Medi­cine. 2024;(4):27-37
Conservative treatment for avascular necrosis of the femo­ral head: a systematic review. Rege­nerative Biotechnologies, Preventive, Digi­tal and Predictive Medi­cine. 2024;(4):52-67
Influence of non-opiate analgesia on postoperative pain inte­nsity and patient sati­sfaction. Piro­gov Russian Journal of Surgery. 2024;(12):74-80
Ototoxicity caused by anti-epileptic drugs. S.S. Korsakov Journal of Neurology and Psychiatry. 2024;(12):14-19
Abse­nce status epilepticus in adults. S.S. Korsakov Journal of Neurology and Psychiatry. 2024;(12):47-56
Como­rbid anxiety diso­rders in patients with neurological pathology: current state of the problem and the role of etifoxine in treatment stra­tegy. S.S. Korsakov Journal of Neurology and Psychiatry. 2024;(12):126-136
Influence of cardiovascular complications on 30-day mortality after major abdo­minal surgery: a regional multiple-center study. Russian Journal of Anesthesiology and Reanimatology. 2025;(1):69-75
Bacterial cellulose-based mate­rials in medi­cine. Medi­cal Technologies. Asse­ssment and Choice. 2025;(1):84-91
Abstract:

Objective. To evaluate the results of surgical treatment of patients with pharmacoresistant epilepsy. Material and methods. Examination and surgical treatment of 61 patients with pharmacoresistant forms of symptomatic epilepsy were performed from 01.01.14 to 01.05.16. Results and conclusion. The results confirmed the safety and efficacy of the surgical treatment of pharmacoresistant epilepsy. After 12 months, seizures were controlled in 69% of operated patients. The necessity of complex examination of all patients with pharmacoresistant epilepsy to make a decision about possible surgery is shown.

Keywords:

epilepsy
surgery
focal cortical dysplasia
hippocampal sclerosis
surgical treatment of epilepsy
pharmacoressistance

Authors:

Krylov V.V.

FGBU MRNTs Minzdrava Rossii, Obninsk

Guekht A.B.

Moscow Research and Clinical Centre for Neuropsychiatry;
Pirogov Russian National Research Medical University

Trifonov I.S.

A.I. Evdokimov Moscow Medical University, Moscow, Russian Federation

Lebedeva A.V.

FGBU "Federal'nyĭ nauchnyĭ tsentr transplantologii i iskusstvennykh organov im. akad. V.I. Shumakova" Minzdrava Rossii, Moskva

Kaĭmovskiĭ I.L.

Gorodskaia klinicheskaia bol'nitsa # 12, Moskva

Sinkin M.V.

N.V. Sklifosovsky First Aid Scientific Research Institute, Moscow, Russia

Grigorieva Е.V.

Federal State Budgetary Institution «Federal Center of Traumatology, Orthopedics and endoprosthesis replacement» of Ministry of Health of the Russian Federation, Cheboksary, Russia

Grishkina M.N.

Moscow Research and Clinical Center for Neuropsychiatry, Moscow

Shishkina L.V.

Burdenko Neurosurgery Institute, Moscow, Russia

Kochetkova O.O.

Buyanov City Clinical Hospital, Moscow, Russia

Close metadata

References:

  1. Karlov VA. Treatment of epilepsy. Epilepsy in children and adult women and men. Ed. Karlov V.A. M.: Medicina; 2010. (In Russ.).
  2. Annegers J, Hauser W, Elveback L. Remission of Seizures and Relapse in Patients with Epilepsy. Epilepsia. 1979;20(6):729-737. doi: 10.1111/j.1528-1157.1979.tb04857.x
  3. Shafer S, Hauser W, Annegers J, Klass D. EEG and Other Early Predictors of Epilepsy Remission: A Community Study. Epilepsia. 1988;29(5):590-600. doi: 10.1111/j.1528-1157.1988.tb03767.x
  4. Banerjee P, Filippi D, Allen Hauser W. The descriptive epidemiology of epilepsy — A review. Epilepsy Research. 2009;85(1):31-45. doi: 10.1016/j.eplepsyres.2009.03.003
  5. Wiebe S, Blume W, Girvin J, Eliasziw M. A Randomized, Controlled Trial of Surgery for Temporal-Lobe Epilepsy. New England Journal of Medicine. 2001;345(5):311-318. doi: 10.1056/nejm200108023450501.
  6. Lebedeva AV, Melikyan EG, Stepanenko AY, Chomutov VE, Guekht AB. The dynamics of the quality of life in patients with drug-resistant epilepsy for surgical treatments. Vestnik Natsional'nogo mediko-khirurgicheskogo tsentra im. N.I. Pirogova. 2011;3:67-70. (In Russ.).
  7. Baker G, Jacoby A, Buck D, Stalgis C, Monnet D. Quality of Life of People with Epilepsy: A European Study. Epilepsia. 1997;38(3):353-362. doi: 10.1111/j.1528-1157.1997.tb01128.x
  8. Wiebe S, Jette N. Pharmacoresistance and the role of surgery in difficult to treat epilepsy. Nature Reviews Neurology. 2012;8(12):669-677. doi:10.1038/nrneurol.2012.181.
  9. Téllez-Zenteno J, Ronquillo L, Moien-Afshari F, Wiebe S. Surgical outcomes in lesional and non-lesional epilepsy: A systematic review and meta-analysis. Epilepsy Research. 2010;89(2-3):310-318. doi: 10.1016/j.eplepsyres.2010.02.007
  10. Blümcke I, Thom M, Aronica E et al. The clinicopathologic spectrum of focal cortical dysplasias: A consensus classification proposed by an ad hoc Task Force of the ILAE Diagnostic Methods Commission1. Epilepsia. 2010;52(1):158-174. doi: 10.1111/j.1528-1167.2010.02777.x
  11. Engel Jr JVNP. Outcome with respect to epileptic seizures. Surgical treatment of the epilepsies.1993;609-621.
  12. Karlov VA. Key issues of epilepsy problems. Zhurnal nevrologii i psikhiatrii im. S.S. Korsakova. 2003;103(3):4.
  13. Kwan P, Arzimanoglou A, Berg A et al. Definition of drug resistant epilepsy: Consensus proposal by the ad hoc Task Force of the ILAE Commission on Therapeutic Strategies. Epilepsia. 2009;51(6):1069-1077. doi:10.1111/j.1528-1167.2009.02397.x
  14. Berg AT. Understanding the delay before epilepsy surgery: who develops intractable focal epilepsy and when? CNS spectrums. 2004;9(02):136-144.
  15. Benbadis S, Heriaud L, Tatum W, Vale F. Epilepsy surgery, delays and referral patterns—are all your epilepsy patients controlled? Seizure. 2003;12(3):167-170. doi: 10.1016/s1059-1311(02)00320-5
  16. Lowe N, Eldridge P, Varma T, Wieshmann U. The duration of temporal lobe epilepsy and seizure outcome after epilepsy surgery. Seizure. 2010;19(5):261-263. doi: 10.1016/j.seizure.2010.02.011
  17. Janszky J. Temporal lobe epilepsy with hippocampal sclerosis: predictors for long-term surgical outcome. Brain. 2004;128(2):395-404. doi: 10.1093/brain/awh358
  18. Engel J. Early Surgical Therapy for Drug-Resistant Temporal Lobe Epilepsy. JAMA. 2012;307(9):922. doi: 10.1001/jama.2012.220
  19. Hader W, Tellez-Zenteno J, Metcalfe A et al. Complications of epilepsy surgery — A systematic review of focal surgical resections and invasive EEG monitoring. Epilepsia. 2013;54(5):840-847. doi: 10.1111/epi.12161
  20. de Flon P, Kumlien E, Reuterwall C, Mattsson P. Empirical evidence of underutilization of referrals for epilepsy surgery evaluation. European Journal of Neurology. 2010;17(4):619-625. doi: 10.1111/j.1468-1331.2009.02891.x
  21. Beisse F, Lagrèze W, Schmitz J, Schulze-Bonhage A. Gesichtsfelddefekte nach epilepsiechirurgischen Eingriffen. Ophthalmologe. 2014;111(10):942-947. doi: 10.1007/s00347-013-3013-9
  22. Winston G, Daga P, White M et al. Preventing visual field deficits from neurosurgery. Neurology. 2014;83(7):604-611. doi: 10.1212/wnl.0000000000000685
  23. Nilsson L, Ahlbom A, Farahmand B, Tomson T. Mortality in a Population-based Cohort of Epilepsy Surgery Patients. Epilepsia. 2003;44(4):575-581. doi: 10.1046/j.1528-1157.2003.03302.x
  24. Guekht A, Hauser W, Milchakova L, Churillin Y, Shpak A, Gusev E. The epidemiology of epilepsy in the Russian Federation. Epilepsy Research. 2010;92(2-3):209-218. doi: 10.1016/j.eplepsyres.2010.09.011
  25. Shorvon S, Tomson T. Sudden unexpected death in epilepsy. The Lancet. 2011;378(9808):2028-2038. doi: 10.1016/s0140-6736(11)60176-1
  26. Ryvlin P, Kahane P. Does epilepsy surgery lower the mortality of drug-resistant epilepsy? Epilepsy Research. 2003;56(2-3):105-120. doi: 10.1016/j.eplepsyres.2003.10.001
  27. Lawn N, Bamlet W, Radhakrishnan K, O'Brien P, So E. Injuries due to seizures in persons with epilepsy: A population-based study. Neurology. 2004;63(9):1565-1570. doi: 10.1212/01.wnl.0000142991.14507.b5
  28. Téllez-Zenteno J, Hunter G, Wiebe S. Injuries in people with self-reported epilepsy: A population-based study. Epilepsia. 2008;49(6):954-961. doi: 10.1111/j.1528-1167.2007.01499.x
  29. Beghi E, Cornaggia C. Morbidity and Accidents in Patients with Epilepsy: Results of a European Cohort Study. Epilepsia. 2002;43(9):1076-1083. doi: 10.1046/j.1528-1157.2002.18701.x
  30. Lu B, Elliott J. Beyond seizures and medications: Normal activity limitations, social support, and mental health in epilepsy. Epilepsia. 2011;53(2):25-28. doi: 10.1111/j.1528-1167.2011.03331.x
  31. Selassie A, Wilson D, Martz G, Smith G, Wagner J, Wannamaker B. Epilepsy beyond seizure: A population-based study of comorbidities. Epilepsy Research. 2014;108(2):305-315. doi: 10.1016/j.eplepsyres.2013.12.002
  32. Dalmagro C, Velasco T, Bianchin M et al. Psychiatric comorbidity in refractory focal epilepsy: A study of 490 patients. Epilepsy & Behavior. 2012;25(4):593-597. doi: 10.1016/j.yebeh.2012.09.026
  33. Hesdorffer D, Ishihara L, Mynepalli L, Webb D, Weil J, Hauser W. Epilepsy, suicidality, and psychiatric disorders: A bidirectional association. Annals of Neurology. 2012;72(2):184-191. doi: 10.1002/ana.23601
  34. Sperling MR. The consequences of uncontrolled epilepsy. CNS Spectrums. 2004;9(2):98-101.
Contact the author
Email
Message
The publishing house "Media Sphere" does not provide treatment services, does not give recommendations on contacting medical institutions and specific specialists, on the prescription of medicines and dietary supplements.

Email Confirmation

An email was sent to test@gmail.com with a confirmation link. Follow the link from the letter to complete the registration on the site.

Email Confirmation

Contact us
If you have any questions, complaints or suggestions, please use this feedback form.
Email
Message
The publishing house "Media Sphere" does not provide treatment services, does not give recommendations on contacting medical institutions and specific specialists, on the prescription of medicines and dietary supplements.
Submit Application

You can become an author of one of our magazines, send a request and we will consider it in during the day.

Name
Phone
E-mail
Message
Login
Registration
E-mail
Password
Forgot Password?

Log in to the site using your account in one of the services

Password recovery
E-mail
Login
Register

We use cооkies to improve the performance of the site. By staying on our site, you agree to the terms of use of cооkies. To view our Privacy and Cookie Policy, please. click here.