Oral disease modifying therapy of multiple sclerosis: the current view

Kappos L.

Nevrologicheskoe otdelenie i tsentr rasseiannogo skleroza, Kantongospital' Bazelia, Shveĭtsariia

Boĭko A.N.

KGBUZ "Krasnoiarskiĭ kraevoĭ Tsentr po profilaktike i bor'be so SPID i infektsionnymi zabolevaniiami"

Scopus AuthorID: 57224826008
ORCID: 0000-0001-6476-6417

Oral disease modifying therapy of multiple sclerosis: the current view

Authors:

Kappos L., Boĭko A.N.

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Journal: S.S. Korsakov Journal of Neurology and Psychiatry. 2014;114(2‑2): 63‑71

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To cite this article:

Kappos L, Boĭko AN. Oral disease modifying therapy of multiple sclerosis: the current view. S.S. Korsakov Journal of Neurology and Psychiatry. 2014;114(2‑2):63‑71.

Подписка 2025-2 (S.S. Korsakov Journal of Neurology and Psychiatry (special issues))

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The review includes data on experimental and clinical studies of new oral methods of multiple sclerosis (MS) disease modifying therapy (DMT). The mechanisms of action, results of clinical trials of stages II and III with the data on their clinical and MRI-efficacy, tolerability and safety of fingolimod, dimethylfumarate (BG-12), teriflunomide and laquinimod are included. The risk management plans for possible side-effects of every product and the peculiarities of their use in individually selected MS treatment are discussed.

Keywords:

multiple sclerosis

DMT

oral therapy