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Zakharov A.V.

Kafedra nevrologii i neĭrokhirurgii Samarskogo gosudarstvennogo meditsinskogo universiteta;
Samarskaia oblastnaia klinicheskaia bol'nitsa im. Kalinina

Khivintseva E.V.

Kafedra nevrologii i neĭrokhirurgii Samarskogo gosudarstvennogo meditsinskogo universiteta;
Samarskaia oblastnaia klinicheskaia bol'nitsa im. Kalinina

Poverennova I.E.

Kafedra nevrologii i neĭrokhirurgii Samarskogo gosudarstvennogo meditsinskogo universiteta

Gindullina E.A.

Kafedra nevrologii i neĭrokhirurgii Samarskogo gosudarstvennogo meditsinskogo universiteta;
Samarskaia oblastnaia klinicheskaia bol'nitsa im. Kalinina

Vlasov Ia.V.

Kafedra nevrologii i neĭrokhirurgii Samarskogo gosudarstvennogo meditsinskogo universiteta

Sineok E.V.

Kafedra nevrologii i neĭrokhirurgii Samarskogo gosudarstvennogo meditsinskogo universiteta

Assessment of the risk of the transition of a monofocal clinically isolated syndrome to clinically definite multiple sclerosis

Authors:

Zakharov A.V., Khivintseva E.V., Poverennova I.E., Gindullina E.A., Vlasov Ia.V., Sineok E.V.

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Journal: S.S. Korsakov Journal of Neurology and Psychiatry. 2013;113(2‑2): 28‑31

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To cite this article:

Zakharov AV, Khivintseva EV, Poverennova IE, Gindullina EA, Vlasov IaV, Sineok EV. Assessment of the risk of the transition of a monofocal clinically isolated syndrome to clinically definite multiple sclerosis. S.S. Korsakov Journal of Neurology and Psychiatry. 2013;113(2‑2):28‑31. (In Russ.)

Подписка 2026 Журнал неврологии и психиатрии им. С.С. Корсакова. Спецвыпуски (S.S. Korsakov Journal of Neurology and Psychiatry (special issues))
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Abstract:

We followed up 102 patients with a monofocal clinically isolated syndrome (CIS) during 8 years. Factors determining its transition to definite multiple sclerosis were singled out according to the data of anamnesis and MRI scans. Age of patients at the onset of CIS and the volume of demyelination measured by the first MRI were the most significant predictors of the transition of CIS to definite multiple sclerosis. A mathematical model based on logistic regression analysis for the estimation of the risk of this transition is suggested.

Keywords:

multiple sclerosis
monofocal isolated syndrom
clinical transition
neurovisualization

Authors:

Zakharov A.V.

Kafedra nevrologii i neĭrokhirurgii Samarskogo gosudarstvennogo meditsinskogo universiteta;
Samarskaia oblastnaia klinicheskaia bol'nitsa im. Kalinina

Khivintseva E.V.

Kafedra nevrologii i neĭrokhirurgii Samarskogo gosudarstvennogo meditsinskogo universiteta;
Samarskaia oblastnaia klinicheskaia bol'nitsa im. Kalinina

Poverennova I.E.

Kafedra nevrologii i neĭrokhirurgii Samarskogo gosudarstvennogo meditsinskogo universiteta

Gindullina E.A.

Kafedra nevrologii i neĭrokhirurgii Samarskogo gosudarstvennogo meditsinskogo universiteta;
Samarskaia oblastnaia klinicheskaia bol'nitsa im. Kalinina

Vlasov Ia.V.

Kafedra nevrologii i neĭrokhirurgii Samarskogo gosudarstvennogo meditsinskogo universiteta

Sineok E.V.

Kafedra nevrologii i neĭrokhirurgii Samarskogo gosudarstvennogo meditsinskogo universiteta

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