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Sokolova E.A.

Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of the Russian Academy of Sciences, Novosibirsk, Russia;
Novosibirsk State University, Novosibirsk, Russia

Malkova N.A.

Novosibirskiĭ okruzhnoĭ tsentr rasseiannogo skleroza

Korobko D.S.

Oblastnoĭ tsentr rasseiannogo skleroza, Gosudarstvennaia novosibirskaia oblastnaia klinicheskaia bol'nitsa

Rozhdestvenskiĭ A.S.

Kafedra nevrologii i neĭrokhirurgii s kursom meditsinskoĭ genetiki Omskoĭ gosudarstvennoĭ meditsinskoĭ akademii

Kakulia A.V.

Kafedra nevrologii i neĭrokhirurgii s kursom meditsinskoĭ genetiki Omskoĭ gosudarstvennoĭ meditsinskoĭ akademii

Khanokh E.V.

Kafedra nevrologii i neĭrokhirurgii s kursom meditsinskoĭ genetiki Omskoĭ gosudarstvennoĭ meditsinskoĭ akademii

Delov R.A.

Kafedra nevrologii i neĭrokhirurgii s kursom meditsinskoĭ genetiki Omskoĭ gosudarstvennoĭ meditsinskoĭ akademii

Platonov F.A.

Respublikanskaia bol'nitsa #2, Iakutsk;
Meditsinskiĭ institut Severo-Vostochnogo federal'nogo universiteta im. M.K. Ammosova, Iakutsk

Popova T.E.

Meditsinskiĭ institut Severo-Vostochnogo federal'nogo universiteta im. M.K. Ammosova, Iakutsk

Aref'eva E.G.

Kemerovskaia oblastnaia klinicheskaia bol'nitsa

Zagorskaia N.N.

Kemerovskaia oblastnaia klinicheskaia bol'nitsa

Alifirova V.M.

Sibirskiĭ gosudarstvennyĭ meditsinskiĭ universitet, Tomsk, Russia

Titova M.A.

Sibirskiĭ gosudarstvennyĭ meditsinskiĭ universitet, Tomsk

Smagina I.V.

Otdelenie nevrologii kraevoĭ klinicheskoĭ bolnitsy, Barnaul;
kafedra nervnykh bolezneĭ s kursom nevrologii i refleksoterapii fakulteta povysheniia kvalifikatsii i PPS, Barnaul;
kafedra biokhimii i klinicheskoĭ laboratornoĭ diagnostiki Altaĭskogo gosudarstvennogo meditsinskogo universiteta, Barnaul;
Novosibirskiĭ gosudarstvennyĭ universitet, Novosibirsk

Elchaninova S.A.

Popovtseva A.V.

Altaĭskiĭ gosudarstvennyĭ meditsinskiĭ universitet, Barnaul

Lichenko Iu.N.

Kraevaia klinicheskaia bol'nitsa, Barnaul

Dymova M.A.

Institut khimicheskoĭ biologii i fundamental'noĭ meditsiny Sibirskogo otdeleniia RAN, Novosibirsk

Vaĭner A.S.

Institut khimicheskoĭ biologii i fundamental'noĭ meditsiny Sibirskogo otdeleniia RAN, Novosibirsk;
Novosibirskiĭ gosudarstvennyĭ universitet

P'iankova O.V.

Institut khimicheskoĭ biologii i fundamental'noĭ meditsiny Sibirskogo otdeleniia RAN, Novosibirsk;
Novosibirskiĭ gosudarstvennyĭ universitet

Oskorbin I.P.

Institut khimicheskoĭ biologii i fundamental'noĭ meditsiny Sibirskogo otdeleniia RAN, Novosibirsk;
Novosibirskiĭ gosudarstvennyĭ universitet

Kechin A.A.

Institut khimicheskoĭ biologii i fundamental'noĭ meditsiny Sibirskogo otdeleniia RAN, Novosibirsk;
Novosibirskiĭ gosudarstvennyĭ universitet

Puzyrev V.P.

Nauchno-issledovatel'skiĭ institut meditsinskoĭ genetiki Sibirskogo otdeleniia RAMN, Tomsk

Kulakova O.G.

Kafedra nevrologii i neĭrokhirurgii i kafedra molekuliarnoĭ biologii i biotekhnologii Rossiĭskogo natsional'nogo issledovatel'skogo meditsinskogo universiteta im. N.I. Pirogova, Moskva

Tsareva E.Iu.

Kafedra nevrologii i neĭrokhirurgii i kafedra molekuliarnoĭ biologii i biotekhnologii Rossiĭskogo natsional'nogo issledovatel'skogo meditsinskogo universiteta im. N.I. Pirogova, Moskva

Favorova O.O.

Kafedra nevrologii i neĭrokhirurgii i kafedra molekuliarnoĭ biologii i biotekhnologii Rossiĭskogo natsional'nogo issledovatel'skogo meditsinskogo universiteta im. N.I. Pirogova, Moskva

Shchur S.G.

Kafedra nevrologii i neĭrokhirurgii Rossiĭskogo natsional'nogo issledovatel'skogo meditsinskogo universiteta

Lashch N.Iu.

Kafedra nevrologii i neĭrokhirurgii Rossiĭskogo natsional'nogo issledovatel'skogo meditsinskogo universiteta

Popova N.F.

kafedra nevrologii i neĭrokhirurgii Rossiĭskogo gosudarstvennogo meditsinskogo universiteta;
gorodskaia klinicheskaia bol'nitsa #11

Popova E.V.

Kafedra nervnykh bolezneĭ fakul'teta poslevuzovskogo professional'nogo obrazovaniia vracheĭ Moskovskoĭ meditsinskoĭ akademii im. I.M. Sechenova

Gusev E.I.

Kafedra nevrologii i neĭrokhirurgii Rossiĭskogo gosudarstvennogo meditsinskogo universiteta, Moskva

Boĭko A.N.

KGBUZ "Krasnoiarskiĭ kraevoĭ Tsentr po profilaktike i bor'be so SPID i infektsionnymi zabolevaniiami"

Aul'chenko Iu.S.

Institut khimicheskoĭ biologii i fundamental'noĭ meditsiny Sibirskogo otdeleniia RAN, Novosibirsk;
Institut tsitologii i genetiki Sibirskogo otdeleniia RAN, Novosibirsk

Filipenko M.L.

Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of the Russian Academy of Sciences, Novosibirsk, Russia;
Novosibirsk State University, Novosibirsk, Russia

The first results of a combined all-Russian study on clinical genetics of multiple sclerosis

Authors:

Sokolova E.A., Malkova N.A., Korobko D.S., Rozhdestvenskiĭ A.S., Kakulia A.V., Khanokh E.V., Delov R.A., Platonov F.A., Popova T.E., Aref'eva E.G., Zagorskaia N.N., Alifirova V.M., Titova M.A., Smagina I.V., Elchaninova S.A., Popovtseva A.V., Lichenko Iu.N., Dymova M.A., Vaĭner A.S., P'iankova O.V., Oskorbin I.P., Kechin A.A., Puzyrev V.P., Kulakova O.G., Tsareva E.Iu., Favorova O.O., Shchur S.G., Lashch N.Iu., Popova N.F., Popova E.V., Gusev E.I., Boĭko A.N., Aul'chenko Iu.S., Filipenko M.L.

More about the authors

Journal: S.S. Korsakov Journal of Neurology and Psychiatry. 2013;113(2‑2): 6‑9

Read: 933 times

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To cite this article:

Sokolova EA, Malkova NA, Korobko DS, et al. . The first results of a combined all-Russian study on clinical genetics of multiple sclerosis. S.S. Korsakov Journal of Neurology and Psychiatry. 2013;113(2‑2):6‑9. (In Russ.)

Подписка 2026 Журнал неврологии и психиатрии им. С.С. Корсакова. Спецвыпуски (S.S. Korsakov Journal of Neurology and Psychiatry (special issues))
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Abstract:

Multiple sclerosis is a classic multifactorial disease in which etiology interaction of external factors and structural features of a large number of genes plays an important role. Identifying risk factors for multiple sclerosis and creating an integrated model of pathogenesis are urgent tasks of neurology. Revealing true risk factors is possible only in studies with sufficient statistical power, so with a large amount of samples. We conducted the association study of CD40 gene's polymorphisms and multiple sclerosis among residents of the Russian Federation. The results demonstrated the need to combine data from different researchers in clinical studies to increase the power of the study.

Keywords:

multiple sclerosis
power of study
assoceation
factor risk
CD40

Authors:

Sokolova E.A.

Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of the Russian Academy of Sciences, Novosibirsk, Russia;
Novosibirsk State University, Novosibirsk, Russia

Malkova N.A.

Novosibirskiĭ okruzhnoĭ tsentr rasseiannogo skleroza

Korobko D.S.

Oblastnoĭ tsentr rasseiannogo skleroza, Gosudarstvennaia novosibirskaia oblastnaia klinicheskaia bol'nitsa

Rozhdestvenskiĭ A.S.

Kafedra nevrologii i neĭrokhirurgii s kursom meditsinskoĭ genetiki Omskoĭ gosudarstvennoĭ meditsinskoĭ akademii

Kakulia A.V.

Kafedra nevrologii i neĭrokhirurgii s kursom meditsinskoĭ genetiki Omskoĭ gosudarstvennoĭ meditsinskoĭ akademii

Khanokh E.V.

Kafedra nevrologii i neĭrokhirurgii s kursom meditsinskoĭ genetiki Omskoĭ gosudarstvennoĭ meditsinskoĭ akademii

Delov R.A.

Kafedra nevrologii i neĭrokhirurgii s kursom meditsinskoĭ genetiki Omskoĭ gosudarstvennoĭ meditsinskoĭ akademii

Platonov F.A.

Respublikanskaia bol'nitsa #2, Iakutsk;
Meditsinskiĭ institut Severo-Vostochnogo federal'nogo universiteta im. M.K. Ammosova, Iakutsk

Popova T.E.

Meditsinskiĭ institut Severo-Vostochnogo federal'nogo universiteta im. M.K. Ammosova, Iakutsk

Aref'eva E.G.

Kemerovskaia oblastnaia klinicheskaia bol'nitsa

Zagorskaia N.N.

Kemerovskaia oblastnaia klinicheskaia bol'nitsa

Alifirova V.M.

Sibirskiĭ gosudarstvennyĭ meditsinskiĭ universitet, Tomsk, Russia

Titova M.A.

Sibirskiĭ gosudarstvennyĭ meditsinskiĭ universitet, Tomsk

Smagina I.V.

Otdelenie nevrologii kraevoĭ klinicheskoĭ bolnitsy, Barnaul;
kafedra nervnykh bolezneĭ s kursom nevrologii i refleksoterapii fakulteta povysheniia kvalifikatsii i PPS, Barnaul;
kafedra biokhimii i klinicheskoĭ laboratornoĭ diagnostiki Altaĭskogo gosudarstvennogo meditsinskogo universiteta, Barnaul;
Novosibirskiĭ gosudarstvennyĭ universitet, Novosibirsk

Elchaninova S.A.

Popovtseva A.V.

Altaĭskiĭ gosudarstvennyĭ meditsinskiĭ universitet, Barnaul

Lichenko Iu.N.

Kraevaia klinicheskaia bol'nitsa, Barnaul

Dymova M.A.

Institut khimicheskoĭ biologii i fundamental'noĭ meditsiny Sibirskogo otdeleniia RAN, Novosibirsk

Vaĭner A.S.

Institut khimicheskoĭ biologii i fundamental'noĭ meditsiny Sibirskogo otdeleniia RAN, Novosibirsk;
Novosibirskiĭ gosudarstvennyĭ universitet

P'iankova O.V.

Institut khimicheskoĭ biologii i fundamental'noĭ meditsiny Sibirskogo otdeleniia RAN, Novosibirsk;
Novosibirskiĭ gosudarstvennyĭ universitet

Oskorbin I.P.

Institut khimicheskoĭ biologii i fundamental'noĭ meditsiny Sibirskogo otdeleniia RAN, Novosibirsk;
Novosibirskiĭ gosudarstvennyĭ universitet

Kechin A.A.

Institut khimicheskoĭ biologii i fundamental'noĭ meditsiny Sibirskogo otdeleniia RAN, Novosibirsk;
Novosibirskiĭ gosudarstvennyĭ universitet

Puzyrev V.P.

Nauchno-issledovatel'skiĭ institut meditsinskoĭ genetiki Sibirskogo otdeleniia RAMN, Tomsk

Kulakova O.G.

Kafedra nevrologii i neĭrokhirurgii i kafedra molekuliarnoĭ biologii i biotekhnologii Rossiĭskogo natsional'nogo issledovatel'skogo meditsinskogo universiteta im. N.I. Pirogova, Moskva

Tsareva E.Iu.

Kafedra nevrologii i neĭrokhirurgii i kafedra molekuliarnoĭ biologii i biotekhnologii Rossiĭskogo natsional'nogo issledovatel'skogo meditsinskogo universiteta im. N.I. Pirogova, Moskva

Favorova O.O.

Kafedra nevrologii i neĭrokhirurgii i kafedra molekuliarnoĭ biologii i biotekhnologii Rossiĭskogo natsional'nogo issledovatel'skogo meditsinskogo universiteta im. N.I. Pirogova, Moskva

Shchur S.G.

Kafedra nevrologii i neĭrokhirurgii Rossiĭskogo natsional'nogo issledovatel'skogo meditsinskogo universiteta

Lashch N.Iu.

Kafedra nevrologii i neĭrokhirurgii Rossiĭskogo natsional'nogo issledovatel'skogo meditsinskogo universiteta

Popova N.F.

kafedra nevrologii i neĭrokhirurgii Rossiĭskogo gosudarstvennogo meditsinskogo universiteta;
gorodskaia klinicheskaia bol'nitsa #11

Popova E.V.

Kafedra nervnykh bolezneĭ fakul'teta poslevuzovskogo professional'nogo obrazovaniia vracheĭ Moskovskoĭ meditsinskoĭ akademii im. I.M. Sechenova

Gusev E.I.

Kafedra nevrologii i neĭrokhirurgii Rossiĭskogo gosudarstvennogo meditsinskogo universiteta, Moskva

Boĭko A.N.

KGBUZ "Krasnoiarskiĭ kraevoĭ Tsentr po profilaktike i bor'be so SPID i infektsionnymi zabolevaniiami"

Aul'chenko Iu.S.

Institut khimicheskoĭ biologii i fundamental'noĭ meditsiny Sibirskogo otdeleniia RAN, Novosibirsk;
Institut tsitologii i genetiki Sibirskogo otdeleniia RAN, Novosibirsk

Filipenko M.L.

Institute of Chemical Biology and Fundamental Medicine, Siberian Branch of the Russian Academy of Sciences, Novosibirsk, Russia;
Novosibirsk State University, Novosibirsk, Russia

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