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Shkil'niuk G.G.

Institut mozga cheloveka RAN, Sankt-Peterburg

Il'ves A.G.

Kataeva G.V.

Institut mozga cheloveka im. N.P. Bekhterevoĭ RAN, Sankt-Peterburg

Prakhova L.N.

Reznikova T.N.

Institut mozga cheloveka im. N.P. Bekhterevoĭ RAN, Sankt-Peterburg

Seliverstova N.A.

Institut mozga cheloveka im. N.P. Bekhterevoĭ RAN, Sankt-Peterburg

Stoliarov I.D.

The role of brain glucose metabolism in the development of cognitive dysfunctions in patients with remitting and secondary-progressive multiple sclerosis

Authors:

Shkil'niuk G.G., Il'ves A.G., Kataeva G.V., Prakhova L.N., Reznikova T.N., Seliverstova N.A., Stoliarov I.D.

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Journal: S.S. Korsakov Journal of Neurology and Psychiatry. 2012;112(2‑2): 41‑46

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To cite this article:

Shkil'niuk GG, Il'ves AG, Kataeva GV, Prakhova LN, Reznikova TN, Seliverstova NA, Stoliarov ID. The role of brain glucose metabolism in the development of cognitive dysfunctions in patients with remitting and secondary-progressive multiple sclerosis. S.S. Korsakov Journal of Neurology and Psychiatry. 2012;112(2‑2):41‑46. (In Russ.)

 
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To study mechanisms of development of cognitive dysfunctions in multiple sclerosis (MS), brain glucose metabolism has been investigated using PET method. We have studied 61 patients with different types of MS course. Correlations between cognitive dysfunctions and regional glucose metabolic rate were revealed. The authors suggest that metabolic dysfunctions of the grey matter play the important role in the pathogenesis of cognitive disturbances in MS.

Keywords:

multiple sclerosis
cognitive impairment
PET

Authors:

Shkil'niuk G.G.

Institut mozga cheloveka RAN, Sankt-Peterburg

Il'ves A.G.

Kataeva G.V.

Institut mozga cheloveka im. N.P. Bekhterevoĭ RAN, Sankt-Peterburg

Prakhova L.N.

Reznikova T.N.

Institut mozga cheloveka im. N.P. Bekhterevoĭ RAN, Sankt-Peterburg

Seliverstova N.A.

Institut mozga cheloveka im. N.P. Bekhterevoĭ RAN, Sankt-Peterburg

Stoliarov I.D.

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