Terahertz modulated infrared radiation in the complex treatment of patients in the acute period of ischemic stroke

Kiriyanova V.V.; Molodovskaya N.V.; Potapchuk A.A.; Zharova E.N.

doi:https://doi.org/10.17116/kurort2021980315

Kiriyanova V.V.

St. Petersburg State Pediatric Medical University

ORCID: 0000-0003-2412-7041

Molodovskaya N.V.

Semashko City Hospital No. 38

Potapchuk A.A.

Academician I.P. Pavlov First Saint Petersburg State Medical University

Zharova E.N.

I.I. Mechnikov Northwestern State Medical University

Terahertz modulated infrared radiation in the complex treatment of patients in the acute period of ischemic stroke

Authors:

Kiriyanova V.V., Molodovskaya N.V., Potapchuk A.A., Zharova E.N.

More about the authors

Journal: Problems of Balneology, Physiotherapy and Exercise Therapy. 2021;98(3): 5‑10

DOI: 10.17116/kurort2021980315

Read: 1916 times

Download PDF (RU)

Contact the author

Table of contents

To cite this article:

Kiriyanova VV, Molodovskaya NV, Potapchuk AA, Zharova EN. Terahertz modulated infrared radiation in the complex treatment of patients in the acute period of ischemic stroke. Problems of Balneology, Physiotherapy and Exercise Therapy. 2021;98(3):5‑10. (In Russ.)
https://doi.org/10.17116/kurort2021980315

Подписка 2026 Вопросы курортологии, физиотерапии и лечебной физической культуры (Problems of Balneology, Physiotherapy and Exercise Therapy)

Использование инфографики авторами научных работ

Close metadata

OBJECTIVE

The rationale for the use of infrared (IR) radiation with terahertz (THz) modulation in the complex treatment of patients in the acute period of IS.

MATERIAL AND METHODS

The results of transcranial application of IR radiation with THz modulation in 112 patients in the acute period of IS are presented. In the main group (38 patients) the infrared radiation with THz modulation was used on the projection of the IS focus in addition to basic drug therapy; in the control group (37 patients) — basic drug therapy; in the placebo group (37 patients) the physiotherapy was mimicked. The data of neurological status and neuro-functional indicators were assessed using the NIHSS, MMSE, Rankin, and Rivermid scales. Cerebral blood flow was examined using duplex scanning of brachiocephalic vessels.

RESULTS

The inclusion in the complex treatment of IR radiation with THz modulation on the projection of the IS focus in the acute period contributed to a significant regression of neurological deficit, a complete recovery of cognitive functions and an increase in daily activity due to the restoration of adequate blood supply on the side of the affected hemisphere.

CONCLUSION

A pathogenesis justified method of treating acute IS is proposed which can increase the effectiveness of early neurorehabilitation measures. An early improvement in cerebral hemoperfusion led to the creation of optimal conditions for the survival of neural structures and the preservation of their functional activity that demonstrated the neuroprotective feasibility of early inclusion of IR radiation with THz modulation in the complex treatment of patients in the acute period of IS.

Keywords:

ischemic stroke

transcranial physiotherapy

infrared radiation

terahertz radiation

neuroprotection

Authors:

Kiriyanova V.V.

St. Petersburg State Pediatric Medical University

ORCID: 0000-0003-2412-7041

Molodovskaya N.V.

Semashko City Hospital No. 38

Potapchuk A.A.

Academician I.P. Pavlov First Saint Petersburg State Medical University

Zharova E.N.

I.I. Mechnikov Northwestern State Medical University

Received:

02.09.2020

Accepted:

17.01.2021

Close metadata

References:

Kir’janova VV, Molodovskaya NV. Nejroprotektornye jeffekty infrakrasnogo izluchenija s teragercevoj moduljaciej v ostrom periode ishemicheskogo insul’ta. Fizioterapevt. 2019;5:21-25. (In Russ.).
Koval’chuk VV, Skoromets AA, Barantsevich ER, Minnullin TI, Molodovskaya NV, Nesterin KV. Vozmozhnye puti normalizatsii kognitivnykh funktsiy i psikhoemotsional’nogo sostoyaniya, a takzhe uluchsheniya kachestva zhizni u patsientov posle insul’ta. Nervnye bolezni. 2017;1:32-40. (In Russ.).
Koval’chuk VV, Gusev AO, Barancevich ER, Bakirova DA, Nesterin KV, Molodovskaya NV, Agybaeva AB. Pacient posle sosudistoj katastrofy: principy reabilitaciii osobennosti vedenija. Consilium Medicum. 2017;9(19):18-25. (In Russ.).
Odinak MM, Yanishevskiy SN, Voznyuk IA, Tsygan NV. Neyromediatornaya terapiya insul’ta: rezul’taty nekotorykh issledovaniy. Effektivnaya farmakoterapiya. 2013;45:6-13. (In Russ.).
Kir’janova VV, Molodovskaya NV, Zharova EN. Morfologicheskie aspekty primenenija transkranial’nyh metodov fizioterapii v rannem periode ishemicheskogo insul’ta. Vestnik fizioterapii i kurortologii. 2019;2:34-40. (InRuss.).
Zanin SA, Kade AKh, Trofimenko AI, Malysheva AV. Gistologicheskoe obosnovanie effektivnosti TES-terapii pri eksperimental’nom ishemicheskom insul’te. Sovremennye problem nauki i obrazovaniya. 2015;1(1):1343. (InRuss.).
Shertaev MM, Ibragimov UK, Ikramova SH, Yakubova FT, Ibragimov KU. Morfologicheskie izmeneniya v tkanyakh golovnogo mozga pri eksperimental’noy ishemii. Vestnik Novosibirskogo gosudarstvennogo pedagogicheskogo universiteta. 2015;1(23):72-79. (In Russ.). https://doi.org/10.15293/2226-3365.1501.07
Kolomencev SV, Odinak MM, Voznyuk IA, Cygan NV, Yanishevskij SN, Golohvastov SYu, Andreev RV, Emelin AYu, Pomet’ko DV. Ishemicheskiy insul’t u statsionarnogo patsienta. Sovremennyy vzglyad na sostoyanie problemy. Vestnik Rossiyskoy Voenno-meditsinskoy akademii. 2017;2(58):206-212. (In Russ.).
Koval’chuk VV, Zueva IB, Barancevich ER, Bakirova DA, Nesterin KV, Galkin AS, Molodovskaya NV, Ertman KA, Rulis LK, Stepanenko MA. Patsient posle insul’ta. Osobennosti vedeniya i printsipy reabilitatsii. Effektivnaya farmakoterpiya. 2018;24:68-81. (In Russ.).
Bagraev NT, Kljachkin LE, Maljarenko AM, Novikov BA. Pribory infrakrasnoj i teragercevoj nanojelektroniki v biologiii medicine. Innovacii. 2007;12(110):99-104. (In Russ.).
Beckij OV, Koz’min AS, Fajkin VV, Yaryomenko YuG. Analiz biofizicheskih mekhanizmov vozdejstviya nizkointensivnyh elektromagnitnyh voln v krajnevysokochastotnom i teragercevom diapazonah chastot. Biomedicinskaya radioelektronika. 2014;5:29-37. (InRuss.).
Duka MV, Dvoretskaya LN, Balbekin NS, Khodzitskii MK, Chivilikhin SA, Smolyanskaya OA. Numericaland experimental studies of mechanisms underlying the effect of pulsed broadband terahertz radiation on nerve cells. Quantum Electronics. 2014;44(8):707. https://doi.org/10.1070/QE2014v044n08ABEH015486
Kirichuk VF, Ivanov AN, Sahan’ MA. Sposob profilaktiki narushenij perfuzii tkanej golovnogo mozga v usloviyah ostroj eksperimental’noj ishemii. Patent RF na izobretenie No. 2496534/27.10.2013. Byul. No. 30. Accessed July 07, 2020. (InRuss.). https://findpatent.ru/patent/249/2496534.html
Kirichuk VF, Antipova ON, Velikanov VV, Velikanova TS. Sposob vosstanovleniya izmenennoj linejnoj skorosti krovotoka v magistral’nyh arteriyah. Patent RF na izobretenie No. 2499619/27.11.2013. Byul. No. 33. Accessed July 07, 2020. (In Russ.). https://findpatent.ru/patent/249/2499619.html
Kirichuk VF, Cymbal AA. Primenenie elektromagnitnyh voln teragercovogo diapazona dlya korrekcii funkcij gemostaza. Medicinskaya tekhnika. 2010;1(259):12-16. (In Russ.).
Oron A, Oron U, Streeter J, De Taboada L, Alexandrovich A, Trembovler V, Shohami E. Near infrared transcranial laser therapy applied at various modes to mice following traumatic brain injury significantly reduces long-term neurological deficits. J Neurotrauma. 2012;29(2):401-407. https://doi.org/10.1089/neu.2011.2062