Abstract Background. The problem of ensuring long-term well-being and high quality of life for older women is becoming the most important goal of modern medicine. The initial presence of metabolic syndrome complicates the course of menopause; and menopausal hormone therapy cannot always be used. The urgency for finding the effective ways of non-drug correction of menopausal disorders in this category of patients is obvious. Aim. To comparatively evaluate the effectiveness of complex non-drug programs in the correction of psychoemotional disorders of menopause in patients with metabolic syndrome. Material and methods. A total of 330 women aged 45—50 years with menopausal syndrome in the presence of metabolic syndrome were examined. The examinees were randomized into 5 groups. All the patients received conventional treatment. A study and comparison groups used exercise therapy, drank mineral water, and additionally took multivitamins and minerals. The physiotherapeutic component of therapeutic complexes was represented by various combinations of factors (vibrotherapy, chromotherapy, melotherapy, aromatherapy, and aeroionotherapy). The control group received conventional treatment only. The degree of severity of psychoemotional disorders was estimated before and 3 and 6 months after treatment via the modified Kupperman menopausal index (MMI), the Spielberger—Khanin Trait Anxiety Inventory, and the Hamilton Depression Rating Scale. Results. Psychoemotional symptoms were most significantly reduced (1.5-fold) after 6 months of treatment in patients with mild disorders when the complexes, including vibrotherapy, were applied. In patients with moderate disorders, the simultaneous use of vibrotherapy, chromotherapy, melotherapy, aromatherapy, and aeroionotherapy promoted the maximum regression of psychoemotional symptoms (by 47.3%) (p<0.05). The application of the conventional approach was observed to aggravate psychoemotional disorders. Conclusion. Complex non-drug programs, including physiotherapy, effectively relieve perimenopausal psychoemotional disorders in patients with metabolic syndrome. Vibrotherapy substantially improves the results of treatment. Moderate psychoemotional disorders need the complex program to be applied simultaneously with vibrotherapy, chromotherapy, melotherapy, aromatherapy, and aeroionotherapy.