Investigations into the relationship between respiratory disorders and excessive body weight in the adolescents presenting with bronchial asthma treated based at a specialized health resort 
facility

Mokina N.A.; Iashkov A.V.; Gudkova M.A.; Samoĭlova E.N.; Goriainov Iu.A.

doi:https://doi.org/10.17116/kurort2015327-34

Mokina N.A.

GBOU VPO "Samarskiĭ gosudarstvennyĭ meditsinskiĭ universitet" Minzdrava Rossii;
GBUZ "Samarskiĭ oblastnoĭ detskiĭ sanatoriĭ "Iunost'"

SPIN RSCI: 2273-3667
Scopus AuthorID: 6506137856
ORCID: 0000-0001-5009-1623

Iashkov A.V.

GBOU VPO "Samarskiĭ gosudarstvennyĭ meditsinskiĭ universitet" Minzdrava Rossii

Gudkova M.A.

GBUZ "Samarskiĭ oblastnoĭ detskiĭ sanatoriĭ "Iunost'"

Samoĭlova E.N.

GBUZ "Samarskiĭ oblastnoĭ detskiĭ sanatoriĭ "Iunost'"

Goriainov Iu.A.

GBUZ Samarskoĭ oblasti "Koshkinskaia TsRB"

Investigations into the relationship between respiratory disorders and excessive body weight in the adolescents presenting with bronchial asthma treated based at a specialized health resort facility

Authors:

Mokina N.A., Iashkov A.V., Gudkova M.A., Samoĭlova E.N., Goriainov Iu.A.

More about the authors

Journal: Problems of Balneology, Physiotherapy and Exercise Therapy. 2015;92(3): 27‑34

DOI: 10.17116/kurort2015327-34

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To cite this article:

Mokina NA, Iashkov AV, Gudkova MA, Samoĭlova EN, Goriainov IuA. Investigations into the relationship between respiratory disorders and excessive body weight in the adolescents presenting with bronchial asthma treated based at a specialized health resort facility. Problems of Balneology, Physiotherapy and Exercise Therapy. 2015;92(3):27‑34. (In Russ.)
https://doi.org/10.17116/kurort2015327-34

Подписка 2026 Вопросы курортологии, физиотерапии и лечебной физической культуры (Problems of Balneology, Physiotherapy and Exercise Therapy)

Использование инфографики авторами научных работ

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Abstract:

A total of 71 patients with bronchial asthma (BA) were examined and treated based at a specialized health facility of whom 43 ones presented with mild asthma and 26 patients with moderately severe asthma in remission. The median age of the patients was 12,04±2,08 years. Spirometry parameters: MOS50, MOS75, and PSV, proved to be of high informative value combined with high enough sensitivity and specificity. The significant difference between the groups as a whole (p<0,05) were documented based on the serum leptin levels that were higher in the overweight patients and especially in the girls (p<0,05). The leptin level was a similarly sensitive/specific (AUROC 0.5) and informative (SCDFC >0.5) parameter which confirms its diagnostic value given it is employed in combination with overweight for the evaluation of the status of the patients suffering from asthma. Negative linear and non-parametric correlation between the functional parameters and the serum leptin levels in the overweight patients with bronchial asthma suggests that the enhanced leptin concentration may serve as a marker of strong obstruction and severe inflammation at all levels of the respiratory tract in the patients presenting with a combination of the two conditions.

Keywords:

bronchial asthma

overweight

spirometry

serum leptin

Authors:

Mokina N.A.

GBOU VPO "Samarskiĭ gosudarstvennyĭ meditsinskiĭ universitet" Minzdrava Rossii;
GBUZ "Samarskiĭ oblastnoĭ detskiĭ sanatoriĭ "Iunost'"

SPIN RSCI: 2273-3667
Scopus AuthorID: 6506137856
ORCID: 0000-0001-5009-1623

Iashkov A.V.

GBOU VPO "Samarskiĭ gosudarstvennyĭ meditsinskiĭ universitet" Minzdrava Rossii

Gudkova M.A.

GBUZ "Samarskiĭ oblastnoĭ detskiĭ sanatoriĭ "Iunost'"

Samoĭlova E.N.

GBUZ "Samarskiĭ oblastnoĭ detskiĭ sanatoriĭ "Iunost'"

Goriainov Iu.A.

GBUZ Samarskoĭ oblasti "Koshkinskaia TsRB"

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References:

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