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Dobretsov K.G.

Research Institute of Olfaction and Olfactory Pathology

Kashirskiy D.V.

Federal State Autonomous Educational Institution of Higher Education «Russian State Humanitarian University»;
Federal State Budgetary Educational Institution of Higher Education «Financial University under the Government of the Russian Federation»

Sazhin A.V.

Limited Liability Company. «LOR Plus Medical Center»

Sazhina G.A.

Limited Liability Company. «LOR Plus Medical Center»

The role of Inflasinusans in the treatment of acute rhinosinusitis

Authors:

Dobretsov K.G., Kashirskiy D.V., Sazhin A.V., Sazhina G.A.

More about the authors

Journal: Russian Bulletin of Otorhinolaryngology. 2025;90(4): 64‑71

Read: 485 times


To cite this article:

Dobretsov KG, Kashirskiy DV, Sazhin AV, Sazhina GA. The role of Inflasinusans in the treatment of acute rhinosinusitis. Russian Bulletin of Otorhinolaryngology. 2025;90(4):64‑71. (In Russ.)
https://doi.org/10.17116/otorino20259004164

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References:

  1. Otorinolaringologiya. Natsional’noe rukovodstvo. Palchun VP, ed. M.: GEOTAR-Media; 2008. (In Russ.).
  2. Kryukov AI, Studenyi ME, Artemyev ME, Chumakov PL, Rynkov DA, Gorin DS.Treatment of patients with rhinosinusitis: possibilities of conservative and operative treatment. Meditsinskij sovet. 2012;11:92-96. (In Russ.).
  3. The consensus on breathing difficulties in children. Nasal obstruction is a multidisciplinary problem. Resolution of the Council of Experts. Voprosy prakticheskoj pediatrii. 2021;16(6):149-160. (In Russ.).
  4. Nosulya EV, Kryukov AI, Kunelskaya NL, Kim IA. Acute sinusitis: current issues of terminology and diagnostics. Russian Bulletin of Otorhinolaryngology. 2021;86(3):72-77. (In Russ.). https://doi.org/10.17116/otorino20218603172
  5. Svistushkin VM, Nikiforova GN, Toldanov AV, Zolotova AV, Shevchik EA, Nikiforova AN. Possibilities of using a modern herbal medicinal product in the treatment of patients with acute viral rhinosinusitis. Russian Bulletin of Otorhinolaryngology. 2023;88(5):49-57. (In Russ.). https://doi.org/10.17116/otorino20238805149
  6. Mammadova RF, Babaev MS. Study of optimal options for the extraction of tannins of creeping thyme in the flora of Azerbaijan. Sel’skoe khozyajstvo. 2020;1:15-24. (In Russ.).
  7. Geppe NA, Glukhova MV, Denisova AR, Kolosova NG, Shatalina SI, Shahnazarova MD. The effectiveness of mucolytic therapy in acute respiratory diseases in children. Doctor.Ru. Pediatrics. 2015;13(114):59-63. (In Russ.).
  8. Zakay-Rones Z, Thom E, Wollan T, Wadstein J. Randomized study of the efficacy and safety of oral elderberry extract in the treatment of influenza A and B virus infections. Journal of International Medical Research. 2004;32(2):132-140. 
  9. Tatarinov VV, Orlova SV, Nikitina EA, Prokopenko E V, Vodolazkaya AN, Pigareva YuA, Paliy KV. Dihydroquercetin as a potential immunonutrient in the complex therapy of COVID-19. Meditsinskij alfavit. 2021;22:28-32. (In Russ.). https://doi.org/10.33667/2078-5631-2021-21-28-32
  10. Ostrye respiratornye virusnye infektsii (ORVI) u vzroslykh. Klinicheskie rekomendatsii. 2021. (In Russ.). Accessed August 05, 2025. https://cr.minzdrav.gov.ru/schema/724_1
  11. Van Straten M, Josling P. Preventing the common cold with a vitamin C supplement: a double-blind, placebo-controlled survey. Advances in Therapy. 2002;19(3):151-159.  https://doi.org/10.1007/BF02850271
  12. Hemilä H, Chalker E. Vitamin C for preventing and treating the common cold. The Cochrane Database of Systematic Reviews. 2013;(1): CD000980. https://doi.org/10.1002/14651858.CD000980.pub4
  13. Sasazuki S, Sasaki S, Tsubono Y, Okubo S, Hayashi M, Tsugane S. Effect of vitamin C on common cold: randomized controlled trial. European Journal of Clinical Nutrition. 2006;60(1):9-17.  https://doi.org/10.1038/sj.ejcn.1602261
  14. Sankova MV, Kytko OV, Dydykina IS, Chirikov VV, Lopatina VI, Markina AD. Improving zinc supply as a pathogenetically based platform for maintaining immunity during the SARS-CoV-2 pandemic. Voprosy` pitaniya. 2021;90(2):26-39. (In Russ.).
  15. Prasad AS, Fitzgerald JT, Bao B, Beck FW, Chandrasekar PH. Duration of symptoms and plasma cytokine levels in patients with the common cold treated with zinc acetate. A randomized, double-blind, placebo-controlled trial. Annals of Internal Medicine. 2000;133(4):245-252.  https://doi.org/10.7326/0003-4819-133-4-200008150-00006
  16. Aiba T, Sugiura M, Mori J, Matsumoto K, Tomiyama K, Okuda F, Nakai Y. Effect of zinc sulfate on sensoryneural olfactory disorder. Acta Oto-Laryngologica. Supplementum. 1998;538:202 -204.  https://doi.org/10.1080/00016489850182936
  17. Morozova SV, Keda LA. A rational approach to the treatment of acute rhinosinusitis in combination with dysosmia. Meditsinskij sovet. 2020;6:7-13. (In Russ.).
  18. Dobretsov KG, Kashirsky DV. Assessment of the sense of smell in acute sinusitis. Russian Rhinology. 2025;33(1):6-11. (In Russ.).
  19. Racional`noe pitanie. Rekomenduemy`e urovni potrebleniya pishhevy`x i biologicheski aktivny`x veshhestv. Metodicheskie rekomendacii MP 2.3.1.19150-04. M, 2004. Accessed August 05,2025. (In Russ.). https://ohranatruda.ru/upload/iblock/5e9/4293846547.pdf
  20. Dobretsov KG, Kashirsky DV. The study of the threshold of smell using the Russian version of the Sniffing Sticks test. Rossijskaya rinologiya. 2024;1:6-10. (In Russ.).
  21. Oleszkiewicz A, Schriever VA, Croy I, Hähner A, Hummel T. Updated Sniffin’ Sticks normative data based on an extended sample of 9139 subjects. European Archives of Oto-Rhino-Laryngology. 2019;276(3):719-728.  https://doi.org/10.1007/s00405-018-5248-1
  22. Dobretsov KG, Kashirsky DV. Questionnaire of olfactory dysfunction: Russian-language adaptation of the Olfactory Questionnaire methodology (OQ, Ji-woong Kim, etc.). Rossijskaya rinologiya. 2023;31(3):201-205. (In Russ.). https://doi.org/10.17116/rosrino202331031201

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