Assessment of olfactory level in acute sinusitis

Dobretsov K.G.; Kashirsky D.V.

doi:https://doi.org/10.17116/rosrino2025330116

Dobretsov K.G.

Russian State Social University

SPIN RSCI: 1017-7664
Scopus AuthorID: 24477018000
ORCID: 0000-0002-7468-9117

Kashirsky D.V.

Russian State Social University;
Financial University under the Government of the Russian Federation

SPIN RSCI: 4389-5243
Scopus AuthorID: 6506320819
ResearcherID: AAK-2382-2020
ORCID: 0000-0002-8251-2653

Assessment of olfactory level in acute sinusitis

Authors:

Dobretsov K.G., Kashirsky D.V.

More about the authors

Journal: Russian Rhinology. 2025;33(1): 6‑11

DOI: 10.17116/rosrino2025330116

Read: 882 times

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To cite this article:

Dobretsov KG, Kashirsky DV. Assessment of olfactory level in acute sinusitis. Russian Rhinology. 2025;33(1):6‑11. (In Russ.)
https://doi.org/10.17116/rosrino2025330116

Подписка 2026 Российская ринология (Russian Rhinology)

Использование инфографики авторами научных работ

OBJECTIVE

To study the olfactory level in patients with acute sinusitis.

PATIENTS AND METHODS

A number of patients equal 67 with acute sinusitis aged 18—70 years was examined: 35 (52.2%) women and 32 (47.8%) men. An endoscopic examination of the olfactory recess was performed to analyze the mechanism of hyposmia. The Russian version of the Sniffin’ Sticks test was used to assess the olfactory thresholds.

RESULTS AND DISCUSSION

It has been revealed during the study that hyposomia is a frequent symptom of acute sinusitis (83.6%). In 52.2% of cases, conductive hyposmia has been determined in patients, neurosensory — in 31.3% of subjects. Olfaction was reduced more in men than in women. However, these data were not statistically significant. The degree of hyposmia was significantly higher in patients with inflammatory changes of the mucosa in the area of the olfactory recess (5.5 versus 6.4), which may correlate with the severity of acute sinusitis.

CONCLUSION

The olfactory level determination in patients with acute sinusitis is an important diagnostic criterion that allows to assess the severity of sinusitis and to choose effective treatment tactics. The Russian version of the Sniffin’ Sticks test is a simple and standardized method that can be used in the clinical practice of otorinolaryngologists.

Keywords:

hyposmia

olfactory dysfunction

Russian version of the Sniffin’ Sticks test

RVSS

threshold evaluation of olfaction

acute sinusitis

olfactory recess

inflammation

conductive hyposmia

neurosensory hyposmia

olfaction

Authors:

Dobretsov K.G.

Russian State Social University

SPIN RSCI: 1017-7664
Scopus AuthorID: 24477018000
ORCID: 0000-0002-7468-9117

Kashirsky D.V.

Russian State Social University;
Financial University under the Government of the Russian Federation

SPIN RSCI: 4389-5243
Scopus AuthorID: 6506320819
ResearcherID: AAK-2382-2020
ORCID: 0000-0002-8251-2653

Received:

25.01.2024

Accepted:

25.03.2024

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References:

Otorhinolaryngology. National leadership. Ed. V.P. Palchuna. Moscow: GEOTAR-Media; 2008. (In Russ.).
Deems DA, Doty RL, Settle RG, Moore-Gillon V, Shaman P, Mester AF, Kimmelman CP, Brightman VJ, Snow JB Jr. Smell and taste disorders, a study of 750 patients from the University of Pennsylvania Smell and Taste Center. Arch Otolaryngol Head Neck Surg. 1991;117(5):519-528. https://doi.org/10.1001/archotol.1991.01870170065015
Mott AE, Leopold DA. Disorders in taste and smell. Med Clin North Am. 1991;75:1321-1353.
Seiden AM, Duncan HJ. The diagnosis of a conductive olfactory loss. Laryngoscope. 2001;111:9-14.
Seiden AM. Postviral olfactory loss. Otolaryngol Clin North Am. 2004;37(6):1159-1166.
Lane AP, Zweiman B, Lanza DC, Swift D, Doty R, Dhong HJ, Kennedy DW. Acoustic rhinometry in the study of the acute nasal allergic response. Ann Otol Rhinol Laryngol. 1996;105(10):811-818. https://doi.org/10.1177/000348949610501009
Klimek L, Eggers G. Olfactory dysfunction in allergic rhinitis is related to nasal eosinophilic inflammation. J Allergy Clin Immunol. 1997;100:158-164.
Hox V, Bobic S, Callebaux I, Jorissen M, Hellings PW. Nasal obstruction and smell impairment in nasal polyp disease: correlation between objective and subjective parameters. Rhinology. 2010;48:426-432.
Kanaya K, Kondo K, Suzukawa K, Sakamoto T, Kikuta S, Okada K, Yamasoba T. Innate immune responses and neuroepithelial degeneration and regeneration in the mouse olfactory mucosa induced by intranasal administration of Poly(I:C). Cell Tissue Res. 2014;357(1):279-299. https://doi.org/10.1007/s00441-014-1848-2
Henkin RI, Schmidt L, Velicu I. Interleukin 6 in hyposmia. JAMA Otolaryngol Head Neck Surg. 2013;139:728-734.
Stevens MH. Steroid-dependent anosmia. Laryngoscope. 2001;111:200-203.
Alobid I, Benítez P, Cardelús S, de Borja Callejas F, Lehrer-Coriat E, Pujols L, Picado C, Mullol J. Oral plus nasal corticosteroids improve smell, nasal congestion, and inflammation in sino-nasal polyposis. Laryngoscope. 2014;124:50-56. https://doi.org/10.1002/lary.24330
Banglawala SM, Oyer SL, Lohia S, Psaltis AJ, Soler ZM, Schlosser RJ. Olfactory outcomes in chronic rhinosinusitis with nasal polyposis after medical treatments: A systematic review and meta-analysis. Int Forum Allergy Rhinol. 2014;4:986-994.
Носуля Е.В., Крюков А.И., Кунельская Н.Л., Ким И.А. Острый синусит: актуальные вопросы терминологии и диагностики. Вестник оториноларингологии. 2021;86(3):72-77.
Nosulya EV, Kryukov AI, Kunelskaya NL, Kim IA. Acute sinusitis: current issues of terminology and diagnosis. Bulletin of otorhinolaryngology. 2021;86(3):72-77. (In Russ.). https://doi.org/10.17116/otorino20218603172
Dobretsov KG, Kashirsky DV. Studying the threshold of smell using the Russian version of the Sniffin Stix test. Russian rhinology. 2024;32(1):6-10. (In Russ.). https://doi.org/10.17116/rosrino2024320116
Oleszkiewicz A, Schriever VA, Croy I, Hähner A, Hummel T. Updated Sniffin’ Sticks normative data based on an extended sample of 9139 subjects. Eur Arch Otorhinolaryngol. 2019 Mar;276(3):719-728.
Sorokowski P, Karwowski M, Misiak M, Marczak MK, Dziekan M, Hummel T, Sorokowska A. Sex Differences in Human Olfaction: A Meta-Analysis. Front Psychol. 2019;10:1-10.
Yanov YuK, Ryazantsev SV, Strachunsky LS, Stetsyuk OU, Kamanin EI, Tarasov AA, Otvagin IV, Kryukov AI, Bogomilsky MR. Practical recommendations for antibacterial therapy of sinusitis: a manual for doctors. Clinical microbiology and antimicrobial chemotherapy. 2003;2(5):167-174. (In Russ.).