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Krukov A.I.

Sverzhevsky Moscow Scientific and Practical Othorhinolaryngology Center, Moscow

Gurov A.V.

Kafedra otorinolaringologiiRNIMU im. N.I. Pirogova Minzdravsotsrazvitiia Rossii, Moskva

Yushkina M.A.

N.I. Pirogov Russian National Research Medical University, Russian Ministry of Health, Moscow, Russia, 117997

Izotova G.N.

Moskovskiĭ nauchno-prakticheskiĭ tsentr otorinolaringologii im. L.I. Sverzhevskogo Departamenta zdravookhraneniia, Moskva, Rossiia, 117152

Peculiarities of clinical course of inflammatory diseases of the oropharynx of various etiologies and possibilities of local therapy

Authors:

Krukov A.I., Gurov A.V., Yushkina M.A., Izotova G.N.

More about the authors

Journal: Russian Bulletin of Otorhinolaryngology. 2019;84(5): 68‑72

DOI: 10.17116/otorino20198405168

Views: 5767

Downloaded: 110

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To cite this article:

Krukov AI, Gurov AV, Yushkina MA, Izotova GN. Peculiarities of clinical course of inflammatory diseases of the oropharynx of various etiologies and possibilities of local therapy. Russian Bulletin of Otorhinolaryngology. 2019;84(5):68‑72. (In Russ.)
https://doi.org/10.17116/otorino20198405168

Подписка 2025 (Russian Bulletin of Otorhinolaryngology)
 
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The article covers the problems of diagnosis and treatment of inflammatory diseases of the oropharynx. The authors consider the main nosological forms of focal inflammation in the throat, discuss the role of β-hemolytic streptococcus group A in the genesis of angina and chronic tonsillitis and their complications. The authors discuss the influence of irritants — smoking, alcohol, cold air, gastroesofareal reflux on the development of chronic inflammation of the oropharynx mucosa. Leading clinical symptoms in oropharyngeal diseases and the main methods of their treatment are presented. The authors conclude that the most effective treatment of focal inflammation in the throat is the use of combined topical drugs. As a choice for local therapy of pharyngeal diseases, the authors offer a combined drug Doritiricin, effectively and safely relieving pain syndrome and local inflammatory response.

Keywords:

inflammation
pharynx
local therapy
sore throat
Doritiricin

Authors:

Krukov A.I.

Sverzhevsky Moscow Scientific and Practical Othorhinolaryngology Center, Moscow

Gurov A.V.

Kafedra otorinolaringologiiRNIMU im. N.I. Pirogova Minzdravsotsrazvitiia Rossii, Moskva

Yushkina M.A.

N.I. Pirogov Russian National Research Medical University, Russian Ministry of Health, Moscow, Russia, 117997

Izotova G.N.

Moskovskiĭ nauchno-prakticheskiĭ tsentr otorinolaringologii im. L.I. Sverzhevskogo Departamenta zdravookhraneniia, Moskva, Rossiia, 117152

List of references:

  1. Nikiforova GN, Volkova KB. New possibilities for the treatment of inflammatory diseases of the throat. Consilium Medicum. 2015;11:103-107. (In Russ.)
  2. Ryazancev SV, Kocherovec VI. Etiopatogeneticheskaya terapiya zabolevanij verhnih dyhatel’nyh putej i uha. Metodicheskie rekomendacii. SPb. 2008. (In Russ.)
  3. Pal’chun VT, Krjukov AI, Magomedov MM. Rukovodstvo po ochagovoj infekcii v otorinolaringologii. M.: GEOTAR-Media; 2015. (In Russ.)
  4. Pal’chun VT, Luchihin LA, Krjukov AI. Vospalitel’nye zabolevanija glotki. M.: GEOTAR-Media; 2007. (In Russ.)
  5. Pal’chun VT, Gurov AV, Aksenova AV, Guseva OA. Modern ideas about toxic-allergic manifestations of chronic tonsillar pathology, its etiological and pathogenetic role in the emergence and course of common diseases. Vestnik Otorinolaringologii. 2012;2:5-12. (In Russ.)
  6. Alqanatish J, Alfadhel A, Albelali A, Alqahtani D. Acute rheumatic fever diagnosis and management: Review of the global implications of the new revised diagnostic criteria with a focus on Saudi Arabia. J Saudi Heart Assoc. 2019;31(4):273-281. https://doi.org/10.1016/j.jsha.2019.07.002
  7. Kosjakov SYa, Loranskaya ID, Angotoeva IB, Muldasheva AA. Laryngopharyngeal reflux: yesterday, today, tomorrow. Medicinskij Sovet. 2016;6:78-80. (In Russ.)
  8. Palm J, Fuchs K, Stammer H, Schumacher-Stimpfl A, Milde J; DoriPha investigators. Efficacy and safety of a triple active sore throat lozenge in the treatment of patients with acute pharyngitis: Results of a multi-centre, randomised, placebo-controlled, double-blind, parallel-group trial (DoriPha). Int J Clin Pract. 2018;72(12):13272. Epub 2018 Oct 17. https://doi.org/10.1111/ijcp.13272
  9. Lang C, Staiger C. Tyrothricin- An underrated agent for the treatment of bacterial skin infections and superficial wounds? Pharmazie. 2016;71(6):299-305.
  10. Eberhardt R, Maier-Bosse I, Schlauch W. Halsschmerzen bei akuter Pharyngitis. Deutsche Apotheker Zeitung. 2004;144(7):753-754.
  11. Scholten T, Pautler M, Kober G. Dorithricin bei akuter Pharyngitis. Deutsche Apotheker Zeitung. 2005;145(1):81-82.
  12. Palm J, Fuchs K, Stammer H, Schumacher-Stimpfl A, Milde J Efficacy and safety of a triple active sore throat lozenge in the treatment of patients with acute pharyngitis: Results of a multi-centre, randomised, placebo- controlled, double-blind, parallel-group trial (DoriPha). Int J Clin Pract. 2018;72:13272.

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