The objective of the present study was to evaluate the state of the vegetative nervous system in pregnant women both healthy and presenting with vasomotor rhinitis. The initial vegetative tone was determined based on the table for its instant diagnostics. The state of the vegetative nervous system was assessed in 116 pregnant women with vasomotor rhinitis (29 in the first trimester, 33 in the second trimester, and 54 in the third trimester) and in 48 healthy pregnant women (21 in the first trimester, 14 in the second trimester, and 13 in the third trimester). It was shown that the prevailing activity of the parasympathetic component of the vegetative nervous system appears to be the leading risk factor responsible for the development of vasomotor rhinitis in pregnant women in I, II, and III trimesters. It accounts for the occurrence of this disease in 85.2% of the women during the first trimester, in 72.7% and 70.4% during the second and third trimesters respectively).