The differential approach to the treatment of exudative otitis media with the use of mucosal immunocorrection

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Ochirov D.D.

Tomskiĭ filial FGU "Nauchno-klinicheskiĭ tsentr otorinolaringologii FMBA Rossii"

Shcherbik N.V.

Tomskiĭ filial FGU "Nauchno-klinicheskiĭ tsentr otorinolaringologii FMBA Rossii";
Kafedra otorinolaringologii Sibirskogo gosudarstvennogo meditsinskogo universiteta, Tomsk

Kologrivova E.N.

Kafedra otorinolaringologii;
Kafedra immunologii i allergologii Sibirskogo gosudarstvennogo meditsinskogo universiteta, Tomsk

The differential approach to the treatment of exudative otitis media with the use of mucosal immunocorrection

Authors:

Ochirov D.D., Shcherbik N.V., Kologrivova E.N.

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Journal: Russian Bulletin of Otorhinolaryngology. 2012;77(5): 65‑68

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To cite this article:

Ochirov DD, Shcherbik NV, Kologrivova EN. The differential approach to the treatment of exudative otitis media with the use of mucosal immunocorrection. Russian Bulletin of Otorhinolaryngology. 2012;77(5):65‑68. (In Russ.)

Подписка 2025 (Russian Bulletin of Otorhinolaryngology)

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The objective of the present study was to improve the efficacy of the treatment of the patients suffering from exudtaive otitis media (EOM). A total of 75 patients presenting with EOM were allocated to 2 groups. In one of them (n=36) the patients were treated using conventional therapeutic modalities, in the other one (n=39) with the use of a local immunomodulator (a 0.04% synthetic tetradecapeptide solution). The local application of the immunocorrective agent has demonstrated its normalizing action on the parameters of both local and systemic immunity. It is concluded that the adequate and timely treatment with the use of synthetic tetradecapeptide reduces the probability of relapse and chronization of the pathological process which not infrequently allows the surgical intervention to be avoided.

Keywords:

exudative otitis media

immunocorrection

cytokines

Authors:

Ochirov D.D.

Tomskiĭ filial FGU "Nauchno-klinicheskiĭ tsentr otorinolaringologii FMBA Rossii"

Shcherbik N.V.

Tomskiĭ filial FGU "Nauchno-klinicheskiĭ tsentr otorinolaringologii FMBA Rossii";
Kafedra otorinolaringologii Sibirskogo gosudarstvennogo meditsinskogo universiteta, Tomsk

Kologrivova E.N.

Kafedra otorinolaringologii;
Kafedra immunologii i allergologii Sibirskogo gosudarstvennogo meditsinskogo universiteta, Tomsk

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