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Efendieva M.Kh.

Research Institute of Eye Disease, 11 A, B, Rossolimo St., Moscow, Russia, 119021

Budzinskaia M.V.

FGBU "Nauchno-issledovatel'skiĭ institut glaznykh bolezneĭ" RAMN, Moskva

Kadyshev V.V.

Research Centre for Medical Genetics, 1 Moskvorechie St., Moscow, Russian Federation, 115478

Zinchenko R.A.

Research Center for Medical Genetics, 1 Moskvorech’e St., Moscow, Russian Federation, 115478;
Pirogov Russian National Research Medical University, 1 Ostrovityanova St., Moscow, Russian Federation, 117997

Savochkina O.A.

Research Institute of Eye Diseases, 11A Rossolimo St., Moscow, Russian Federation, 119021

Pupysheva A.D.

I.M. Sechenov First Moscow State Medical University, Department of Ophthalmology, 8-2 Trubetskaya St., Moscow, Russian Federation, 119991

Molecular and genetic aspects of age-related macular degeneration and glaucoma (in Russian only)

Authors:

Efendieva M.Kh., Budzinskaia M.V., Kadyshev V.V., Zinchenko R.A., Savochkina O.A., Pupysheva A.D.

More about the authors

Journal: Russian Annals of Ophthalmology. 2019;135(3): 121‑127

DOI: 10.17116/oftalma2019135031121

Views: 1646

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To cite this article:

Efendieva MKh, Budzinskaia MV, Kadyshev VV, Zinchenko RA, Savochkina OA, Pupysheva AD. Molecular and genetic aspects of age-related macular degeneration and glaucoma (in Russian only). Russian Annals of Ophthalmology. 2019;135(3):121‑127. (In Russ.)
https://doi.org/10.17116/oftalma2019135031121

Подписка 2025 (Russian Annals of Ophthalmology)
 
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In most cases, age-related macular degeneration (AMD) and glaucoma are considered multi-factor diseases that lead to irreversible blindness in senior population of developed countries. Among different types of these diseases, around 5% are monogenic. Studying their molecular and genetic aspects can lay the basis for improvement of diagnostic methods, prognosis of the risks of development, manner of progression and treatment outcomes, as well as creation of new therapy methods. The article reviews modern understanding of the etiopathogenesis of AMD and glaucoma and describes their interrelations.

Keywords:

age-related macular degeneration
primary open angle glaucoma
genetic polymorphism
pharmacogenetics

Authors:

Efendieva M.Kh.

Research Institute of Eye Disease, 11 A, B, Rossolimo St., Moscow, Russia, 119021

Budzinskaia M.V.

FGBU "Nauchno-issledovatel'skiĭ institut glaznykh bolezneĭ" RAMN, Moskva

Kadyshev V.V.

Research Centre for Medical Genetics, 1 Moskvorechie St., Moscow, Russian Federation, 115478

Zinchenko R.A.

Research Center for Medical Genetics, 1 Moskvorech’e St., Moscow, Russian Federation, 115478;
Pirogov Russian National Research Medical University, 1 Ostrovityanova St., Moscow, Russian Federation, 117997

Savochkina O.A.

Research Institute of Eye Diseases, 11A Rossolimo St., Moscow, Russian Federation, 119021

Pupysheva A.D.

I.M. Sechenov First Moscow State Medical University, Department of Ophthalmology, 8-2 Trubetskaya St., Moscow, Russian Federation, 119991

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