The site of the Media Sphera Publishers contains materials intended solely for healthcare professionals.
By closing this message, you confirm that you are a certified medical professional or a student of a medical educational institution.

Bikbov M.M.

GBU "Ufimskiĭ NII glaznykh bolezneĭ" AN Respubliki Bashkortostan

Surkova V.K.

Ufa Eye Research Institute, Academy of Sciences of the Republic of Bashkortostan, 90 Pushkin St., Ufa, Russia, 450008

Prognostic value of changes in the cornea and conjunctiva in diabetes mellitus

Authors:

Bikbov M.M., Surkova V.K.

More about the authors

Journal: Russian Annals of Ophthalmology. 2019;135(1): 90‑97

Read: 3455 times


To cite this article:

Bikbov MM, Surkova VK. Prognostic value of changes in the cornea and conjunctiva in diabetes mellitus. Russian Annals of Ophthalmology. 2019;135(1):90‑97. (In Russ.)
https://doi.org/10.17116/oftalma201913501190

Recommended articles:
Main dire­ctions in corneal nerve fibers research. Russian Annals of Ophthalmology. 2024;(6):118-124
Diabetic reti­nopathy and pregnancy. Russian Annals of Ophthalmology. 2024;(6):145-151
Neurological complications resu­lting of nitrous oxide into­xication. S.S. Korsakov Journal of Neurology and Psychiatry. 2024;(12):41-46
Psoriasis: analysis of como­rbid pathology. Russian Journal of Clinical Dermatology and Vene­reology. 2025;(1):16-21
Cognitive functions asse­ssment of elde­rly patients with type 2 diabetes mellitus. S.S. Korsakov Journal of Neurology and Psychiatry. 2025;(3):46-50

References:

  1. Dedov II, Melnichenko GA. Endokrinologiya. Natsionalnoe rukovodstvo. M.: GEOTAR-Media; 2009. (In Russ.)
  2. Diabeticheskaya oftalmopatiya. Pod red. Balashevicha L.I., Izmaylova A.S. SPb.: Chelovek; 2012. (In Russ.)
  3. Dedov II. Diabetes mellitus: development of technologies in diagnostic, treatment and prevention. Saharnyiy diabet. 2010;3:6-10 (In Russ.)
  4. Avetisov SE, Chernenkova NA, Surnina ZV. Clinical features and diagnosis of diabetic polyneuropathy. Vestnik oftal’mologii. 2017;133(5):98-102. (In Russ.) https://doi.org/10.17116/oftalma2017133598-102
  5. Wild S, Roglic G, Greene A. Global prevalence of diabetes: estimates for the year 2000 and projections for 2030. Diabetes Care. 2004;27:1047-1053.
  6. Balashevich LI, Brzheskii VV, Izmailov AS i dr. Glaznyie proyaleniya diabeta. M.: Medicina; 2004. (In Russ.)
  7. Lockwood A, Hope-Ross M, Chell P. Neurotrophic keratopathy and diabetes mellitus. Eye (Lond). 2006;20:837-839.
  8. Sweeneya DF, Millarb TJ, Rajub SR. Tear film stability: A review. Exp Eye Res. 2013;117:28-38. https://doi.org/10.1016/j.exer.2013.08.010
  9. Safonova TN, Pateyuk LS. Ocular surface system. Vestnik oftal’mologii. 2015;131(1):96-102. (In Russ.) https://doi.org/10.17116/oftalma2015131196-102
  10. Marfurt CF, Cox J, Deek S, et al. Anatomy of the human corneal innervation. Exp. Eye Res. 2010;90:478-492. https://doi.org/10.1016/j.exer.2009.12.010
  11. Krasavina MI, Astahov SYu, Shadrichev FE, Dal NYu. Ophthalmic markers of the diabetic polyneuropathia. Oftalmologicheskie vedomosti. 2016;9(1):38-45. (In Russ.)
  12. Ylinen P, Laine I, Lindholm J-M, Tuuminen R. Poor glycemic control as a risk factor for pseudophakic cystoid macular edema in patients with diabetes. Journal of Cataract & Refractive Surgery. 2017;43(11):1376-1382.
  13. Demill DL, Hussain M, Pop-Busui R, Shtein RM. Ocular surface disease in patiets with diabetic peripheral neuropathy. Br Journal of Ophthalmol. 2015;307-369. https://doi.org/10.1136/bjophthalmol-2015-307369
  14. Somov EE. Klinicheskaya anatomiya organa zreniya. M. 2016. (In Russ.)
  15. Selitskaya TI, Pyankov VZ, Zapuskalov IV. Sosudyi kon’yunktivyi v norme i pri patologii. Tomsk. 1990. (In Russ.)
  16. Polunin GS, Polunina EG. Bolezni suhoy plenki ili bolezn «suhogo glaza»? Izbrannyie lektsii po oftalmologii. Pod red. Avetisova S.E. M.: Aprel; 2013. (In Russ.)
  17. Al-Aqaba MA, Fares U, Suleman H, et al. Architecture and distribution of human corneal nerves. Br J Ophthalmol. 2010;94:784-789. https://doi.org/10.1136/bjo.2009.173799
  18. Jiucheng He, Bazan NG, Bazan Haydee EP. Mapping the entire human corneal nerve architecture. Exp Eye Res. 2010;91:513-523. https://doi.org/10.1016/j.exer.2010.07.007
  19. Nitoda E, Kallinikos P, Pallikaris A, et al. Correlation of diabetic retinopathy and corneal neuropathy using confocal microscopy. Curr Eye Res. 2012;37(10):898-906. https://doi.org/10.3109/02713683.2012.683507
  20. Tavakoli M, Ferdousi M, Petropoulos IN, et al. Normative values for corneal nerve morphology assessed using corneal confocal microscopy: a multinational normative data set. Diabetes Care. 2015;38(5):838-843. https://doi.org/10.2337/dc14-2311
  21. Avetisov SE, Egorova GB, Kobzeva MV, et al. The clinical significance of contemporary research methods cornea. Vestnik oftal’mologii. 2013;5:22-31. (In Russ.)
  22. Rohlig M, Luboschik M, Kundt G, Stachs O, Peschel S, Zhivov A, Guthoff RF, Winter K, Schimann H. Visual analysis for an early detection of diabetic neuropathy. Klin Monbl Augenheilkd. 2014;231(12):1162-1169. https://doi.org/10.1055/s-0034-1383332
  23. Patel DV, McGhee CN. In vivo laser scanning confocal microscopy confirms that the human corneal sub-basal nerve plexus is a highly dynamic structure. Invest Ophthalmol Vis Sci. 2008;49:3409-3412. https://doi.org/10.1167/iovs.08-1951
  24. Petropoulos I, Manzoor T, Morgan P, et al. Repeatability of in vivo corneal confocal microscopy to quantify corneal nerve morphology. Cornea. 2012;32:83-89. https://doi.org/10.1097/ICO.0b013e3182749419
  25. Dabbah MA, Graham J, Petropoulos In, et al. Automatic analysis of diabetic peripheral neuropathy using multi-scale quantitative morphology of nerve fibres in corneal confocal microscopy imaging. Med image Anal. 2011;15:738-747. https://doi.org/10.1016/j.media.2011.05.016
  26. Egorova GB, Rogova AYa, Mitichkina TS. The diagnostic capabilities of confocal microscopy of primary corneal ectasia. Vestnik oftal’mologii. 2012;6:25-29. (In Russ.)
  27. Malik RA, Kallinikos P, Abbott CA, et al. Corneal confocal microscopy: a noninvasive surrogate of nerve fibre and repair in diabetic patients. Diabetologia. 2003;46:683-688.
  28. Lauria G, Hsieh ST, Johansson O, et al. European federation of neurological societies/peripheral Nerve Society Guideline on the use of skin biopsy in the diagnosis of small fiber neuropathy. Report of joint task forse of the European federation of neurological societies and the Peripheral Ner. Eur J Neurol. 2010;17:903-912. https://doi.org/10.1111/j.1468-1331.2010.03023.x
  29. Bikbova G, Oshitary T, Tawada A, Yamamoto S. Corneal changes in diabetes mellitus. Current Diabetes Reviews. 2012;8(4):294-302. https://doi.org/10.2174/157339912800840479
  30. Jabbert I, Stapleton F, Paras E, Sweeney DF. In vivo confocal microscopy of the human cornea. Br J Ophthalmol. 2003;87(2):225-236.
  31. Quattrini C, Tavakoli M, Jeziorska M, et al. Surrogate markers of small fiber damage in human diabetic neuropathy. Diabetes. 2007;56:2148-2154.
  32. Artemova EV, Galstyan GR, Atarshchikov DS, et al. Confocal microscopy of the cornea — a new non-invasive method of diagnostics of the initial manifestations of damage to the peripheral nervous system in diabetes mellitus. Problemy endrokrinologii. 2015;2:32-38. (In Russ.) https://doi.org/10.14341/probl201561232-38
  33. Shishko ON, Mohort TV, Konstantinova EE, Tsapaeva NL. Bulbar conjunctiva microcirculation changes in patients with carbohydrate metabolism disordersand obesity. Zdravoohranenie. 2015;2:4-9. (In Russ.)
  34. Solun MN, Kirichuk VF, Diht NI. Features of a microcirculator hemostasis at diabetes. Fundamentalnyie issledovaniya. 2008;6:67-69. (In Russ.)
  35. Rohlig M, Luboschik M, Kundt G, et al. Visual analysis for an early detection of diabetic neuropathy. Klin Monbl Augenheilkd. 2014;231(12):1162-1169. https://doi.org/10.1055/s-0034-1383332
  36. Bikbov MM, Surkova VK. Cornea and its changes in diabetes mellitus. Saharnyiy diabet. 2016;19(6):479-485. (In Russ.)
  37. Inoue K, Kato S, Ohara C, Numaga J, Amano S, Oshika T. Ocular and systemic factors relevant to diabetic keratoepitheliopathy. Cornea. 2001;20(8):798-801.
  38. Saldanha IJ, Dickersin K, Hutfless ST, Akpek EK. Gaps in Current Knowledqe and Priorities for Future Research in Dry Eye. Cornea. 2017;36(12):1486-1491.
  39. Brzheskij VV. Rogovichno-konjunktival’nyj kseroz (diagnostika, klinika, lechenie). SPb.: Saga; 2002. (In Russ.)
  40. Kallinikos P, Berhanu M, O’Donnell C, et al. Corneal nerve tortuosity in diabetic patients with neuropathy. Invest Ophthalmol Vis Sci. 2004;45:418-422.
  41. Ioannis N, Petropoulos Msc, Tauseef Monzoor, et al. Repeatability of in vivo corneal confocal microsopy to quantify corneal nerve morplology. Cornea. 2013;32:82-89. https://doi.org/10.1097/ICO.0b013e3182749419
  42. Dehghani C, Pritchard N, Edwards K, et al. Fully automated, semiautomated, and manual morphometric analysis of corneal subbasal nerve plexus in individuals with and without diabetes. Cornea. 2014;33:696-702. https://doi.org/10.1097/ICO.0000000000000152
  43. Surnina ZV. Features a light and laser biomicroscopy of the cornea in the early diagnosis of diabetic polyneuropathy. Vestnik oftal’mologii. 2015;131(1):104-108. (In Russ.) https://doi.org/10.17116/oftalma20151311104-108
  44. Avetisov SE, Novikov IA, Mahotin SS, Surnina ZV. The new principle of morphometric studies of corneal nerve fibers based on confocal biomicroscopy diabetes. Vestnik oftal’mologii. 2015;131(4):5-14. (In Russ.) https://doi.org/10.17116/oftalma201513145-14
  45. Edwards K, Pritchard N, Vagenas D, et al. Short Report: complications standardizing corneal nerve fibre length for nerve tortuosity increases its association with measures of diabetic neuropathy. Diabetic medicine. 2014;31(10):1205-1209. https://doi.org/10.1111/dme.12466
  46. Quadrado M, Popper M, Morgado A, et al. Diabetes and corneal cell density in humans by in vivo confocal microscopy. Cornea. 2006;25:761-768.
  47. Efron N, Lee G, Lim RN, et al. Development and validation of the QUT Corneal Nerve Grading Scale. Cornea. 2014;33:376-381. https://doi.org/10.1097/ICO.0000000000000084
  48. Shenoy R, Khadekar R, Bialasiewicz A, Muniri A. Corneal endothelium in patients with diabetes mellitus: a historical cohort study. Eur J Ophthalmol. 2009;19:369-375.
  49. Leelawongtawun W, Suphachearaphan W, Kampitak K, Leelawongtawun R. A comparative study of corneal endothelial structure between diabetes and non-diabetes. J Med Assos Thai. 2015;98(5):484-488.
  50. Avetisov CE, Novikov IA, Makhotin SS, Surnina ZV. Calculation of Anisotropy and Symmetry Coefficients of Corneal Nerve Orientation Based on Automated Recognition of Digital Confocal Images. Meditcinskaya tehnika. 2015;49(3):23-25. (In Russ.) https://doi.org/10.1007/s10527-015-9519-5
  51. Bikbov MM, Surkova VK, Zainullina NB, Gumerova SG. Morphological changes in cornea after corneal collagen cross-linking as keratoconus treatment. Kataraktalnaya i refraktsionnaya hirurgiya. 2014;14(3):18-22. (In Russ.)
  52. Goldich Y, Barkana Y, Gerber Y. et al. Effect of diabetes mellitus on biomechanical parameters of the cornea. J Cataract Refract Surg. 2009;35:715-719.
  53. Bikbov MM, Bikbova GM. Ehktazii rogovicy. M.: Oftal’mologija. 2011. (In Russ.)
  54. Naderan M, Naderan M, Rezagholizadeh F, et al. Association between diabetes and keratoconus: a case-control study. Cornea. 2014;33:1271-1273. https://doi.org/10.1097/ICO.0000000000000282
  55. Kuo IC, Broman A, Pirouzmanesh A, et al. Is there an association between diabetes and keratoconus? Ophthalmology. 2006;113:184-190.
  56. Malyugin BE, Martsinkevich AO. Modern approaches to the prevention of post-cataract surgery inflammation in diabetic patients. Oftal’mohirurgija. 2016;1:85-90. (In Russ.)
  57. Kopaev SYu, Pyitskaya NV, Kopaeva VG, Menshikov AYu. Cataract surgery at diabetes. Prakticheskaya meditsina. 2017;9:103-106. (In Russ.)

Email Confirmation

An email was sent to test@gmail.com with a confirmation link. Follow the link from the letter to complete the registration on the site.

Email Confirmation

We use cооkies to improve the performance of the site. By staying on our site, you agree to the terms of use of cооkies. To view our Privacy and Cookie Policy, please. click here.