The site of the Media Sphera Publishers contains materials intended solely for healthcare professionals.
By closing this message, you confirm that you are a certified medical professional or a student of a medical educational institution.

Login
EN
Phones:
+7 (495) 482-4118
+7 (495) 482-4329
  • Toll-free number for subscriptions:
    +8 800 250-18-12
    Mon-Fri from 10 a.m. to 6 p.m.

  • © 1998-2026
+7 (495) 482-43-29
EN
All journals
Journal
Year
Year
Search result: 0

Erichev V.P.

FGBU "Nauchno-issledovatel'skiĭ institut glaznykh bolezneĭ" RAMN, Moskva

Panyushkina L.A.

Research Institute of Eye Diseases, 11 A, B Rossolimo St., Moscow, Russian Federation, 119021

Ronzina I.A.

FGBU "NII glaznykh bolezneĭ" RAMN, Moskva

Dissociation of structural and functional parameters of the retina and optic nerve in a patient with Alzheimer`s disease (clinical case)

Authors:

Erichev V.P., Panyushkina L.A., Ronzina I.A.

More about the authors

Journal: Russian Annals of Ophthalmology. 2015;131(2): 89‑93

DOI: 10.17116/oftalma2015131289-93

Read: 1293 times

Contact the author
Table of contents

DISSOCIATION OF STRUCTURAL AND FUNCTIONAL PARAMETERS OF THE RETINA AND OPTIC NERVE IN A PATIENT WITH ALZHEIMER`S DISEASE (CLINICAL CASE)
DISSOCIATION OF STRUCTURAL AND FUNCTIONAL PARAMETERS OF THE RETINA AND OPTIC NERVE IN A PATIENT WITH ALZHEIMER`S DISEASE (CLINICAL CASE)

To cite this article:

Erichev VP, Panyushkina LA, Ronzina IA. Dissociation of structural and functional parameters of the retina and optic nerve in a patient with Alzheimer`s disease (clinical case). Russian Annals of Ophthalmology. 2015;131(2):89‑93. (In Russ.)
https://doi.org/10.17116/oftalma2015131289-93

Подписка 2026 Вестник офтальмологии (Russian Annals of Ophthalmology)
МСФ на ЯМ
Использование инфографики авторами научных работ
Close metadata
Recommended articles:
Nano­second reti­nal laser therapy: three years of practical expe­rience. Russian Annals of Ophthalmology. 2025;(4):60-65
Mole­cular diagnostic biomarkers of subretinal fluid in asse­ssing the seve­rity and prognosis of rhegmatogenous reti­nal deta­chment. Russian Annals of Ophthalmology. 2025;(6):119-126
Features of facial expressions in patients with cognitive impairment due to Alzheimer’s disease. S.S. Korsakov Journal of Neurology and Psychiatry. 2025;(7):104-109
Diagnosis of Alzheimer’s disease using biological markers in corticobasal syndrome. S.S. Korsakov Journal of Neurology and Psychiatry. 2025;(8):133-139
Amyloidogenesis and neurotrophic dysfunction in age-related macu­lar dege­neration in correlation with Alzheimer’s disease. Russian Journal of Archive of Pathology. 2025;(6):61-68
Age-related pathomorphological changes in the brain of non-human primates. Mole­cular Gene­tics, Microbiology and Viro­logy. 2025;(4-2):143-149
Epileptic seizures in patients with Alzheimer’s disease. S.S. Korsakov Journal of Neurology and Psychiatry. 2025;(11):36-43
A new look at blood biomarkers in Alzheimer’s patients. S.S. Korsakov Journal of Neurology and Psychiatry. 2025;(12):7-13
Neurogenesis in neurodegeneration: multifactorial regu­lation, mechanisms of impairment, and therapeutic stra­tegies. S.S. Korsakov Journal of Neurology and Psychiatry. 2025;(12):14-21
Combination of amyotrophic late­ral scle­rosis with Alzheimer’s disease. S.S. Korsakov Journal of Neurology and Psychiatry. 2026;(1):132-136
Abstract:

Visual impairment is often one of the earliest sings of Alzheimer’s disease. This article reports a clinical case of a female patient diagnosed with mild dementia due to Alzheimer’s disease. As revealed by a comprehensive examination, her visual fields and visual evoked potentials were markedly changed, while morphometric parameters of the retina and optic nerve appeared normal. Such a significant dissociation of structural and functional parameters may indicate a more proximal involvement of visual pathways in Alzheimer’s disease.

Keywords:

Alzheimer’s disease
visual impairment
optical coherence tomography
visual evoked potentials

Authors:

Erichev V.P.

FGBU "Nauchno-issledovatel'skiĭ institut glaznykh bolezneĭ" RAMN, Moskva

Panyushkina L.A.

Research Institute of Eye Diseases, 11 A, B Rossolimo St., Moscow, Russian Federation, 119021

Ronzina I.A.

FGBU "NII glaznykh bolezneĭ" RAMN, Moskva

Close metadata

References:

  1. Gavrilova S. Bolezn' Al'tsgeimera (dementsiya al'tsgeimerovskogo tipa). V kn.: Neirodegenerativnye bolezni i starenie. Ruk-vo dlya vrachei. Pod red. Zavalishina I, Yakhno N, Gavrilovoi S. M.; 2001:9-79. (In Russ.)
  2. Albert MS, DeKosky ST, Dickson D, Dubois B, Feldman HH, Fox NC, Gamst A, Holtzman D, Jagust W, Petersen R, Snyder P, Carrillo M, Thies B, Phelps C. The diagnosis of mild cognitive impairment due to Alzheimer’s disease: recommendations from the National Institute on Aging-Alzheimer’s Association workgroups on diagnostic guidelines for Alzheimer’s disease. Alzheimer's & Dementia. 2011;7(3):270-279. doi:10.1016/j.jalz.2011.03.008
  3. Pache M, Smeets CH, Gasio P, Savaskan E, Flammer J, Wirz-Justice A, Kaiser HJ. Colour vision deficiencies in Alzheimer’s disease. Age Ageing. 2003;32(4):422-426. doi:10.1093/ageing/32.4.422
  4. Parisi V, Restuccia R, Fattapposta F, Mina C, Bucci MG, Pierelli F. Morphological and functional retinal impairment in Alzheimer’s disease patients. Clin Neurophysiol. 2001;112(10):1860-1867. doi:10.1016/s1388-2457(01)00620-4
  5. Berisha F, Feke GT, Trempe CL, McMeel JW, Schepens CL. Retinal abnormalities in early Alzheimer’s disease. Investigative Ophthalmology & Visual Science. 2007;48(5):2285-2289. doi:10.1167/iovs.06-1029
  6. Iseri PK, Altinas O, Tokay T, Yuksel N. Relationship between cognitive impairment and retinal morphological and visual functional abnormalities in Alzheimer’s disease. Journal of Neuro-Ophthalmology. 2006;26(1):18-24. doi:10.1097/01.wno.0000204645.56873.26
  7. Trick GL, Trick LR, Morris P, Wolf M. Visual field loss in senile dementia of the Alzheimer’s disease type. Neurology. 1995;45(1):68-74. doi:10.1212/wnl.45.1.68
  8. Erichev V, Panyushkina L. The diagnostic value of functional and morphometric parameters of the retina and optic nerve in patients with Alzheimer’s disease. Nacional'nyj zhurnal glaucoma. 2014;2:5-10. (In Russ.)
  9. Armstrong RA. Visual field defects in Alzheimer’s disease patients may reflect differential pathology in the primary visual cortex. Optometry and Vision Science. 1996;73(11):677-682. doi:10.1097/00006324-199611000-00001
  10. Hof PR, Morrison JH. Quantitative analysis of a vulnerable subset of pyramidal neurons in Alzheimer’s disease: II. Primary and secondary visual cortex. J Comp Neurol. 1990;301(1):55-64. doi:10.1002/cne.903010106
  11. Lewis DA, Campbell MJ, Terry RD, Morrison JH. Laminar and regional distributions of neurofibrillary tangles and neuritic plaques in Alzheimer’s disease: a quantitative study of visual and auditory cortices. J Neurosci. 1987;7(6):1799-1808.
  12. Erichev V, Tumanov V, Panyushkina L, Fedorov A. Comperative analysis of morphological changes in the optic centers in patients with glaucoma and Alzheimer’s disease. Nacional'nyj zhurnal glaucoma. 2014;3:5-13. (In Russ.)
Contact the author
Email
Message
The publishing house "Media Sphere" does not provide treatment services, does not give recommendations on contacting medical institutions and specific specialists, on the prescription of medicines and dietary supplements.

Email Confirmation

An email was sent to test@gmail.com with a confirmation link. Follow the link from the letter to complete the registration on the site.

Email Confirmation

Contact us
If you have any questions, complaints or suggestions, please use this feedback form.
Email
Message
The publishing house "Media Sphere" does not provide treatment services, does not give recommendations on contacting medical institutions and specific specialists, on the prescription of medicines and dietary supplements.
Submit Application

You can become an author of one of our magazines, send a request and we will consider it in during the day.

Name
Phone
E-mail
Message
Login
Registration
E-mail
Password
Forgot Password?

Log in to the site using your account in one of the services

Password recovery
E-mail
Login
Register

We use cооkies to improve the performance of the site. By staying on our site, you agree to the terms of use of cооkies. To view our Privacy and Cookie Policy, please. click here.