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Grigorian O.R.

FGU Éndokrinologicheskiĭ nauchnyĭ tsentr Minzdravsotsrazvitiia Rossii, Moskva

Volevodz N.N.

Éndokrinologicheskiĭ nauchnyĭ tsentr, Moskva

Andreeva E.N.

Mediko-geneticheskoe otdelenie Moskovskogo oblastnogo NII akusherstva i ginekologii

Pregravid preparation of diabetic women

Authors:

Grigorian O.R., Volevodz N.N., Andreeva E.N.

More about the authors

Journal: Therapeutic Archive. 2016;88(7): 114‑119

DOI: 10.17116/terarkh2016887114-119

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Table of contents

PREGRAVID PREPARATION OF DIABETIC WOMEN
PREGRAVID PREPARATION OF DIABETIC WOMEN

To cite this article:

Grigorian OR, Volevodz NN, Andreeva EN. Pregravid preparation of diabetic women. Therapeutic Archive. 2016;88(7):114‑119. (In Russ.)
https://doi.org/10.17116/terarkh2016887114-119

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Abstract:

Pregnancy in women with type 1 or 2 diabetes mellitus (DM) is associated with an increased risk for complications in both the mother and her fetus. The impact of these complications on modifiable risk factors may substantially improve pregnancy outcomes and reduce malformation rates in children. This is a goal of pregravid preparation (PGP) in this category of patients. The review gives the main points of PGP in patients with types 1 and DM and shows the results of main studies providing evidence for PGP in DM. In particular, by the moment of conception, DM patients should achieve a glycosylated hemoglobin (HbA1c) goal of <6% no later than 4 weeks before conception and during the first trimester of pregnancy, take folic acid in a high dose (at least 4000 µg, or 4 mg, daily), quit tobacco smoking and alcohol use, receive potentially teratogenic drugs, and, if need be, lose weight (the target body mass index of <27 kg/m2).

Keywords:

diabetes mellitus
pregravid preparation
preconception preparation
folic acid
folacin

Authors:

Grigorian O.R.

FGU Éndokrinologicheskiĭ nauchnyĭ tsentr Minzdravsotsrazvitiia Rossii, Moskva

Volevodz N.N.

Éndokrinologicheskiĭ nauchnyĭ tsentr, Moskva

Andreeva E.N.

Mediko-geneticheskoe otdelenie Moskovskogo oblastnogo NII akusherstva i ginekologii

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References:

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