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Tuter D.S.

I.M. Sechenov First Moscow State Medical University, Moscow, Russia

Kopylov F.Iu.

Pervyĭ MGMU im. I.M. Sechenova, kafedra profilakticheskoĭ i neotlozhnoĭ kardiologii FPPOV, Moskva

Kozlovskaya N.L.

Department of Nephrology and Hemodialysis, I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia;
Research Department of Nephrology, Research Center, I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia, Moscow, Russia

Dem'ianova K.A.

Kafedra nefrologii i gemodializa instituta professional'nogo obrazovaniia GBOU VPO "Pervyĭ MGMU im. I.M. Sechenova" Minzdrava Rossii

Shchekochikhin D.Iu.

Pervyĭ Moskovskiĭ gosudarstvennyĭ meditsinskiĭ universitet im. I.M. Sechenova;
Moskovskiĭ gosudarstvennyĭ universitet im. M.V. Lomonosova

Shilov E.M.

Kafedra nefrologii

Syrkin A.L.

Sechenov First Moscow State Medical University

Cardiac involvement in thrombotic microangiopathies

Authors:

Tuter D.S., Kopylov F.Iu., Kozlovskaya N.L., Dem'ianova K.A., Shchekochikhin D.Iu., Shilov E.M., Syrkin A.L.

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Journal: Therapeutic Archive. 2015;87(9): 17‑25

DOI: 10.17116/terarkh201587917-25

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Table of contents

CARDIAC INVOLVEMENT IN THROMBOTIC MICROANGIOPATHIES
CARDIAC INVOLVEMENT IN THROMBOTIC MICROANGIOPATHIES

To cite this article:

Tuter DS, Kopylov FIu, Kozlovskaya NL, Dem'ianova KA, Shchekochikhin DIu, Shilov EM, Syrkin AL. Cardiac involvement in thrombotic microangiopathies. Therapeutic Archive. 2015;87(9):17‑25. (In Russ.)
https://doi.org/10.17116/terarkh201587917-25

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Aim. To describe cardiac involvement in patients with acute thrombotic microangiopathy (TMA). Materials and methods. The case histories of 46 patients with proven TMA, including 17 patients diagnosed with atypical hemolytic uremic syndrome (aHUS) and 29 patients with catastrophic antiphospholipid syndrome (CAPS), were analyzed. Results. Different documentarily verified signs of cardiac involvement were revealed in 6 (13%) patients (5 and 1 patients diagnosed as having aHUS and CAPS, respectively). Five patients developed myocardial involvement at disease onset in the presence of multiple organ dysfunction. Conclusion. Cases of cardiac involvement in TMA of various genesis are presented. The exact incidence of myocardial involvement and its prognostic value are unknown so far.

Keywords:

thrombotic microangiopathies
atypical hemolytic uremic syndrome
catastrophic antiphospholipid syndrome
noncoronarogenic myocardial infarction
heart failure

Authors:

Tuter D.S.

I.M. Sechenov First Moscow State Medical University, Moscow, Russia

Kopylov F.Iu.

Pervyĭ MGMU im. I.M. Sechenova, kafedra profilakticheskoĭ i neotlozhnoĭ kardiologii FPPOV, Moskva

Kozlovskaya N.L.

Department of Nephrology and Hemodialysis, I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia;
Research Department of Nephrology, Research Center, I.M. Sechenov First Moscow State Medical University, Ministry of Health of Russia, Moscow, Russia

Dem'ianova K.A.

Kafedra nefrologii i gemodializa instituta professional'nogo obrazovaniia GBOU VPO "Pervyĭ MGMU im. I.M. Sechenova" Minzdrava Rossii

Shchekochikhin D.Iu.

Pervyĭ Moskovskiĭ gosudarstvennyĭ meditsinskiĭ universitet im. I.M. Sechenova;
Moskovskiĭ gosudarstvennyĭ universitet im. M.V. Lomonosova

Shilov E.M.

Kafedra nefrologii

Syrkin A.L.

Sechenov First Moscow State Medical University

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