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Chikh E.V.

Kafedra klinicheskoĭ farmakologii i propedevtiki vnutrennikh bolezneĭ GBOU VPO "Pervyĭ Moskovskiĭ gosudarstvennyĭ meditsinskiĭ universitet im. I.M. Sechenova"

Makhova A.A.

Sechenov First Moscow State Medical University, Moscow, Russia

Role of ascorbic acid and tocopherol in the prevention and treatment of diseases from the standpoint of evidence-based medicine

Authors:

Chikh E.V., Makhova A.A.

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Journal: Therapeutic Archive. 2015;87(4): 98‑102

DOI: 10.17116/terarkh201587498-102

Read: 24146 times

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ROLE OF ASCORBIC ACID AND TOCOPHEROL IN THE PREVENTION AND TREATMENT OF DISEASES FROM THE STANDPOINT OF EVIDENCE-BASED MEDICINE
ROLE OF ASCORBIC ACID AND TOCOPHEROL IN THE PREVENTION AND TREATMENT OF DISEASES FROM THE STANDPOINT OF EVIDENCE-BASED MEDICINE

To cite this article:

Chikh EV, Makhova AA. Role of ascorbic acid and tocopherol in the prevention and treatment of diseases from the standpoint of evidence-based medicine. Therapeutic Archive. 2015;87(4):98‑102. (In Russ.)
https://doi.org/10.17116/terarkh201587498-102

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Abstract:

The role of vitamin C and vitamin E in the prevention and treatment of diseases is analyzed from the standpoint of evidence-based medicine. The high provision of a patient with the vitamins has a therapeutic and preventive impact on the development and course of a number of diseases. Furthermore, when additionally prescribing the vitamins as part of combination therapy, it is necessary to take into account possible drug interactions, including those due to the inducing effect of the above antioxidants on cytochrome P450 3A4.

Keywords:

vitamin C
vitamin E
antioxidants
cytochromes P450
cardiovascular diseases
diabetes mellitus
stroke
induction of metabolic enzymes

Authors:

Chikh E.V.

Kafedra klinicheskoĭ farmakologii i propedevtiki vnutrennikh bolezneĭ GBOU VPO "Pervyĭ Moskovskiĭ gosudarstvennyĭ meditsinskiĭ universitet im. I.M. Sechenova"

Makhova A.A.

Sechenov First Moscow State Medical University, Moscow, Russia

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