The site of the Media Sphera Publishers contains materials intended solely for healthcare professionals.
By closing this message, you confirm that you are a certified medical professional or a student of a medical educational institution.

Login
EN
+7 (495) 482-4118
+7 (495) 482-0604
+8 800 250-18-12
  • (toll-free number for subscriptions)
    Mon-Fri from 10 a.m. to 6 p.m.

  • © 1998-2025
+7 (495) 482-43-29
EN
All journals
Journal
Year
Year
Search result: 0

Dedov I.I.

Endocrinology Research Centre

Shestakova M.V.

Institut diabeta Éndokrinologicheskogo nauchnogo tsentra, Moskva

The metabolic memory phenomenon in predicting a risk for vascular complications in diabetes mellitus

Authors:

Dedov I.I., Shestakova M.V.

More about the authors

Journal: Therapeutic Archive. 2015;87(10): 4‑10

DOI: 10.17116/terarkh201587104-10

Read: 5817 times

Download PDF (RU)
Contact the author
Table of contents

THE METABOLIC MEMORY PHENOMENON IN PREDICTING A RISK FOR VASCULAR COMPLICATIONS IN DIABETES MELLITUS
THE METABOLIC MEMORY PHENOMENON IN PREDICTING A RISK FOR VASCULAR COMPLICATIONS IN DIABETES MELLITUS

To cite this article:

Dedov II, Shestakova MV. The metabolic memory phenomenon in predicting a risk for vascular complications in diabetes mellitus. Therapeutic Archive. 2015;87(10):4‑10. (In Russ.)
https://doi.org/10.17116/terarkh201587104-10

МСФ на ЯМ
Использование инфографики авторами научных работ
Close metadata
Recommended articles:
Oxidative stress in the pathogenesis of chro­nic headache. S.S. Korsakov Journal of Neurology and Psychiatry. 2024;(10):35-40
Alte­rations in the acti­vity of glutathione-dependent enzy­mes in erythrocytes of patients with acute pancreatitis of varying seve­rity. Russian Journal of Evidence-Based Gastroenterology. 2024;(4):10-15
The role of quantitative body composition analysis in popu­lation in the asse­ssment and moni­toring of cardiovascular risk meta­bolic factors. Russian Journal of Preventive Medi­cine. 2024;(12):128-134
Epigenetic regu­lation in the placenta in case of impaired trophoblast inva­sion (a review). Russian Journal of Human Reproduction. 2024;(6):45-54
Restoration of spermatogenesis suppressed by the use of testosterone, antiestrogen therapy in men with type 2 diabetes mellitus. Russian Journal of Human Reproduction. 2024;(6):156-160
Diabetic reti­nopathy and pregnancy. Russian Annals of Ophthalmology. 2024;(6):145-151
Oxidative stress and antioxidant protection in diso­rders of cere­bral circulation. S.S. Korsakov Journal of Neurology and Psychiatry. 2024;(12):114-119
Arte­rial hype­rtension is an oxidative stress, as a pathogenetic target for the treatment of chro­nic cere­brovascular insu­fficiency. S.S. Korsakov Journal of Neurology and Psychiatry. 2025;(1):84-90
Psoriasis: analysis of como­rbid pathology. Russian Journal of Clinical Dermatology and Vene­reology. 2025;(1):16-21
Cognitive functions asse­ssment of elde­rly patients with type 2 diabetes mellitus. S.S. Korsakov Journal of Neurology and Psychiatry. 2025;(3):46-50
Abstract:

The paper presents data on positive and negative metabolic memory phenomena in patients with type 1 and type 2 diabetes mellitus (DM) as exemplified by the long-term randomized trials DCCT, UKPDS, ACCORD, VADT, and ADVANCE. It discusses the role of metabolic memory in predicting a risk for vascular complications in DM. Ideas on the mechanisms of this phenomenon, which are based on the activation of oxidative stress, the production of irreversible glycation products, and epigenetic disorders, are given.

Keywords:

diabetes mellitus
positive and negative metabolic memory
micro- and macroangiopathies
oxidative stress
epigenetics

Authors:

Dedov I.I.

Endocrinology Research Centre

Shestakova M.V.

Institut diabeta Éndokrinologicheskogo nauchnogo tsentra, Moskva

Close metadata

Contact the author
Email
Message
The publishing house "Media Sphere" does not provide treatment services, does not give recommendations on contacting medical institutions and specific specialists, on the prescription of medicines and dietary supplements.

Email Confirmation

An email was sent to test@gmail.com with a confirmation link. Follow the link from the letter to complete the registration on the site.

Email Confirmation

Contact us
If you have any questions, complaints or suggestions, please use this feedback form.
Email
Message
The publishing house "Media Sphere" does not provide treatment services, does not give recommendations on contacting medical institutions and specific specialists, on the prescription of medicines and dietary supplements.
Submit Application

You can become an author of one of our magazines, send a request and we will consider it in during the day.

Name
Phone
E-mail
Message
Login
Registration
E-mail
Password
Forgot Password?

Log in to the site using your account in one of the services

Password recovery
E-mail
Login
Register

We use cооkies to improve the performance of the site. By staying on our site, you agree to the terms of use of cооkies. To view our Privacy and Cookie Policy, please. click here.