Estimation of central blood pressure and arterial stiffness in pregnant women with different forms of hypertension

Chulkov V.S.; Vereina N.K.; Sinitsyn S.P.; Dolgushina V.F.

doi:https://doi.org/10.17116/terarkh2014861215-19

Chulkov V.S.

Kafedra vnutrennikh bolezneĭ i éndokrinologii Cheliabinskoĭ gosudarstvennoĭ meditsinskoĭ akademii

ORCID: 0000-0002-0952-6856

Vereina N.K.

Kafedra vnutrennikh bolezneĭ i éndokrinologii Cheliabinskoĭ gosudarstvennoĭ meditsinskoĭ akademii

Sinitsyn S.P.

Kafedra vnutrennikh bolezneĭ i éndokrinologii Cheliabinskoĭ gosudarstvennoĭ meditsinskoĭ akademii

Dolgushina V.F.

Kafedra akusherstva i ginekologii

ORCID: 0000-0002-3929-7708

Estimation of central blood pressure and arterial stiffness in pregnant women with different forms of hypertension

Authors:

Chulkov V.S., Vereina N.K., Sinitsyn S.P., Dolgushina V.F.

More about the authors

Journal: Therapeutic Archive. 2014;86(12): 15‑19

DOI: 10.17116/terarkh2014861215-19

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To cite this article:

Chulkov VS, Vereina NK, Sinitsyn SP, Dolgushina VF. Estimation of central blood pressure and arterial stiffness in pregnant women with different forms of hypertension. Therapeutic Archive. 2014;86(12):15‑19. (In Russ.)
https://doi.org/10.17116/terarkh2014861215-19

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Abstract:

Aim. To estimate central (aortic) blood pressure (BP) and arterial stiffness and their prognostic value in the development of preeclampsia (PE) in pregnant women with different forms of hypertension. Subjects and methods. The study included 106 patients with chronic hypertension, 21 with the latter concurrent with PE, 63 with gestational hypertension, 10 with PE, and 100 without hypertension. All the women underwent 24-hour BP monitoring by an oscillometric method to estimate central (aortic) BP and arterial stiffness at 16-22 weeks' gestation. Results. The highest average daily central systolic and diastolic BP was in the pregnant women with PE. ROC analysis showed that the average daily aortic systolic BP greater than 115 mm Hg was most significant for the prediction of PE. The highest values of arterial stiffness (augmentation index, stiffness, maximum rate of blood pressure rise) were detected in the pregnant women with PE in the presence of chronic hypertension. Conclusion. 24-four BP monitoring in pregnant women can provide additional characteristics that reflect the stiffness of the aorta and peripheral arteries, which may be used to predict PE.

Keywords:

hypertension

pregnancy

central (aortic) blood pressure

arterial stiffness

Authors:

Chulkov V.S.

Kafedra vnutrennikh bolezneĭ i éndokrinologii Cheliabinskoĭ gosudarstvennoĭ meditsinskoĭ akademii

ORCID: 0000-0002-0952-6856

Vereina N.K.

Kafedra vnutrennikh bolezneĭ i éndokrinologii Cheliabinskoĭ gosudarstvennoĭ meditsinskoĭ akademii

Sinitsyn S.P.

Kafedra vnutrennikh bolezneĭ i éndokrinologii Cheliabinskoĭ gosudarstvennoĭ meditsinskoĭ akademii

Dolgushina V.F.

Kafedra akusherstva i ginekologii

ORCID: 0000-0002-3929-7708

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