The paper gives the current aspects of the etiology and pathogenesis of acute tonsillopharyngitis and its complications. Correct evaluation of the clinical manifestations of the disease is noted to be of importance in choosing adequate treatment policy and preventing unfavorable trends in the development of the disease. Antibacterial therapy for streptococcal tonsillopharyngitis is emphasized to be of significance. The paper shows that it is expedient to perform irrigation procedures (different types of rinsing) that ensure a significant contact area and optimal conditions for the better local effect of antibacterial solutions, in particular furasol, a nitrofuran derivative (the active ingredient is furasidine potassium; the excipient is sodium chloride). There are clinical findings suggesting that furasol has a positive effect on the intensity and duration of oropharyngeal inflammatory changes, suggesting that it is advisable to use it in respective clinical situations.