The site of the Media Sphera Publishers contains materials intended solely for healthcare professionals.
By closing this message, you confirm that you are a certified medical professional or a student of a medical educational institution.

Login
EN
+7 (495) 482-4118
+7 (495) 482-0604
+8 800 250-18-12
  • (toll-free number for subscriptions)
    Mon-Fri from 10 a.m. to 6 p.m.

  • © 1998-2025
+7 (495) 482-43-29
EN
All journals
Journal
Year
Year
Search result: 0

Timoshevskiĭ A.A.

Pervyĭ Moskovskiĭ gosudarstvennyĭ meditsinskiĭ universitet im. I.M. Sechenova

Pigolkin Yu.I.

Sechenov’s First Moscow State Medical University, Moscow, Russia

Grebeniuk A.N.

Voenno-meditsinskaia akademiia im. S.M. Kirova, Sankt-Peterburg

The use of immunological characteristics of the peripheral blood for the purpose of forensic medical expertise of the subjects exposed to ionizing radiation

Authors:

Timoshevskiĭ A.A., Pigolkin Yu.I., Grebeniuk A.N.

More about the authors

Journal: Forensic Medical Expertise. 2013;56(1): 17‑20

Views: 807

Downloaded: 9

Download PDF (RU)
Contact the author
Table of contents

THE USE OF IMMUNOLOGICAL CHARACTERISTICS OF THE PERIPHERAL BLOOD FOR THE PURPOSE OF FORENSIC MEDICAL EXPERTISE OF THE SUBJECTS EXPOSED TO IONIZING RADIATION
THE USE OF IMMUNOLOGICAL CHARACTERISTICS OF THE PERIPHERAL BLOOD FOR THE PURPOSE OF FORENSIC MEDICAL EXPERTISE OF THE SUBJECTS EXPOSED TO IONIZING RADIATION

To cite this article:

Timoshevskiĭ AA, Pigolkin YuI, Grebeniuk AN. The use of immunological characteristics of the peripheral blood for the purpose of forensic medical expertise of the subjects exposed to ionizing radiation. Forensic Medical Expertise. 2013;56(1):17‑20. (In Russ.)

Подписка 2025-2 (Forensic Medical Expertise)
 
МСФ на ЯМ
Close metadata
Recommended articles:
Legal and fore­nsic medi­cal problems of postmortem dona­tion. Fore­nsic Medi­cal Expe­rtise. 2024;(3):5-9
Causal links in fore­nsic medi­cine in cases of acute ente­ric infe­ctions. Fore­nsic Medi­cal Expe­rtise. 2024;(3):19-23
Diagnostic criteria of death cause from low temperature in air and water esta­blished by traditional expert examination methods. Fore­nsic Medi­cal Expe­rtise. 2024;(3):29-33
Is this iatrogenic pathology or rare disease?. Fore­nsic Medi­cal Expe­rtise. 2024;(3):45-49
Fore­nsic characteristic of drowning cases in the Russian Fede­ration for the period from 2013 to 2022. Fore­nsic Medi­cal Expe­rtise. 2024;(4):11-15
Inno­vations in fore­nsic medi­cine: accu­racy, evidence and effe­ctiveness of expe­rtises in emergencies in case of mass fata­lity. Fore­nsic Medi­cal Expe­rtise. 2024;(4):22-26
Analysis of defe­cts in health care deli­very for children based on the data of commission fore­nsic medi­cal examinations performed in the Repu­blic of Uzbe­kistan. Fore­nsic Medi­cal Expe­rtise. 2024;(5):15-18
On improvement of legal regu­lation of personnel training in the sphere of state fore­nsic medi­cal acti­vity. Fore­nsic Medi­cal Expe­rtise. 2024;(5):62-66
Study of the effe­ctiveness of different methods of exte­rnal psoriasis therapy in a new expe­rimental model of chro­nic inflammation. Russian Journal of Clinical Dermatology and Vene­reology. 2024;(5):552-557
Legal regu­lation of fore­nsic medi­cal examinations in 2024 and nece­ssary data for anesthesiologists invo­lved in these procedures. Russian Journal of Anesthesiology and Reanimatology. 2024;(6):104-109

The objective of the present study was the comprehensive evaluation of quantitative and functional metabolic characteristics of human leukocytes following in vitro irradiation of peripheral blood samples at a dose of 0.25, 0.50, 1.0, and 4.0 Gy for the development of a rationale for their application as biological markers of radiation exposure in forensic medical expertise of the subjects affected by supernormal ionizing radiation. The total number of leukocytes, lymphocytes, and their subpopulations as well as the functional and metabolic status of neutrophils were determined. The results of the study indicate the possibility of using a set of functional metabolic characteristics of human leukocytes as the additional forensic medical criteria for diagnostics of radiation impact on living subjects.

Keywords:

forensic medical expertise
neutrophils
lymphocytes
in vitro irradiation
forensic medical expertise
neutrophils
lymphocytes
in vitro irradiation

Authors:

Timoshevskiĭ A.A.

Pervyĭ Moskovskiĭ gosudarstvennyĭ meditsinskiĭ universitet im. I.M. Sechenova

Pigolkin Yu.I.

Sechenov’s First Moscow State Medical University, Moscow, Russia

Grebeniuk A.N.

Voenno-meditsinskaia akademiia im. S.M. Kirova, Sankt-Peterburg

List of references:

  1. Avetisov G.M., Goncharov S.F. Meditsinskie i sanitarno-gigienicheskie problemy likvidatsii posledstvii radiatsionnykh avarii. Meditsina katastrof 2002; 3-4: 38-42.
  2. Avetisov G.M. Planirovanie mediko-sanitarnogo obespecheniya naseleniya pri radiatsionnoi avarii na atomnoi elektrostantsii: Metodicheskie rekomendatsii. 2-e izd., pererab. i dop. M: VTsMK "Zashchita" 2006.
  3. Onishchenko G.G. Itogi i perspektivy obespecheniya radiatsionnoi bezopasnosti naseleniya Rossiiskoi Federatsii. Radiats gig 2008; 1: 4-10.
  4. Grebenyuk A.N. Zadachi Vsearmeiskogo tsentra meditsiny katastrof po likvidatsii mediko-sanitarnykh posledstvii chrezvychainykh situatsii na khimicheski- i radiatsionno-opasnykh ob''ektakh. Vsearmeiskaya nauchno-prakticheskaya konferentsiya: Materialy. SPb: Izd-vo "Chelovek i zdorov'e" 2008; 41-42.
  5. Turai I. Uroki, kotorye sleduet izvlech' iz meditsinskoi pomoshchi, okazannoi pri nedavnikh radiatsionnykh avariyakh. Med radiol i radiats bezopasnost' 2006; 5: 80-82.
  6. Bushmanov A.Yu., Nadezhina N.M. Opyt lecheniya postradavshikh pri radiatsionnykh avariyakh v Rossii Al'manakh klin med 2006; 10: 33-39.
  7. Butomo N.V., Grebenyuk A.N., Legeza V.I. i dr. Osnovy meditsinskoi radiobiologii SPb: Foliant 2004.
  8. Grebenyuk A.N. Sostoyanie neitrofilov pri radiatsionnykh vozdeistviyakh: Avtoref. dis. … d-ra med. nauk. SPb 2002.
  9. Kotenko K.V., Bushmanov A.Yu. Radiatsionnye avarii tret'ego tysyacheletiya v Rossii (2000-2007 godov) s razvitiem ostrykh luchevykh porazhenii. Vestn Ros VMedA 2008; 3: 23: 39-43.
  10. Summer H., Abraham D. Simultaneously measurement of cell surface and intracellular antigens by multiple flow cytometry. J Immunol Meth 1997; 136: 4: 259-265.
  11. Ketlinskii S.A., Kalinina N.M. Immunologiya dlya vrachei. SPb: Gippokrat 1998.
  12. Pigarevskii V.E. Lizosomal'no-kationnyi test. Klinicheskaya morfologiya neitrofil'nykh granulotsitov. L 1988.
  13. Kaplow L.S. Leukocyte alkaline phosphatase cytochemistry: application and methods. Ann NY Acad Sci 1968; 155: 3: 911-928.
  14. Rook G.A., Steele J., Umar S., Dockrell H.M. A simple method for the solubilisation of reduced NBT and its use as a calorimetric assay for activation of human macrophages by gamma-interferon. J Immunol Methods 1985; 82: 1: 161-167.
  15. Malaise E.P., Lambin P., Joiner M.C. Radiosensitivity of human cell lines to small doses. Rad Res 1994; 127: 25-27.
  16. Solntseva O.S. Mekhanizmy apoptoza kletok immunnoi sistemy u uchastnikov likvidatsii avarii na Chernobyl'skoi AES: Avtoref. dis. … kand. biol. nauk. SPb 1999.

Close metadata

Contact the author
Email
Message
The publishing house "Media Sphere" does not provide treatment services, does not give recommendations on contacting medical institutions and specific specialists, on the prescription of medicines and dietary supplements.

Email Confirmation

An email was sent to test@gmail.com with a confirmation link. Follow the link from the letter to complete the registration on the site.

Email Confirmation

Contact us
If you have any questions, complaints or suggestions, please use this feedback form.
Email
Message
The publishing house "Media Sphere" does not provide treatment services, does not give recommendations on contacting medical institutions and specific specialists, on the prescription of medicines and dietary supplements.
Submit Application

You can become an author of one of our magazines, send a request and we will consider it in during the day.

Name
Phone
E-mail
Message
Login
Registration
E-mail
Password
Forgot Password?

Log in to the site using your account in one of the services

Password recovery
E-mail
Login
Register

We use cооkies to improve the performance of the site. By staying on our site, you agree to the terms of use of cооkies. To view our Privacy and Cookie Policy, please. click here.