The use of photodynamic therapy in the complex treatment of chronic generalized moderate periodontitis

Losev F.F.; Krechina E.K.; Ivanova E.V.; Kuksa E.Yu.; Guseva I.E.

doi:https://doi.org/10.17116/stomat202310202111

Losev F.F.

Central Research Institute of Dentistry and Maxillofacial Surgery

SPIN RSCI: 5140-7140
ORCID: 0000-0002-9448-9614

Krechina E.K.

Central Research Institute of Dentistry and Maxillofacial Surgery

SPIN RSCI: 4860-9768
ORCID: 0000-0003-2936-0707

Ivanova E.V.

Institute for Cellular and Intracellular Symbiosis of Ural Division of RAS

ORCID: 0000-0002-4974-8947

Kuksa E.Yu.

Central Research Institute of Dentistry and Maxillofacial Surgery

ORCID: 0000-0001-7628-8678

Guseva I.E.

Central Research Institute of Dentistry and Maxillofacial Surgery

SPIN RSCI: 6381-8364
ORCID: 0000-0001-6226-4819

The use of photodynamic therapy in the complex treatment of chronic generalized moderate periodontitis

Authors:

Losev F.F., Krechina E.K., Ivanova E.V., Kuksa E.Yu., Guseva I.E.

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Journal: Stomatology. 2023;102(2): 11‑15

DOI: 10.17116/stomat202310202111

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To cite this article:

Losev FF, Krechina EK, Ivanova EV, Kuksa EYu, Guseva IE. The use of photodynamic therapy in the complex treatment of chronic generalized moderate periodontitis. Stomatology. 2023;102(2):11‑15. (In Russ.)
https://doi.org/10.17116/stomat202310202111

Подписка 2026 Стоматология (Stomatology)

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OBJECTIVE

Improving the effectiveness of the treatment of chronic generalized periodontitis by photodynamic therapy (PDT) due to clinical and functional validation of the effects of a photosensitizer.

MATERIAL AND METHODS

A clinical and functional study and treatment of moderate chronic generalized periodontitis was carried out in 60 people (24 males and 36 females) aged 35 to 50 years without somatic pathology with orthognathic bite. The patients were divided into 2 groups depending on the type of treatment: group 1 (main) included 30 patients (17 males and 13 females, mean age of patients was 42.5±3.3 years) who received comprehensive treatment consisting of oral sanitation, removal of dental plaque and curettage of periodontal pockets followed by PDT with 1% Geleophor gel using an AFS Spektr LED emitter with a wavelength of 660 nm and a power of 2.5 W, the course consisted of 4 procedures with exposure time of 7 minutes each; group 2 (control) included 30 patients (11 males and 19 females, mean age of patients was 43.0±2.1 years) undergoing standard treatment followed by protective capping with no active therapeutic agent. The state of microcirculation in tissues was studied by the laser Doppler flowmetry (LDF) using the LAKK-M device (Lazma, Russia).

RESULTS

According to LDF data in both groups, it was found that the improvement of microcirculation in periodontal tissues after complex treatment is accompanied by an increase in blood flow and its activity, at that the level of oxygenation and specific oxygen consumption increased more pronounced after PDT, the effect persisted after 6 and 12 months.

CONCLUSION

The use of PDT with LED emitter has a normalizing effect on the state of microcirculation and oxygenation in periodontal tissues.

Keywords:

chronic generalized periodontitis

photodynamic therapy

microcirculation

oxygenation

LED radiation

Authors:

Losev F.F.

Central Research Institute of Dentistry and Maxillofacial Surgery

SPIN RSCI: 5140-7140
ORCID: 0000-0002-9448-9614

Krechina E.K.

Central Research Institute of Dentistry and Maxillofacial Surgery

SPIN RSCI: 4860-9768
ORCID: 0000-0003-2936-0707

Ivanova E.V.

Institute for Cellular and Intracellular Symbiosis of Ural Division of RAS

ORCID: 0000-0002-4974-8947

Kuksa E.Yu.

Central Research Institute of Dentistry and Maxillofacial Surgery

ORCID: 0000-0001-7628-8678

Guseva I.E.

Central Research Institute of Dentistry and Maxillofacial Surgery

SPIN RSCI: 6381-8364
ORCID: 0000-0001-6226-4819

Received:

09.02.2023

Accepted:

27.02.2023

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