Perinatal outcomes of induced pregnancy after single and double embryo transfer

Kalashnikov S.A.; Sichinava L.G.; Konoplyannikov A.G.; Papysheva E.I.

doi:https://doi.org/10.17116/rosakush20232301164

Kalashnikov S.A.

N.I. Pirogov Russian National Research Medical University

Sichinava L.G.

N.I. Pirogov Russian National Research Medical University

Konoplyannikov A.G.

Pirogov Russian National Research Medical University

Papysheva E.I.

N.E. Bauman City Clinical Hospital No29

Perinatal outcomes of induced pregnancy after single and double embryo transfer

Authors:

Kalashnikov S.A., Sichinava L.G., Konoplyannikov A.G., Papysheva E.I.

More about the authors

Journal: Russian Bulletin of Obstetrician-Gynecologist. 2023;23(1): 64‑69

DOI: 10.17116/rosakush20232301164

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To cite this article:

Kalashnikov SA, Sichinava LG, Konoplyannikov AG, Papysheva EI. Perinatal outcomes of induced pregnancy after single and double embryo transfer. Russian Bulletin of Obstetrician-Gynecologist. 2023;23(1):64‑69. (In Russ.)
https://doi.org/10.17116/rosakush20232301164

Подписка 2026 Российский вестник акушера-гинеколога (Russian Bulletin of Obstetrician-Gynecologist)

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OBJECTIVE

To evaluate the perinatal outcomes of induced pregnancy after single and double embryo transfer.

MATERIAL AND METHODS

A total of 325 patients were examined: 59 patients had 1 embryo transferred, resulting in a singleton pregnancy (Group 1); 266 patients had 2 embryos transferred, resulting in twins (Group 2). Perinatal outcomes were evaluated in the two groups.

RESULTS

The incidence of threatened abortion of pregnancy in the first trimester (37.3 and 59.8%, respectively) and in the second trimester (30.5 and 49.2%, respectively), spontaneous abortion (1.7 and 3.4%), isthmico-cervical insufficiency (10.2 and 17.7%), preterm labor in 32—36 weeks (14, 3 and 46.3%), early and extremely early preterm births before 31 weeks (0 and 13.2%), fetal growth retardation (one or both) (6.9 and 46.2%), pre-eclampsia (17.2 and 35.8%), anemia in the first trimester (13.6 and 29.3%) and in the second and third trimesters (20.7 and 41.6%), the frequency of cesarean section (32.8 and 80.2%). The incidence of asphyxia (13.8 and 24.4%), morphofunctional immaturity (32.8 and 41.1%), respiratory distress syndrome (27.9 and 42.8%), the need for artificial ventilation (10.3 and 17.1%) and assisted ventilation with continuous positive pressure (10.3 and 18.3%) were lower in Group 1 infants than in Group 2 infants. Perinatal losses were observed only in Group 2 (0 and 6.6%).

CONCLUSION

Perinatal outcomes were better with single embryo transfer, confirming the appropriateness of limiting the number of embryos transferred to one.

Keywords:

IVF

single and double embryo transfer

perinatal outcomes

twins

singleton pregnancy

Authors:

Kalashnikov S.A.

N.I. Pirogov Russian National Research Medical University

Sichinava L.G.

N.I. Pirogov Russian National Research Medical University

Konoplyannikov A.G.

Pirogov Russian National Research Medical University

Papysheva E.I.

N.E. Bauman City Clinical Hospital No29

Received:

15.04.2022

Accepted:

13.05.2022

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