OBJECTIVE

Quantitative analysis of the clinical features of the endometrial polyps (EP) in postmenopausal patients.

MATERIAL AND METHODS

A retrospective cohort study was carried out on the basis of the gynecological department of the private healthcare institution «Russian Railways—Medicine» in Omsk. The study cohort consisted of 133 postmenopausal patients with endometrial polyps (mean age 59.23±6.34 years) who underwent hysteroscopic polypectomy.

RESULTS

The duration of post-menopause was 9.47±6.66 years. EP dominated in late postmenopausal women (95% CI 60.4—76.4%). Patients with endometrial polyps in postmenopausal women had asymptomatic course (95% CI 61.2—77.2%), uterine bleeding (95% CI 22.8—38.8%), recurrent polyps (15.8%), concomitant treatment with tamoxifen (3.8%). According to hysteroscopy data, single endometrial polyps prevailed (95% CI 67.7—82.7%) with an average size of 15.7±9.4 mm. The prevalence of glandular fibrous polyps (61.7%) is characteristic of glandular (36.8%) and adenomatous (1.5%). Signs of malignancy of the endometrial adenomatous polyp and cancer in the surrounding endometrium were found both in symptomatic (n=41) and asymptomatic (n=92) course of the disease (p>0.05).

CONCLUSION

In postmenopausal patients with asymptomatic endometrial polyps and endometrial polyps associated with postmenopausal bleeding the disease proceeds at of pre-cancer and endometrial cancer background (in the polyp or surrounding endometrium) in 3.76% of cases that requires histological verification when detecting the proliferative processes in the endometrium according to ultrasound data regardless the size of the polyp and the absence of clinical manifestations.