Scarring cervical deformity. A modern view of the problem

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Issues related to coarse cervical scarring remain underreported. The anatomical structure and functions of the cervix contribute to the maintenance of normal microbiocenosis, which protects the reproductive system from the introduction of specific and non-specific pathogens. Scarring cervical deformation creates a reservoir for long-term persistence of human papillomavirus and opportunistic and pathogenic microflora, contributing to the chronic recurrence of inflammation in the cervix. Against the background of cervical scarring, precancerous diseases often develop. Reconstructive plastic surgery to restore the structure of the cervical canal contributes to the elimination of chronic endocervicitis without the use of adjuvant therapy, normalization of vaginal microflora, and the state of infectious resistance of the reproductive tract. Any cervical surgery is one element of a comprehensive therapy that includes preoperative preparation for the management of acute inflammatory changes, and the creation of favorable conditions for regeneration, as well as postoperative rehabilitation. A prerequisite for an operation is the elimination of acute inflammatory and neoplastic processes.

Keywords:

uterine cervix

cervical ruptures

inflammatory process

precancerous diseases

surgical treatment

Authors:

Buianova S.N.

Moskovskiĭ oblastnoĭ NII akusherstva i ginekologii

Shchukina N.A.

Moskovskiĭ oblastnoĭ NII akusherstva i ginekologii

Petrosyan E.I.

State Budgetary Institution of Health Care Ministry of the Moscow Region 'Moscow Regional Research Institute of Obstetrics and Gynecology', Moscow, Russia

Dub N.V.

Moskovskiĭ oblastnoĭ NII akusherstva i ginekologii

Kurinova A.N.

State Budgetary Institution of Health Care Ministry of the Moscow Region 'Moscow Regional Research Institute of Obstetrics and Gynecology', Moscow, Russia;
State Budgetary Institution of Health Care Ministry of the Moscow Region 'Moscow Regional Research and Clinical Institute named after M.F. Vladimirskii', Moscow, Russia

List of references:

Badretdinova FF, Glebova NN, Korotkova LA, Khasanov AG, Trubin VB. Obstetric trauma and cicatricial deformity of the cervix. Some controversial issues of the problem (literature review). Nauchnoe obozrenie. Meditsinskie nauki. 2016;5:23-31. (In Russ.) https://science-medicine.ru/pdf/2016/5/924.pdf.
Guide for outpatient care in obstetrics and gynecology. Ed. Serov VN, Sukhikh GT, Prilepskaya VN, Radzinskiy VE. Moscow: GEOTAR-Media. 2016;1136. (In Russ.)
Amirkhanyan AS, Prilepskaya VN, Bairamova GR, Burmenskaya OV, Kostava MN, Asaturova AV. Chronic cervicitis: current diagnostic and treatment options. Akusherstvo i ginekologiya. 2018;4:22-27. (In Russ) https://doi.org/10.18565/aig.2018.4.22-27
Mitra A, MacIntyre DA, Marchesi JR, Lee YS, Bennett PhR, Kyrgiou M. The vaginal microbiota, human papillomavirus infection and cervical intraepithelial neoplasia: what do we know and where are we going next? Microbiome. 2016;4:1:58.
Shen G, Cheng J, Wang Y, Zhou P, Zhang G. Viral DNA load of high-risk human papilloma virus is closely associated with the grade of cervical lesions. Int J Clin Exp Med. 2014;7:12:5826-5831.
Tummers B, Van Der Burg SH. High-risk human papillomavirus targets crossroads in immune signaling. Viruses. 2015;7:5:2485-2506.
Maltseva LI, Farrakhova LN, Akhmetzyanova AV, Nigmatullina NA. Assessment of HPV-associated chronic cervicitis as a risk factor for cervical cancer. Prakticheskaya meditsina. 2012;9:73-76. (In Russ.)
Recommendations for the diagnosis and treatment of human papillomavirus infections of the female genital tract. Official publication of the European Society for Infectious Diseases in Obstetrics and Gynecology. 2001;4;5(Supplement 21).
Nazarova NM, Prilepskaya VN, Sulamanidze LA, Mzarelua GM, Bestayeva NV. Human papillomavirus infection: prevalence, diagnosis and treatment (review). Lechashchiy vrach. 2013;11:15-18. (In Russ.)
Arbyn M, Anttila A, Jordan J, Ronco G, Schenck U, Segnan N, Wiener HG, Herbert A, Daniel J, von Karsa L. European guidelines for quality assurance in cervical cancer screening. 2nd ed. Luxembourg: Office for Official Publications of the European Communities; 2008;324. https://doi.org/10.1093/annonc/mdp471
Rogovskaya SI, Podzolkova NM. Prevention of cervical cancer. Modern strategies. Doktor RU. Prilozhenie po onkologii. 2011;5:24-27. (In Russ.)
Sukhikh GT, Prilepskaya VN, Bebneva TN, Galitskaya MG, Zarochentseva NV, Kozachenko VP, Kolomiyets LA, Kostava MN, Krasnopol’skiy VI, Kuevda DA, Meshkova RYa, Minkina GN, Namazova-Baranova LS, Podzolkova NM, Rogovskaya SI, Savicheva AM, Tatochenko VK, Urmancheeva AF, Kharit SM, Shabalova IP, Shakhanina IL, Shipitsyna EV, Shipulina OYu. A guide for doctors. Prevention of cervical cancer. Moscow. M: MEDpress-Inform. 2012;192. (In Russ.)
Rogovskaya S.I. Practical colposcopy. Moscow: GEOTAR-Media, 2011;232. (In Russ.)
Kulavskiy VA, Nasyrova SF, Tkachenko VN, Khairullina FL, Arkhipov VV, Galimov RR. The significance of morphological research methods in the diagnosis of cervical pathology. Meditsinskii vestnik Bashkortostana. 2014;2:5:77-80. (In Russ.) https://cyberleninka.ru/article/v/znachenie-morfologicheskih-metodov-issledovaniya-v-diagnostike-patologii-sheyki-matki
Ashyrbekova VB, Dolgaya GV. Treatment of benign diseases of the cervix uteri (literature review). Vestnik KRSU. 2014;14:32-35. (In Russ)
Andosova LD, Kontorshchikova KN, Kachalina OV. Early diagnosis methods and new screening technologies for cervical diseases. Meditsinskii Al’manakh. 2011;19:6:98-102. (In Russ.)
Cervix, vagina, vulva. Physiology, pathology, colposcopy, esthetic correction: manual for practitioners. Eds. Rogovskaya SI, Lipova EV. Moscow: Status Praesens, 2014;832. (In Russ.)
Ultrasound diagnosis in obstetrics and gynecology. Translat. from Engl. Eds. Hus A.I., Smith N.Ch., Smith E.M. Moscow: Prakticheskaya meditsina. 2010;304. (In Russ.)
Kondrikov NI, Barinova IV. Pathology of the uterus. A guide for doctors. 2nd ed. Prakticheskaya meditsina. 2019;352. (In Russ.)
Ekzo- and endocervicitis: morphological aspects. Polyclinic gynecology. Ed. Prilepskaya VN, Kondrikov NI. Moscow: MEDpress-inform, 2004;624:47-56. (In Russ.)
Sashkina AE, Popkov SA, Demicheva NV, Pustovalov DA, Bulgakova SA. Errors in the choice of treatment tactics for patients with cervical pathology on the background of its deformation. Collection of proceedings of the scientific conference 'Actual issues of clinical medicine'. Moscow. 2005;129-131. (In Russ.)
Kostava ME. The role of inflammation in the diagnosis and treatment of cervical pathology. Moscow: SC obstetrics, gynecology, perinatology RAMS. (In Russ)
Baskakov PN, Osmanov EM, Petrova OP, Zalinyan MV. Diagnosis and treatment of cicatricial deformity of the cervix. Zdorov’ye zhenshchiny. Simferopol´. 2011;2:58. (In Russ.)
Sidorova IS, Levakov SA. Background and precancerous processes of the cervix. Moscow: MIA, 2006;96. (In Russ.)
Rusakevich PS, Litvinova TM. Cervical disease in pregnant women: diagnosis, treatment, monitoring, prevention. Moscow. M: MIA, 2006;144. (In Russ.)
Podzolkova NM, Landekhovsky YuD, Kizhaev YuE. Diagnosis and treatment of cicatricial deformity of the cervix. Modern possibilities of reconstructive plastic surgery. Materials of the 9th All-Russian Scientific Forum 'Mother and Child'. Moscow. 2007;488-489. (In Russ.)
Badretdinova FF, Trubina TB, Khasanov AG, Magafurov RF. Some aspects of the prevention and treatment of the effects of obstetric cervical trauma. Treatment and prevention. 2015;2:14:5-10. (In Russ.)
Trubina TB, Trubin VB, Glebova HH. Obstetric injuries of the cervix are risk factors for background and precancerous diseases. Proceedings of the I Russian Congress 'Genital infections and cervical pathology'. Moscow. 2004;220:80-81. (In Russ.)
Laslo Szalay, Ungar L. Cervical pathology. Colposcopy and cytology. Tutorial Cytosza Publishing Gybr Hungary. 2007;444.
Shafi M, Naseer S. Colposcopy. A practical guide. Fivepin ltd. 2006.
Schiffman M, Castle PE. The promise of global cervical-cancer prevention. N Engl J Med. 2005;353:2101-2104.
Kulakov VI, Prilepskaya VN, Radzinskiy VE. Guidelines for outpatient care in obstetrics and gynecology. Moscow: GEOTAR-Media, 2006;1056. (In Russ)
Badretdinova FF, Trubin VB, Dodonov AN. Obstetric uterine cervix injuries in first labor is risk factor for developing uterine cervix background and precancerous diseases. Permskii meditsinskii zhurnal. 2013;30:1:40-45. (In Russ.)
Krasnopol´skiy VI, Buyanova SN, Shchukina NA, Popov AA. Surgical gynecology. Moscow: MEDpress-inform, 2017;320. (In Russ.)
Badretdinova FF, Khasanov AG, Trubin VB. Some aspects of the classification of cicatricial cervical deformity. Obstetrics, gynecology and reproduction. Akusherstvo, ginekologiya i reproduktsiya. 2014;3:41-44. (In Russ.)
Sergeeva YuA, Gustovarova TA, Kuzminykh VV. Cicatricial deformity of the cervix utery: risk factors, remote results of the plastic surgery in fourth stage of labor. Smolenskii meditsinskii Almanakh. 2017;4:42-46. (In Russ.)
Molochkov AV, Bagramova GE, Murakov SV, Maikov OA, Seregina PE, Veredchenko AV, Popkov SA. Immunological aspects of the pathogenesis of chronic endocervicitis in the presence of cicatricial deformity of the cervix uteri. Akusherstvo i ginekologiya. 2014;2:57-59. (In Russ.)
Ziganshin AM, Kulavskiy VA, Kulavskiy EV. The outcome of childbirth and the postpartum period in women who gave birth by cesarean section about a clinically narrow pelvis. Protection of reproductive health of the family: medical and organizational technologies of the XXI century: A collection of scientific papers on the 25th anniversary of the Department of Obstetrics and Gynecology, IPO.Samara: GUSO 'Perspektiva'. 2008;109-112. (In Russ.)
Nasyrova SF, Ziganshin AM, Vdovina TR. Diagnostic of the state of cervix in patients with post-traumatic violations. Sovremennye problemy nauki i obrazovaniya. 2015;6. (In Russ.) https://science-education.ru/pdf/2015/6/473.pdf
Gynecology. National guideline. Eds. Savel’yeva GM, Sukhikh GT, Manukhin IB, Radzinskiy VE. Moscow: GEOTAR-Media, 2017; 1048. (In Russ.)
Van Ostade X, Martin Dom, Van Raemdonck G IPA. Analysis of cervicovaginal fluid from precancerous women points to the presence of biomarkers for the precancerous state of cervical carcinoma. Proteomes. 2014;2:3:426-450. https://doi.org/10.3390/proteomes2030426
Van Raemdonck GA, Tjalma WA, Coen EP, Depuydt CE, Van Ostade XW. Identification of protein biomarkers for cervical cancer using human cervicovaginal fluid. PLoS One. 2014;9:9:e106488.
Meng W, Du R, Wang Y, Chen Z, Ding Y. Human β-defensin messenger RNA is overexpressed in the cervical epithelia of patients with nongonococcal cervicitis. J Low Genit Tract Dis. 2013;17:4:440-445.
Coronado PJ, Fasero M. Colposcopy combined with dynamic spectral imaging. A prospective clinical study. Eur J Obstet Gynecol Reprod Biol. 2016;196:11-16.
Tansarli GS, Skalidis T, Legakis NJ, Falagas ME. Abnormal vaginal flora in symptomatic non-pregnant and pregnant women in a Greek hospital: a prospective study. Eur J Clin Microbiol Infect Dis. 2017;36:2:227-232.
Jahic M, Jahic E. The diagnostic approach to patients with atypical squamous cells of undetermined significance Pap on the cervix. Med Arch. 2016;70:4:296-298.

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