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Lopatina O.V.

Moscow Regional Research Institute of Obstetrics and Gynecology, Moscow, Russia

Balan V.E.

Moskovskiĭ oblastnoĭ NII akusherstva i ginekologii

Tkacheva O.N.

Moscow Regional Research Institute of Obstetrics and Gynecology, Moscow, Russia

Sharashkina N.V.

State Research Center for Preventive Medicine, Ministry of Health of Russia, Moscow, Russia

Zhuravel A.S.

Moscow Regional Research Institute of Obstetrics and Gynecology, Moscow, Russia

Specific features of cellular aging in women in different periods of life

Authors:

Lopatina O.V., Balan V.E., Tkacheva O.N., Sharashkina N.V., Zhuravel A.S.

More about the authors

Journal: Russian Bulletin of Obstetrician-Gynecologist. 2015;15(2): 62‑67

DOI: 10.17116/rosakush201515262-67

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Table of contents

SPECIFIC FEATURES OF CELLULAR AGING IN WOMEN IN DIFFERENT PERIODS OF LIFE
SPECIFIC FEATURES OF CELLULAR AGING IN WOMEN IN DIFFERENT PERIODS OF LIFE

To cite this article:

Lopatina OV, Balan VE, Tkacheva ON, Sharashkina NV, Zhuravel AS. Specific features of cellular aging in women in different periods of life. Russian Bulletin of Obstetrician-Gynecologist. 2015;15(2):62‑67. (In Russ.)
https://doi.org/10.17116/rosakush201515262-67

 
Подписка 2026 Российский вестник акушера-гинеколога (Russian Bulletin of Obstetrician-Gynecologist)
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Abstract:

The paper reviews the data available in the literature on the problems of cellular aging in women in different periods of life and a relationship of their health factors, a cardiovascular risk, and telomere biology. It considers the possible factors of women’s health, which influence the development of cardiovascular diseases, type 2 diabetes mellitus, insulin resistance, metabolic syndrome, atherosclerosis, neurological, musculoskeletal diseases, etc. in women in different periods of life. These factors are age at menarche, miscarriage, artificial abortion, preterm delivery, preeclampsia, gestational diabetes, and menopause. The study results establishing the association of women’s health factors with the development of cardiovascular diseases are given. The paper also shows the role of estrogen deficiency in the development of cardiovascular diseases and its impact on telomerase activity and telomere length in postmenopausal women. The authors declare no conflicts of interest.

Keywords:

telomere biology
cardiovascular diseases
menarche
pregnancy complications
reproductive losses
insulin resistance
metabolic syndrome

Authors:

Lopatina O.V.

Moscow Regional Research Institute of Obstetrics and Gynecology, Moscow, Russia

Balan V.E.

Moskovskiĭ oblastnoĭ NII akusherstva i ginekologii

Tkacheva O.N.

Moscow Regional Research Institute of Obstetrics and Gynecology, Moscow, Russia

Sharashkina N.V.

State Research Center for Preventive Medicine, Ministry of Health of Russia, Moscow, Russia

Zhuravel A.S.

Moscow Regional Research Institute of Obstetrics and Gynecology, Moscow, Russia

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