Objective. To improve the follow-up and management tactics in pregnant women with active and clinically cured pulmonary tuberculosis, by examining the results of a comparative analysis of clinical and laboratory findings in these patients. Subject and methods. A comparative retrospective cohort study was conducted in 59 pregnant women with active pulmonary tuberculosis, 143 pregnant women with clinically cured pulmonary tuberculosis, and 143 apparently healthy (nontuberculosis) pregnant women. The investigation used conventional clinical laboratory examinations and liver, kidney, and blood coagulation system function tests. Results. Seeking antenatal care for pregnancy late, irregular visits to an obstetric/gynecologist, and insufficient examination for infectious diseases on admission to a maternity hospital were observed in the pregnant women with active pulmonary tuberculosis. The pregnant women with pulmonary tuberculosis were found to have iron-deficiency anemia, hyperenzymemia as a manifestation of hepatocyte membrane injury, and low serum iron and total protein levels. Those with active pulmonary tuberculosis showed changes in the hemostatic system as the higher values of prothrombin time, fibrinogen, and soluble fibrin monomer complexomes. In the pregnant women with clinically cured pulmonary tuberculosis, the clinical laboratory parameters were similar to those in healthy pregnant women. Conclusion. Anemia and intensified intravascular coagulation processes found in the pregnant women with active pulmonary tuberculosis require appropriate correction of their examination and treatment.