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Rogozhina I.E.

Kafedra akusherstva i ginekologii fakul'teta povysheniia kvalifikatsii i poslediplomnoĭ podgotovki spetsialistov Saratovskogo meditsinskogo universiteta im. V.I. Razumovskogo

Khvorostukhina N.F.

Kafedra akusherstva i ginekologii fakul'teta povysheniia kvalifikatsii i poslediplomnoĭ podgotovki spetsialistov Saratovskogo meditsinskogo universiteta im. V.I. Razumovskogo

Stoliarova U.V.

Kafedra akusherstva i ginekologii fakul'teta povysheniia kvalifikatsii i poslediplomnoĭ podgotovki spetsialistov Saratovskogo meditsinskogo universiteta im. V.I. Razumovskogo

Neĭfel'd I.V.

Kafedra akusherstva i ginekologii fakul'teta povysheniia kvalifikatsii i poslediplomnoĭ podgotovki spetsialistov Saratovskogo meditsinskogo universiteta im. V.I. Razumovskogo

Cytokine profile in patients with myoma of the uterus undergoing its artery embolization

Authors:

Rogozhina I.E., Khvorostukhina N.F., Stoliarova U.V., Neĭfel'd I.V.

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Journal: Russian Bulletin of Obstetrician-Gynecologist. 2011;11(4): 17‑20

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To cite this article:

Rogozhina IE, Khvorostukhina NF, Stoliarova UV, Neĭfel'd IV. Cytokine profile in patients with myoma of the uterus undergoing its artery embolization. Russian Bulletin of Obstetrician-Gynecologist. 2011;11(4):17‑20. (In Russ.)

 
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The results of an investigation of the cytokines IL-1β, IL-2, IL-4, IL-6, γ-INF, TNF-α, and FasL were analyzed in patients with hemorrhagic syndrome-complicated uterine myoma undergoing selective uterine artery embolization (a study group, n=48) or abdominal supracervical hysterectomy (a comparison group, n=65). A control group consisted of 30 apparently healthy women. Postoperative examinations revealed significant increases in the serum concentration of proinflammatory cytokines and the apoptotic marker FasL. There is evidence that uterine artery embolization has a mediated effect on individual components of the immune system in patients with uterine myoma, which suggests that this procedure has certain advantages over hysterectomy for hemorrhage.

Keywords:

uterine myoma
cytokines
uterine artery embolization

Authors:

Rogozhina I.E.

Kafedra akusherstva i ginekologii fakul'teta povysheniia kvalifikatsii i poslediplomnoĭ podgotovki spetsialistov Saratovskogo meditsinskogo universiteta im. V.I. Razumovskogo

Khvorostukhina N.F.

Kafedra akusherstva i ginekologii fakul'teta povysheniia kvalifikatsii i poslediplomnoĭ podgotovki spetsialistov Saratovskogo meditsinskogo universiteta im. V.I. Razumovskogo

Stoliarova U.V.

Kafedra akusherstva i ginekologii fakul'teta povysheniia kvalifikatsii i poslediplomnoĭ podgotovki spetsialistov Saratovskogo meditsinskogo universiteta im. V.I. Razumovskogo

Neĭfel'd I.V.

Kafedra akusherstva i ginekologii fakul'teta povysheniia kvalifikatsii i poslediplomnoĭ podgotovki spetsialistov Saratovskogo meditsinskogo universiteta im. V.I. Razumovskogo

List of references:

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  2. Dobrokhotova Yu.E., Kapranov S.A., Bobrov B.Yu. i dr. Embolizatsiya matochnykh arterii pri lechenii miomy matki. Ros med zhurn 2006;2:23-25.
  3. Kapranov S.A. Embolizatsiya matochnykh arterii pri miome matki kak al'ternativa khirurgicheskomu lecheniyu. Mezhdunar med zhurn 2005;1:74-79.
  4. Kulakov V.I., Manukhin I.B., Savel'eva G.M. Ginekologiya: Natsional'noe rukovodstvo. M: GEOTAR-Media 2007;345-348.
  5. Mishieva O.I., Breusenko V.G., Golukhov G.N. i dr. Effektivnost' i ekonomicheskie zatraty primeneniya embolizatsii matochnykh arterii u bol'nykh s submukoznoi miomoi matki. Ros vestn akush-gin 2008;4:71-76.
  6. Savel'eva G.M., Breusenko V.G., Kapranov S.A. Embolizatsiya matochnykh arterii v lechenii miomy matki, sovremennoe sostoyanie voprosa. Zhurn akush i zhen bol 2010;59:2:81-87.
  7. Sidorova I.S., Levakov S.A. Sovremennyi vzglyad na patogenez miomy matki. Akush i gin 2006;30-33 (prilozhenie).
  8. Tikhomirov A.L., Lubnin D.M. Mioma matki. M: MIA 2006;176.
  9. Tikhomirov A.L., Oleinik Ch.G. Differentsirovannyi podkhod k lecheniyu bol'nykh miomoi matki. Vopr gin akush i perinatol 2008;7:3:74-81.
  10. Fukunaga T., Kidokoro A., Fukunaga M. et al. Kinetics of cytokines and PMN-E in thoracoscopic esophaectomy. Surg Endosc 2003;15:12:1484-1487.
  11. Goodvin S.C. Uterine artery embolization versus myomectomy: a multicenter comparative study. Fertil Steril 2006;85:1:14-21.
  12. Kroenke T.J. Acrylamido polyvinyl microsphere for uterine artery embolisation: 12-month and MR imading results. J Vasc Int Radiol 2008;19:47-57.

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