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Serebryakova I.Yu.

Research and Clinical Department of the Diseases of Upper Respiratory Tracts, Research and Clinical Centre of Otorhinolaryngology, Russian Federal Medico-Biological Agency, Moscow, Russia

Kim I.A.

Kafedra otorinolaringologii RMAPO, Moskva

Nosulia E.V.

Korobkin A.S.

Research Clinical Centre of Otorhinolaryngology, Russian Federal Medico-Biological Agency, Moscow, Russia

Vasomotor rhinitis. The novdel diagnostic modalities

Authors:

Serebryakova I.Yu., Kim I.A., Nosulia E.V., Korobkin A.S.

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Journal: Russian Rhinology. 2018;26(4): 40‑44

DOI: 10.17116/rosrino20182604140

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To cite this article:

Serebryakova IYu, Kim IA, Nosulia EV, Korobkin AS. Vasomotor rhinitis. The novdel diagnostic modalities. Russian Rhinology. 2018;26(4):40‑44. (In Russ.)
https://doi.org/10.17116/rosrino20182604140

 
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The number of the patients presenting with various forms of rhinitis grows steadily throughout the world. Etiology, pathogenesis, and diagnostics of vasomotor rhinitis remain unclear. Aim. The objective of the present study was the search of the methods for the enhancement of the effectiveness of the treatment of vasomotor rhinitis. Materials and methods. The differential exfoliative cytological analysis of nasal secretion from each half of the nasal cavity, evaluation of the activity of myeloperoxidases present in the secretion with the use of the nitro-blue tetrazolium reduction (NBT) test for the assessment of the functional activity of neutrophils as the pre-immune protective factor, immunological analysis of the blood including the measurement of the Ig A, IgM, IgG, and IgE levels with the use of the Mancini radial immunodiffusion assay, and histological examination of intranasal mucosa. Conclusion. The measurement of the activity of myeloperoxidases present in the nasal secretion is currently the sole objective method for diagnostics of vasomotor rhinitis.

Keywords:

chronic rhinitis
vasomotor rhinitis
differential diagnostics
nasal secretion
myeloperoxidase activity
exfoliative cytological analysis

Authors:

Serebryakova I.Yu.

Research and Clinical Department of the Diseases of Upper Respiratory Tracts, Research and Clinical Centre of Otorhinolaryngology, Russian Federal Medico-Biological Agency, Moscow, Russia

Kim I.A.

Kafedra otorinolaringologii RMAPO, Moskva

Nosulia E.V.

Korobkin A.S.

Research Clinical Centre of Otorhinolaryngology, Russian Federal Medico-Biological Agency, Moscow, Russia

List of references:

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  2. Bousquet J, Khaltaev N, Cruz AA, Denburg J, Fokkens WJ, Togias A, Zuberbier T, Baena-Cagnani CE, Canonica GW, Van Weel C, Agache I, Aït-Khaled N, Bachert C, Blaiss MS, Bonini S, Boulet LP, Bousquet PJ, Camargos P, Carlsen KH, Chen Y. Allergic Rhinitis and its Impact on Asthma (ARIA) 2008. Allergy. 2008;63(86):8-160. https://doi.rg/10.1111/j.1398-9995.2007.01620.x
  3. Blaiss MS. Allergic rhinitis: Direct and indirect costs. Allergy and Asthma Proceedings. 2010;31(5):375-380. https://doi.org/10.2500/aap.2010.31.3329
  4. Bousquet J, Fokkens W, Burney P, Durham SR, Bachert C, Akdis CA, Canonica GW, Dahlen SE, Zuberbier T, Bieber T, Bonini S, Bousquet PJ, Brozek JL, Cardell LO, Crameri R, Custovic A, Demoly P. Important research questions in allergy and related diseases: nonallergic rhinitis: a GA2LEN paper. Allergy. 2008;63(7):842-853. https://doi.org/10.1111/j.1398-9995.2008.01715.x
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  6. Serebryakova IYu. Issledovaniye kachestva zhizni u bolnykh khronicheskim gipertroficheskim rinitom. Vserossiiskaya nauchno-prakticheskaya konferentsiya s mezhdunarodnym uchastiyem «Sovremennyye aspekty i perspektivy razvitiya otorinolaringologii»; M., Sentyabr’ 29—30, 2005. (In Russ.)
  7. Dainyak LB. Vazomotornyi rinit. M.: Meditsina; 1966. (In Russ.)
  8. Bykova V.P. Imunnomorfologiya allergicheskogo rinita (kletochno-molekulyarnyi aspekt). Vestnik otorinolaringologii. 2002;4:59-62. (In Russ.)
  9. Kim IA. Nosulya EV. Sovershenstvovaniye patogeneticheskoy korrektsii posleoperatsionnykh izmeneniy slizistoy obolochki nosa v sovremennoy rinokhirurgii. Rossiyskaya otorinolaringologiya. 2009;1(38):184-187. (In Russ.)
  10. Corey JP. Vasomotor rhinitis should not be a wastebasket diagnosis. Archives of Otolaryngology — Head & Neck Surgery. 2003;129(5):588-589. https://doi.org/10.1001/archotol.129.5.588
  11. Piskunov GZ, Piskunov SZ. Klinicheskaya rinologiya. 2-e izd. M.: MIA; 2006. (In Russ.)

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