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Tsukanov V.V.

Krasnoyarsk Science Center of the Siberian Branch of the Russian Academy of Sciences — a separate subdivision «Scientific Research Institute of medical problems of the North»

Ryabokon A.G.

Krasnoyarsk Science Center of the Siberian Branch of the Russian Academy of Sciences — a separate subdivision «Scientific Research Institute of medical problems of the North»

Tonkikh Yu.L.

Krasnoyarsk Science Center of the Siberian Branch of the Russian Academy of Sciences — a separate subdivision «Scientific Research Institute of medical problems of the North»

Vasyutin A.V.

Krasnoyarsk Science Center of the Siberian Branch of the Russian Academy of Sciences — a separate subdivision «Scientific Research Institute of medical problems of the North»

Colorectal cancer: incidence, risk factors, and screening

Authors:

Tsukanov V.V., Ryabokon A.G., Tonkikh Yu.L., Vasyutin A.V.

More about the authors

Journal: Russian Journal of Preventive Medicine. 2024;27(3): 93‑97

DOI: 10.17116/profmed20242703193

Read: 2216 times

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Table of contents

COLORECTAL CANCER: INCIDENCE, RISK FACTORS, AND SCREENING
COLORECTAL CANCER: INCIDENCE, RISK FACTORS, AND SCREENING

To cite this article:

Tsukanov VV, Ryabokon AG, Tonkikh YuL, Vasyutin AV. Colorectal cancer: incidence, risk factors, and screening. Russian Journal of Preventive Medicine. 2024;27(3):93‑97. (In Russ.)
https://doi.org/10.17116/profmed20242703193

Подписка 2026 Профилактическая медицина (Russian Journal of Preventive Medicine)
МСФ на ЯМ
Использование инфографики авторами научных работ
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Abstract:

The analysis of the current literature data characterizing the incidence, risk factors and screening methods of colorectal cancer (CRC) is presented. In recent years, dynamics of CRC epidemiological indicators have been unfavorable worldwide. The CRC incidence in Russia is high and reaches 30.7 per 100 thousand population in men, among women — 20.9 per 100 thousand population. The leading risk factors for this pathology include male sex, age older than 45—50 years, detection of adenomatous polyps in the intestines, the presence of close relatives with CRC, obesity, tobacco smoking, alcohol use, consumption of red and processed meat. The leading CRC screening methods are highly sensitive stool occult blood tests and colonoscopy. It is advisable to increase the use of screening and the development of preventive measures to reduce the incidence of CRC in Russia.

Keywords:

colorectal cancer
incidence
risk factors
screening
prevention

Authors:

Tsukanov V.V.

Krasnoyarsk Science Center of the Siberian Branch of the Russian Academy of Sciences — a separate subdivision «Scientific Research Institute of medical problems of the North»

Ryabokon A.G.

Krasnoyarsk Science Center of the Siberian Branch of the Russian Academy of Sciences — a separate subdivision «Scientific Research Institute of medical problems of the North»

Tonkikh Yu.L.

Krasnoyarsk Science Center of the Siberian Branch of the Russian Academy of Sciences — a separate subdivision «Scientific Research Institute of medical problems of the North»

Vasyutin A.V.

Krasnoyarsk Science Center of the Siberian Branch of the Russian Academy of Sciences — a separate subdivision «Scientific Research Institute of medical problems of the North»

Received:

10.07.2023

Accepted:

04.10.2023

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References:

  1. Mattiuzzi C, Lippi G. Current Cancer Epidemiology. Journal of Epidemiology and Global Health. 2019;9(4):217-222.  https://doi.org/10.2991/jegh.k.191008.001
  2. Sung H, Ferlay J, Siegel RL, et al. Global Cancer Statistics 2020: GLOBOCAN Estimates of Incidence and Mortality Worldwide for 36 Cancers in 185 Countries. CA: a Cancer Journal for Clinicians. 2021;71(3):209-249.  https://doi.org/10.3322/caac.21660
  3. Morgan E, Arnold M, Gini A, et al. Global burden of colorectal cancer in 2020 and 2040: incidence and mortality estimates from GLOBOCAN. Gut. 2023;72(2):338-344.  https://doi.org/10.1136/gutjnl-2022-327736
  4. Bogomolova IA, Antoneeva II, Abakumova TV, Gening TP. Population characteristics of colorectal cancer in the Ulyanovsk region according to the regional cancer register. Koloproktologija. 2021;20(2):97-104. (In Russ.). https://doi.org/10.33878/2073-7556-2021-20-2-97-104
  5. Maksimova PE, Golubinskaya EP, Seferov BD, Zyablitskaya EYu. Colorectal cancer: epidemiology, carcinogenesis, molecular subtypes and cellular mechanisms of therapy resistance (analytical review). Koloproktologija. 2023; 22(2):160-171. (In Russ.). https://doi.org/10.33878/2073-7556-2023-22-2-160-171
  6. Siegel RL, Miller KD, Goding Sauer A, et al. Colorectal cancer statistics, 2020. CA: a Cancer Journal for Clinicians. 2020;70(3):145-164.  https://doi.org/10.3322/caac.21601
  7. Araghi M, Soerjomataram I, Bardot A, et al. Changes in colorectal cancer incidence in seven high-income countries: a population-based study. The lancet. Gastroenterology and Hepatology. 2019;4(7):511-518.  https://doi.org/10.1016/S2468-1253(19)30147-5
  8. Sung H, Siegel RL, Rosenberg PS, Jemal A. Emerging cancer trends among young adults in the USA: analysis of a population-based cancer registry. The Lancet. Public Health. 2019;4(3):e137-e147. https://doi.org/10.1016/S2468-2667(18)30267-6
  9. Vuik FE, Nieuwenburg SA, Bardou M, et al. Increasing incidence of colorectal cancer in young adults in Europe over the last 25 years. Gut. 2019;68(10): 1820-1826. https://doi.org/10.1136/gutjnl-2018-317592
  10. Arnold M, Abnet CC, Neale RE, et al. Global Burden of 5 Major Types of Gastrointestinal Cancer. Gastroenterology. 2020;159(1):335-349.e15.  https://doi.org/10.1053/j.gastro.2020.02.068
  11. Arnold M, Sierra MS, Laversanne M, et al. Global patterns and trends in colorectal cancer incidence and mortality. Gut. 2017;66(4):683-691.  https://doi.org/10.1136/gutjnl-2015-310912
  12. Li H, Boakye D, Chen X, et al. Association of Body Mass Index With Risk of Early-Onset Colorectal Cancer: Systematic Review and Meta-Analysis. The American Journal of Gastroenterology. 2021;116(11):2173-2183. https://doi.org/10.14309/ajg.0000000000001393
  13. Zhuikova LD, Choynzonov EL, Ananina OA, et al. The prevalence of oncological diseases among the population of the Siberia region and the Far East. Zdravoohranenie Rossijskoj Federacii. 2023;67(1):64-71. (In Russ.). https://doi.org/10.47470/0044-197X-2023-67-1-64-71
  14. Hossain MS, Karuniawati H, Jairoun AA, et al. Colorectal Cancer: A Review of Carcinogenesis, Global Epidemiology, Current Challenges, Risk Factors, Preventive and Treatment Strategies. Cancers (Basel). 2022;14(7):1732. https://doi.org/10.3390/cancers14071732
  15. Pizzato M, La Vecchia C, Malvezzi M, et al. Cancer mortality and predictions for 2022 in selected Australasian countries, Russia, and Ukraine with a focus on colorectal cancer. European Journal of Cancer Prevention. 2023; 32(1):18-29.  https://doi.org/10.1097/CEJ.0000000000000762
  16. World Cancer Research Fund/ American Institute for Cancer Research. Continuous update project expert report 2018. Diet, nutrition, physical activity and colorectal cancer. 2018. Accessed January 25, 2024. https://www.wcrf.org/diet-activity-and-cancer/
  17. Liu PH, Wu K, Ng K, et al. Association of obesity with risk of early-onset colorectal cancer among women. JAMA Oncology. 2019;5:37-44.  https://doi.org/10.1001/jamaoncol.2018.4280
  18. Rosato V, Bosetti C, Levi F, et al. Risk factors for young-onset colorectal cancer. Cancer Causes and Control: CCC. 2013;24:335-341.  https://doi.org/10.1007/s10552-012-0119-3
  19. Zheng X, Hur J, Nguyen LH, et al. Comprehensive Assessment of Diet Quality and Risk of Precursors of Early-Onset Colorectal Cancer. Journal of the National Cancer Institute. 2021;113:543-552.  https://doi.org/10.1093/jnci/djaa164
  20. Patel SG, Karlitz JJ, Yen T, et al. The rising tide of early-onset colorectal cancer: a comprehensive review of epidemiology, clinical features, biology, risk factors, prevention, and early detection. The lancet. Gastroenterology and Hepatology. 2022;7:262-274.  https://doi.org/10.1016/S2468-1253(21)00426-X
  21. O’Sullivan DE, Sutherland RL, Town S, et al. Risk factors for early-onset colorectal cancer: a systematic review and meta-analysis. Clinical Gastroenterology and Hepatology. 2022;20:1229-40.e5.  https://doi.org/10.1016/j.cgh.2021.01.037
  22. Chang VC, Cotterchio M, De P, Tinmouth J. Risk factors for early-onset colorectal cancer: a population-based case-control study in Ontario, Canada. Cancer Causes and Control: CCC. 2021;32:1063-1083. https://doi.org/10.1007/s10552-021-01456-8
  23. Driver JA, Gaziano JM, Gelber RP, et al. Development of a risk score for colorectal cancer in men. The American Journal of Medicine. 2007;120(3): 257-263.  https://doi.org/10.1016/j.amjmed.2006.05.055
  24. Steele SR, Park GE, Johnson EK, et al. The impact of age on colorectal cancer incidence, treatment, and outcomes in an equal-access health care system. Diseases of the Colon and Rectum. 2014;57(3):303-310.  https://doi.org/10.1097/DCR.0b013e3182a586e7
  25. Gausman V, Dornblaser D, Anand S, et al. Risk Factors Associated With Early-Onset Colorectal Cancer. Clinical Gastroenterology and Hepatology. 2020;18(12):2752-2759.e2.  https://doi.org/10.1016/j.cgh.2019.10.009
  26. Demb J, Earles A, Martínez ME, et al. Risk factors for colorectal cancer significantly vary by anatomic site. BMJ Open Gastroenterology. 2019;6(1): e000313. https://doi.org/10.1136/bmjgast-2019-000313
  27. Peterson YC. Risk Factors for Colorectal Cancer. MOJ Surgery. 2015;2(2):37-42.  https://doi.org/10.15406/mojs.2015.02.00015
  28. Johnson CM, Wei C, Ensor JE, et al. Meta-analyses of colorectal cancer risk factors. Cancer Causes and Control. 2013;24(6):1207-1222. https://doi.org/10.1007/s10552-013-0201-5
  29. Shin A, Joo J, Bak J, et al. Site-specific risk factors for colorectal cancer in a Korean population. PLoS One. 2011;6(8):e23196. https://doi.org/10.1371/journal.pone.0023196
  30. Anderson AS, Renehan AG, Saxton JM, et al. Cancer prevention through weight control-where are we in 2020? British Journal of Cancer. 2021;124: 1049-1056. https://doi.org/10.1038/s41416-020-01154-3
  31. Wolin KY, Yan Y, Colditz GA, Lee IM. Physical activity and colon cancer prevention: a meta-analysis. British Journal of Cancer. 2009;100(4):611-616.  https://doi.org/10.1038/sj.bjc.6604917
  32. Fedirko V, Tramacere I, Bagnardi V, et al. Alcohol drinking and colorectal cancer risk: an overall and dose-response meta-analysis of published studies. Annals of Oncology. 2011;22(9):1958-1972. https://doi.org/10.1093/annonc/mdq653
  33. Pedersen A, Johansen C, Grønbaek M. Relations between amount and type of alcohol and colon and rectal cancer in a Danish population based cohort study. Gut. 2003;52(6):861-867.  https://doi.org/10.1136/gut.52.6.861
  34. Rossi M, Jahanzaib Anwar M, et al. Colorectal Cancer and Alcohol Consumption-Populations to Molecules. Cancers (Basel). 2018;10(2):38.  https://doi.org/10.3390/cancers10020038
  35. Aykan NF. Red Meat and Colorectal Cancer. Oncology Reviews. 2015;9(1):288.  https://doi.org/10.4081/oncol.2015.288
  36. Bradbury KE, Murphy N, Key TJ. Diet and colorectal cancer in UK Biobank: a prospective study. International Journal of Epidemiology. 2020; 49(1):246-258.  https://doi.org/10.1093/ije/dyz064
  37. Burnett-Hartman AN, Lee JK, Demb J, Gupta S. An Update on the Epidemiology, Molecular Characterization, Diagnosis, and Screening Strategies for Early-Onset Colorectal Cancer. Gastroenterology. 2021;160(4):1041-1049. https://doi.org/10.1053/j.gastro.2020.12.068
  38. Wolf AMD, Fontham ETH, Church TR, et al. Colorectal cancer screening for average-risk adults: 2018 guideline update from the American Cancer Society. CA: a Cancer Journal for Clinicians. 2018;68(4):250-281.  https://doi.org/10.3322/caac.21457
  39. Bray C, Bell LN, Liang H, et al. Colorectal Cancer Screening. WMJ. 2017; 116(1):27-33. 
  40. Ladabaum U, Dominitz JA, Kahi C, Schoen RE. Strategies for Colorectal Cancer Screening. Gastroenterology. 2020;158(2):418-432.  https://doi.org/10.1053/j.gastro.2019.06.043
  41. Read B, Sylla P. Aggressive Colorectal Cancer in the Young. Clinics in Colon and Rectal Surgery. 2020;33(5):298-304.  https://doi.org/10.1055/s-0040-1713747
  42. Strum WB, Boland CR. Characterization and Identification of Colorectal Cancer in Persons Younger Than 50 Years. Clinical Gastroenterology and Hepatology. 2019;17(12):2600-2602. https://doi.org/10.1016/j.cgh.2018.12.003
  43. Kaminski MF, Robertson DJ, Senore C, Rex DK. Optimizing the Quality of Colorectal Cancer Screening Worldwide. Gastroenterology. 2020;158(2):404-417.  https://doi.org/10.1053/j.gastro.2019.11.026
  44. Ransohoff DF, Lang CA. Screening for colorectal cancer with the fecal occult blood test: a background paper. American College of Physicians [see comments]. Annals of Internal Medicine. 1997;126:811-822.  https://doi.org/10.7326/0003-4819-126-10-199705150-00014
  45. Lin JS, Piper MA, Perdue LA, et al. Screening for Colorectal Cancer: A Systematic Review for the U.S. Preventive Services Task Force. Evidence Synthesis No. 135. Rockville, MD: Agency for Healthcare Research and Quality; 2015.
  46. Shaukat A, Mongin SJ, Geisser MS, et al. Long-term mortality after screening for colorectal cancer. The New England Journal of Medicine. 2013;369:1106-1114. https://doi.org/10.1056/NEJMoa1300720
  47. Zorzi M, Fedeli U, Schievano E, et al. Impact on colorectal cancer mortality of screening programmes based on the faecal immunochemical test. Gut. 2015;64:784-790.  https://doi.org/10.1136/gutjnl-2014-307508
  48. Giorgi Rossi P, Vicentini M, Sacchettini C, et al. Impact of screening program on incidence of colorectal cancer: a cohort study in Italy. The American Journal of Gastroenterology. 2015; 110:1359-1366. https://doi.org/10.1038/ajg.2015.240
  49. Chiu HM, Chen SL, Yen AM, et al. Effectiveness of fecal immunochemical testing in reducing colorectal cancer mortality from the One Million Taiwanese Screening Program. Cancer. 2015;121:3221-3229. https://doi.org/10.1002/cncr.29462
  50. Doubeni CA, Corley DA, Quinn VP, et al. Effectiveness of screening colonoscopy in reducing the risk of death from right and left colon cancer: a large community-based study. Gut. 2018;67:291-298.  https://doi.org/10.1136/gutjnl-2016-312712
  51. Kahi CJ, Pohl H, Myers LJ, et al. Colonoscopy and colorectal cancer mortality in the Veterans Affairs health care system: a case-control study. Annals of Internal Medicine. 2018;168:481-488.  https://doi.org/10.7326/M17-0723
  52. Nishihara R, Wu K, Lochhead P, et al. Long-term colorectal-cancer incidence and mortality after lower endoscopy. The New England Journal of Medicine. 2013;369:1095-1105. https://doi.org/10.1056/NEJMoa1301969
  53. Bretthauer M, Løberg M, Wieszczy P, et al. Effect of Colonoscopy Screening on Risks of Colorectal Cancer and Related Death. The New England Journal of Medicine. 2022;387(17):1547-1556. https://doi.org/10.1056/NEJMoa2208375
  54. Knudsen AB, Rutter CM, Peterse EFP, et al. Colorectal cancer screening: an updated modeling study for the US Preventive Services Task Force. JAMA. 2021;325(19):1998-2011. https://doi.org/10.1001/jama.2021.5746
  55. Gupta S. Screening for Colorectal Cancer. Hematology/oncology clinics of North America. 2022;36(3):393-414.  https://doi.org/10.1016/j.hoc.2022.02.001
  56. Gupta S, Lieberman D, Anderson JC, et al. Recommendations for follow-up after colonoscopy and polypectomy: a consensus update by the US Multi-Society Task Force on Colorectal Cancer. Gastroenterology. 2020;158(4):1131-1153. https://doi.org/10.1053/j.gastro.2019.10.026
  57. Kashin SV, Nekhaykova NV, Zav’yalov DV, et al. The colorectal cancer screening: the current global situation and the main standards for the quality of screening colonoscopy recommended by the European Society of Gastrointestinal Endoscopy (ESGE). Dokazatel’naja gastrojenterologija. 2017; 6(4):32-52. (In Russ.). https://doi.org/10.17116/dokgastro20176432-52
  58. Desyatov EN, Aliev FS, Tsvetkov MS, et al. Screening for colorectal cancer in employees of ROSTECH enterprises in the Sverdlovsk region. Pilot project. Koloproktologija. 2023;22(2):64-69. (In Russ.). https://doi.org/10.33878/2073-7556-2023-22-2-64-69
  59. Freisling H, Arnold M, Soerjomataram I, et al. Comparison of general obesity and measures of body fat distribution in older adults in relation to cancer risk: meta-analysis of individual participant data of seven prospective cohorts in Europe. British Journal of Cancer. 2017;116(11):1486-1497. https://doi.org/10.1038/bjc.2017.106
  60. Vieira AR, Abar L, Chan DSM, et al. Foods and beverages and colorectal cancer risk: a systematic review and meta-analysis of cohort studies, an update of the evidence of the WCRF-AICR Continuous Update Project. Annals of Oncology. 2017;28(8):1788-1802. https://doi.org/10.1093/annonc/mdx171
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