Epidemiological features of laryngeal papillomatosis in adults in Moscow

Kryukov AI, Romanenko SG, Oteyami AB, et al. . Epidemiological features of laryngeal papillomatosis in adults in Moscow. Russian Bulletin of Otorhinolaryngology. 2024;89(3):4‑10. (In Russ.)
https://doi.org/10.17116/otorino2024890314

Подписка 2026 Вестник оториноларингологии (Russian Bulletin of Otorhinolaryngology)

Использование инфографики авторами научных работ

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OBJECTIVE

To evaluate the incidence of laryngeal papillomatosis (LP) and LP recurrence in adults and to determine the risk factors for the development of LP recurrence in adults in Moscow. To solve the tasks set, a survey of patients carried out, including the collection of complaints and anamnesis, a standard examination of the ENT organs, an assessment of the condition of the larynx, and a histological examination.

MATERIAL AND METHODS

We conducted a retrospective analysis of the case histories of 299 patients with LP observed and treated at the Sverzhevsky Research and Clinical Institute of Otorhinolaryngology in the period 2010-2020.

RESULTS

On average, over the entire study period, the prevalence of PG was 17.80%. It was found that out of 299 patients, 69.6% (n=208) had a relapse of LP. Papilloma of the larynx were more often localized in the glottis. 275 (92%) patients had a widespread form of LP. LP recurrences were significantly more common in women and in patients with an existing cicatricle process in the larynx. The relapse rate was higher in non-smokers (73.5% vs 47.8%; p<0.001). Although the recurrence rate was higher in patients with non-voice occupations (70.6% vs. 52.9%), there was no statistically significant association between relapses and the vocal professions (p=0.125).

CONCLUSION

As a result of the study, a number of risk factors for laryngeal papillomatosis recurrent have been identified, and their study should be continued.

Keywords:

laryngeal papillomatosis

recurrence

risk factors

Authors:

Kryukov A.I.

Pirogov Russian National Research Medical University;
Sverzhevsky Research Clinical Institute of Otorhinolaryngology

ORCID: 0000-0002-0149-0676

Romanenko S.G.

Sverzhevky Research Clinical Institute of Otorhinolaryngology

SPIN RSCI: 5645-3401
Scopus AuthorID: 14016776700
ORCID: 0000-0002-8202-5505

Oteyami A.B.

Pirogov Russian National Research Medical University

ORCID: 0000-0002-6994-2210

Amegan N.H.

Epidemic Treatment Center

ORCID: 0000-0002-3168-5183

Pavlikhin O.G.

L.I. Sverzhevskiy Research and Clinical Institute of Otorhinolaryngology of the Moscow Healthcare Department

SPIN RSCI: 1319-6290
Scopus AuthorID: 6507315960
ORCID: 0000-0003-3876-093X

Eliseev O.V.

Sverzhevsky Research Clinical Institute of Otorhinolaryngology

ORCID: 0000-0002-3969-1617

Kurbanova D.I.

Sverzhevsky Research Clinical Institute of Otorhinolaryngology

ORCID: 0000-0002-3571-8851

Lesogorova E.V.

Sverzhevsky Research Clinical Institute of Otorhinolaryngology

ORCID: 0000-0003-1753-5960

Received:

04.04.2023

Accepted:

12.12.2023

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