Breast cancer (BC), cervical cancer (CC), and colorectal cancer (CRC) are among the most common malignant neoplasms (MN), accounting for a significant proportion of deaths due to MN in the Russian Federation. The current program of medical checkup of the adult population in the Russian Federation includes several tests aimed at early detection of these MNs.
OBJECTIVE
To evaluate the socio-economic efficiency of the implementation of measures aimed at early detection of cervical, breast, and colorectal cancer as part of the medical check-up program.
MATERIAL AND METHODS
The survival rate and costs of medical check-ups, as well as the subsequent life-long costs due to MN were modelled for the cohort with BC, CC and CRC identified during the medical check-ups in 2019. The same set of variables was forecasted for the situation in the absence of the medical check-up program The values of the parameters for modeling were obtained from the statistical observation data in 2019 and other published data; the costs were estimated as of 2022.
RESULTS
Additional costs associated with cancer screening during the medical check-ups amounted to 1.711.94 million rubles for breast cancer (3.336 life years gained), 902.74 million rubles for cervical cancer (1.734 life years gained), and 2.527.67 million rubles for the CRC (4.354 life years gained). The cost per 1 life year gained ranged from 513.2 to 1.070.6 thousand rubles, depending on the inclusion of costs due to premature death and disability. These results are below the possible limit values for this indicator (the threshold of willingness to pay) in the Russian Federation.
CONCLUSION
The results confirm the socio-economic efficiency and rationality of measures aimed at early detection of breast, cervical, and colorectal cancer included into the medical check-up program.