Association of behavioral risk factors with the development of malignant neoplasms

Kaprin A.D.; Chissov V.I.; Alexandrova L.M.; Starinsky V.V.

doi:https://doi.org/10.17116/profmed202124021109

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Abstract:

Malignant neoplasms (MN) are the second leading cause of global mortality. The dominant role in the etiology of cancer is played by environmental factors and human lifestyle. According to the results of population epidemiological studies up to 70% of cases of oncological morbidity are associated with four potentially modifiable risk factors (RF): tobacco smoking, excessive alcohol consumption, overweight, and insufficient physical activity. The analysis of data from literature devoted to the study of the relationship between behavioral factors and the risk of developing cancer was carried out. The results of the study indicate that a significant proportion of all cases of morbidity and mortality from malignant neoplasia are associated with modifiable RF, where tobacco smoking has been most studied. Further research is needed into the relationship between dietary patterns, obesity and physical activity and the risk of developing cancer. Population prevention of RF allows reducing the incidence and mortality of the population from cancer. For a deeper understanding of the role of potentially preventable RFs in the incidence of cancer it is necessary to conduct multicenter epidemiological studies with subsequent analysis of the generalized base of results.

Keywords:

malignant neoplasms

behavioral risk factors

tobacco

alcohol

overweight

obesity

physical activity

prevention

Authors:

Kaprin A.D.

P.A. Herzen Moscow Oncology Research Institute — Branch of the National Medical Radiology Research Center of Ministry of Russia;
Peoples’ Friendship University of Russia

SPIN RSCI: 1759-8101
Scopus AuthorID: 6602709853
ResearcherID: K-1445-2014
ORCID: 0000-0001-8784-8415

Chissov V.I.

P.A. Herzen Moscow Scientific Research Institute of Oncology

Alexandrova L.M.

P.A. Herzen Moscow Scientific Research Institute of Oncology

Starinsky V.V.

P.A. Herzen Moscow Scientific Research Institute of Oncology

ORCID: 0000-0003-0268-8307

Received:

03.02.2020

Accepted:

10.11.2020

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References:

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