The frequency of chronic kidney disease (CKD) in the structure of noncommunicable diseases is constantly rising. The number of patients on substitutive renal therapy is increasing. The progression of CKD, the development of drug resistance, and anxiety-depressive states during long-term therapy deteriorate the quality of life (QoL) of patients.

OBJECTIVE

To assess the risk of developing fractures and sarcopenia and the QoL of patients with CKD at the outpatient stage.

MATERIALS AND METHODS

Forty (40) patients with established CKD diagnosis were examined at the outpatient stage. The average of patients was 56.5±11.2 years. The examination included total blood count, blood biochemistry, and QoL assessment using the questionnaires: SARC-f (for sarcopenia signs), MMSE (Mini-Mental State Examination), FRAX (fracture risk assessment tool), and EQ-5D (QoL assessment tool). Statistical data processing was performed using the Statistics software; the indicators were considered statistically significant at p<0.05.

RESULTS

75% of patients with CKD had hypertensive disease (hypertensive nephroangiosclerosis) as a comorbidity. 62% (n=87) had anemic syndrome of varying severity. The QoL assessment revealed moderate/high risk of falls and fractures in 15% (n=21), sarcopenia signs in 35% (n=49), and altered mental state with mild/moderate disorders in 67% (n=94) of cases.

CONCLUSION

We established a statistically significant decrease in QoL indicators (physical and psychological components) in patients with CKD at the outpatient stage, as well as a high risk of other pathological conditions (mineral-bone disorders). This evidence urges timely correction of drug and non-drug therapy and close monitoring at the outpatient stage.