Genetic aspects of endometriosis and adenomyosis: a modern view on the problem

Adamyan L.V.; Kuznetsova M.V.; Pivazyan L.G.; Davydova Yu.D.; Trofimov D.Yu.

doi:https://doi.org/10.17116/repro20232904214

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Abstract:

Endometriosis is a benign gynecologic disease characterized by the presence of endometrial-like tissue outside the uterine cavity. The prevalence of this disease reaches 10—15 per cent among women of reproductive age. There is no single accepted theory of the development of both endometriosis and adenomiosis. This paper presents the genetic aspects of their etiology identified over the last decade. The aim of this literature review is to identify the etiological factors of these diseases for further development of methods of early diagnosis, identification of risk factors of development and recurrence, as well as new methods of treatment based on moleculargenetic features of endometriosis and adenomiosis.

Keywords:

endometriosis

adenomyosis

genetic theory

genetics

Authors:

Adamyan L.V.

Moscow State Medical and Dental University named after A.I. Evdokimov

SPIN RSCI: 9836-2713
Scopus AuthorID: 7006372422
ResearcherID: Q-1722-2018
ORCID: 0000-0002-3253-4512

Kuznetsova M.V.

National Medical Research Center for Obstetrics, Gynecology and Perinatology Named After Academician V.I. Kulakov of the Ministry of Healthcare of Russian Federation

ORCID: 0000-0003-3790-0427

Pivazyan L.G.

National medical research center for obstetrics, gynecology and perinatology named after academician V.I. Kulakov

ORCID: 0000-0002-6844-3321

Davydova Yu.D.

I.M. Sechenov First Moscow State Medical University (Sechenov University)

ORCID: 0000-0001-9840-3710

Trofimov D.Yu.

National Medical Research Center for Obstetrics, Gynecology and Perinatology Named After Academician V.I. Kulakov of the Ministry of Healthcare of Russian Federation

ORCID: 0000-0003-0001-1765

Received:

26.06.2023

Accepted:

01.07.2023

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