Modern approach to the evaluation of the quality of oocytes in programs of in vitro fertilization (literarure review)

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OBJECTIVES

1) to analyze the state of the problem of oocyte quality assessment using various modern methods for predicting the outcome of ART procedure; 2) to evaluate the scientific data which represent the connection between the concentration of biomarkers in follicular fluid in different state of ovarian reserve.

MATERIAL AND METHODS

Search for studies published in international and Russian databases and electronic resources (MedLine, EMBASE, eLibrary, cyberleninka) on the problem of evaluating of the quality of oocytes in ART using keywords.

RESULTS AND CONCLUSION

Oocyte quality assessment is currently implemented using several approaches: assessment of the oocyte morphology, mitochondrial DNA (mtDNA) and follicular fluid (FF). All these methods provide information about the development of follicles and the quality of the oocytes. The variety of approaches and the lack of an objective system for the evaluation of the quality of oocytes in order to improve the effectiveness of ART programs justify the need for further research.

Keywords:

infertility

follicular fluid (FF)

oocyte quality

IVF

pregnancy

Authors:

Mikhaylyukova A.S.

Clinic for Assisted Reproductive Technologies «Test-tube babies»

Vartanyan E.V.

Department of Obstetrics and Gynecology of Pirogov Russian National Research Medical University;
Clinic for Assisted Reproductive Technologies «Test-tube babies»

Dobrokhotova Yu.E.

Pirogov Russian National Research Medical University

SPIN RSCI: 2925-9948
Scopus AuthorID: 57188592250
ORCID: 0000-0002-7830-2290

Tsaturova K.A.

Clinic for Assisted Reproductive Technologies «Test-tube babies»

Devyatova E.A.

Clinic for Assisted Reproductive Technologies «Test-tube babies»

S Kuz’micheva V.

Moscow Regional Research Institute of Obstetrics and Gynecology

Received:

10.09.2020

Accepted:

12.12.2020

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