The use of antioxidant therapy as preconceptional care in men

Efremov E.A.

NII urologii Minzdravsotsrazvitiia RF, Moskva

Kasatonova E.V.

Research Institute of Urology and Interventional Radiology N.A. Lopatkin — branch of FSBI NMRRC of the Ministry of Health, 3-rd Parkovaya str. 51, Moscow, Russia,105425

Melnik Ja.I.

Research Institute of Urology and Interventional Radiology N.A. Lopatkin — branch of FSBI NMRRC of the Ministry of Health, 3-rd Parkovaya str. 51, Moscow, Russia,105425

Kastrikin Yu.V.

The department of urology, andrology and oncourology Pirogov Russian National Research Medical University, Ostrovitianov str. 1,Moscow, Russia, 117997.

Khizriev Kh.Z.

Research Institute of Urology and Interventional Radiology N.A. Lopatkin — branch of FSBI NMRRC of the Ministry of Health, 3-rd Parkovaya str. 51, Moscow, Russia,105425

The use of antioxidant therapy as preconceptional care in men

Authors:

Efremov E.A., Kasatonova E.V., Melnik Ja.I., Kastrikin Yu.V., Khizriev Kh.Z.

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Journal: Russian Journal of Human Reproduction. 2018;24(4): 89‑93

DOI: 10.17116/repro20182404189

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To cite this article:

Efremov EA, Kasatonova EV, Melnik JaI, Kastrikin YuV, Khizriev KhZ. The use of antioxidant therapy as preconceptional care in men. Russian Journal of Human Reproduction. 2018;24(4):89‑93. (In Russ.)
https://doi.org/10.17116/repro20182404189

Подписка 2025-2 (Russian Journal of Human Reproduction)

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In this literature review, the effect of complex antioxidant therapy aimed at correcting oxidative stress, replenishing vitamin deficiencies, trace elements and low molecular weight peptides, has been studied, resulting in damage to the DNA of spermatozoa. In turn, low DNA integrity indicators are associated with a decrease in the probability of natural conception, a decrease in the fertilizing capacity of sperm, an increase in the frequency of embryonic developmental disorders and miscarriages, and an increase in the likelihood of developing cancer in neonates.

Keywords:

male infertility

oxidative stress

antioxidant therapy

assisted reproductive technologies

Authors:

Efremov E.A.

NII urologii Minzdravsotsrazvitiia RF, Moskva

Kasatonova E.V.

Research Institute of Urology and Interventional Radiology N.A. Lopatkin — branch of FSBI NMRRC of the Ministry of Health, 3-rd Parkovaya str. 51, Moscow, Russia,105425

Melnik Ja.I.

Research Institute of Urology and Interventional Radiology N.A. Lopatkin — branch of FSBI NMRRC of the Ministry of Health, 3-rd Parkovaya str. 51, Moscow, Russia,105425

Kastrikin Yu.V.

The department of urology, andrology and oncourology Pirogov Russian National Research Medical University, Ostrovitianov str. 1,Moscow, Russia, 117997.

Khizriev Kh.Z.

Research Institute of Urology and Interventional Radiology N.A. Lopatkin — branch of FSBI NMRRC of the Ministry of Health, 3-rd Parkovaya str. 51, Moscow, Russia,105425

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