Evaluation of clinical outcomes of ivf after estrogen priming before controlled ovarian stimulation in patients with a poor response

Kamilova D.P.; Ketyladze T.M.; Gogolevsky P.A.

doi:https://doi.org/10.17116/repro20182404153

Kamilova D.P.

«Mother and Child» Clinic, Moscow, Russia

Ketyladze T.M.

«Mother and Child» Clinic, Moscow, Russia

Gogolevsky P.A.

«Mother and Child» Clinic, Moscow, Russia

Evaluation of clinical outcomes of ivf after estrogen priming before controlled ovarian stimulation in patients with a poor response

Authors:

Kamilova D.P., Ketyladze T.M., Gogolevsky P.A.

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Journal: Russian Journal of Human Reproduction. 2018;24(4): 53‑58

DOI: 10.17116/repro20182404153

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To cite this article:

Kamilova DP, Ketyladze TM, Gogolevsky PA. Evaluation of clinical outcomes of ivf after estrogen priming before controlled ovarian stimulation in patients with a poor response. Russian Journal of Human Reproduction. 2018;24(4):53‑58. (In Russ.)
https://doi.org/10.17116/repro20182404153

Подписка 2026 Проблемы репродукции (Russian Journal of Human Reproduction)

Использование инфографики авторами научных работ

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Abstract:

Objective — to evaluate the outcomes of IVF cycles in patients with a previous poor response to controlled ovarian stimulation (COS) Material and methods. The study contained 85 patients with preliminary priming with estradiol (Oestrogel) and COS with 225—250 IU of gonadotropins and GnRHant from the 5th days stimulation. Results. The results of the study showed that estrogen priming makes it possible to improve the ovarian response to gonadotropins in comparison with the standard protocol with antagonists, which is important in patients with poor response. Conclusion. The observed result of IVF can be a consequence of both synchronization of follicle growth and stimulation of FSH receptors in granulosa cells by estradiol.

Keywords:

IVF

poor response

estrogens

priming

Authors:

Kamilova D.P.

«Mother and Child» Clinic, Moscow, Russia

Ketyladze T.M.

«Mother and Child» Clinic, Moscow, Russia

Gogolevsky P.A.

«Mother and Child» Clinic, Moscow, Russia

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References:

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