BACKGROUND

Perimenopausasal transition in women is characterized by vasomotor and psychoemotional symptoms, sleep disturbance, development of genitourinary menopausal syndrome, dermatological problems that together worsen the quality of life and determine the medico-social significance of the problem. Rosacea, which is based on vascular pathomorphological and pathophysiological changes occurring in presence of already existing somatic diseases, is one of the frequent dermatoses of the perimenopausal period.

OBJECTIVE

Assessment of clinical and anamnestic characteristics of women in perimenopausal period, suffering from rosacea.

MATERIAL AND METHODS

The study involved 97 patients with rosacea, mean age 50.0±2.7 years. The control group included 60 women, mean age 49.0±2.5 years. Within the study group, an additional division into 2 subgroups (pre- and postmenopausal period) was carried out. All women of the study and control groups were examined by physical examination, obstetric-gynecological, somatic and thrombotic history was studied.

RESULTS

Patients with rosacea statistically significantly more often had stage I—II arterial hypertension (OR 2.51, p=0.0377) and history of chronic diseases of the appendages (OR 4.89, p=0.0405) regardless of the stage of perimenopausal transition. Subjects in the postmenopausal period predominantly had moderate and severe papulopustular subtype of rosacea (p=0.0516), while patients with preserved menstrual function were more likely to have erythematotelangiectatic subtype (p=0.0516) with a predominance of mild severity of the disease’s course (p=0.0506).

CONCLUSION

The obtained data show different clinical course and severity of rosacea depending on the perimenopausal period and indicate the need for a comprehensive study of medical history for further patients monitoring together with allied specialists to achieve optimal therapeutic outcome.