Background. The role of anti-inflammatory factors in adhesion formation has not yet been fully established. Objectives. To evaluate the role of serum and peritoneal pro- and anti-inflammatory markers in patients with varying degrees of inflammatory pelvic adhesions. Method. 60 patients were included in 1st group with stage 1-2 adhesions and infertility, 2nd group consisted of 110 patients with pelvic peritoneal adhesions of 3-4 stage and infertility. Diagnosis of adhesions was established by laparoscopy. The control group consisted of 20 healthy women who underwent laparoscopic tubal sterilization. Results. The levels of IL-1, IL-6, sgp130 in serum were significantly lower in controls vs both groups with adhesions. In the serum and in the peritoneal fluid IL-1, IL-6, sgp130 were increased in atients with stage 3-4 compare to the 1-2 stage. Expression of IL-proinflamatornoy factors in peritoneum 1R?, IL-6R, gp130 in patients with peritoneal adhesions 3-4 stage were significantly increased in relation to the stage of 1-2. At the same time, the expression of SOCS1 was (2.8 fold) significantly higher in patients with stage 1-2 compare to patients with stage 3-4 endometriosis. Conclusion. We found imbalance in serum and peritoneal pro- and anti-inflammatory markers in patients with adhesion. Based on our data we have identified tree types of adhesions: with low prevalence proinflamatory reaction over antiinflamatoroy (type 1), with a high prevalence proinflamatonoy reaction over antiinflamatornoy (type 2) and the mixed type (type 3).