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Kravtsova N.S.

Endocrinology Research Centre, Moscow, Russia

Rozhivanov R.V.

FGU Éndokrinologicheskiĭ nauchnyĭ tsentr, Moskva

Kurbatov D.G.

FGU Éndokrinologicheskiĭ nauchnyĭ tsentr, Moskva

Stimulation of a spermatogenesis at men gonadotrophins and an antiestrogen at a pathospermia and infertility

Authors:

Kravtsova N.S., Rozhivanov R.V., Kurbatov D.G.

More about the authors

Journal: Problems of Endocrinology. 2016;62(2): 37‑41

DOI: 10.14341/probl201662237-41

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To cite this article:

Kravtsova NS, Rozhivanov RV, Kurbatov DG. Stimulation of a spermatogenesis at men gonadotrophins and an antiestrogen at a pathospermia and infertility. Problems of Endocrinology. 2016;62(2):37‑41. (In Russ.)
https://doi.org/10.14341/probl201662237-41

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Aim — to investigate the methods of treatment, directed on increase in quantity of spermatozoa in an ejaculate. Material and methods. In investigation was used: chorionic gonadotrophin, anti-estrogen, recombinant preparations FSH, and also their combinations. Results. The worst efficiency (10%) was noted when using monotherapy by preparation HCG. Efficiency of monotherapy by a preparation of clomiphene was higher and made 20% concerning conception, and 63% concerning an oligoteratozoospermiya. Efficiency of the combined therapy of HCG in combination with recombinant FSH was 40% concerning conception, and 87% concerning an oligoteratozoospermiya. Conclusion. At the same time the studied types of the stimulating therapy are effective, safe and don’t lead to development of side effects.

Keywords:

infertility
spermatogenesis
clomifene
gonadotrophins

Authors:

Kravtsova N.S.

Endocrinology Research Centre, Moscow, Russia

Rozhivanov R.V.

FGU Éndokrinologicheskiĭ nauchnyĭ tsentr, Moskva

Kurbatov D.G.

FGU Éndokrinologicheskiĭ nauchnyĭ tsentr, Moskva

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