The site of the Media Sphera Publishers contains materials intended solely for healthcare professionals.
By closing this message, you confirm that you are a certified medical professional or a student of a medical educational institution.

Login
EN
+7 (495) 482-4118
+7 (495) 482-0604

  • © 1998-2025
+7 (495) 482-43-29
EN
All journals
Journal
Year
Year
Search result: 0

Vasil'ev V.S.

Cheljabinskiĭ oblastnoĭ klinicheskiĭ onkologicheskiĭ dispanser

Manturova N.E.

Kafedra plasticheskoĭ i ésteticheskoĭ khirurgii, kosmetologii i kletochnykh tekhnologiĭ GBOU VPO "Rossiĭskiĭ natsional'nyĭ issledovatel'skiĭ meditsinskiĭ universitet im. N.I. Pirogova" Minzdravsotsrazvitiia Rossii

Vasil'ev S.A.

Rossiĭskiĭ nauchnyĭ tsentr khirurgii im. akad. B.V. Petrovskogo RAMN, Moskva

Teryushkova Zh.I.

Chelyabinsk City Hospital, Chelyabinsk, Russia

Biological features of adipose tissue

Authors:

Vasil'ev V.S., Manturova N.E., Vasil'ev S.A., Teryushkova Zh.I.

More about the authors

Journal: Plastic Surgery and Aesthetic Medicine. 2019;(2): 33‑42

DOI: 10.17116/plast.hirurgia201902133

Views: 34418

Downloaded: 1283

Download PDF (RU)
Contact the author
Table of contents

BIOLOGICAL FEATURES OF ADIPOSE TISSUE
BIOLOGICAL FEATURES OF ADIPOSE TISSUE

To cite this article:

Vasil'ev VS, Manturova NE, Vasil'ev SA, Teryushkova ZhI. Biological features of adipose tissue. Plastic Surgery and Aesthetic Medicine. 2019;(2):33‑42. (In Russ.)
https://doi.org/10.17116/plast.hirurgia201902133

Подписка 2025-2 (Plastic Surgery and Aesthetic Medicine)
 
МСФ на ЯМ
Close metadata
Recommended articles:
Auto­logous adipose tissue in treatment of linear scle­roderma in the children (literature review). Plastic Surgery and Aesthetic Medi­cine. 2024;(4-2):91-94
Cell technologies as a basis for the deve­lopment of rege­nerative principles for the treatment of lacrimal gland diseases. Russian Annals of Ophthalmology. 2024;(2-2):158-165
Closing of nasal septum perforation using adipose stro­mal vascular fraction: an expe­rimental study. Russian Bulletin of Otorhinolaryngology. 2024;(2):21-27
Expe­rimental substantiation of medi­cal device design for mechanical processing of adipose tissue. Piro­gov Russian Journal of Surgery. 2024;(12-2):101-108
Treatment of knee osteoarthritis with auto­logous stro­mal-vascular fraction of adipose tissue. Rege­nerative Biotechnologies, Preventive, Digi­tal and Predictive Medi­cine. 2024;(4):27-37
Standardized and scalable method for stro­mal-vascular fraction harvesting from adipose tissue. Rege­nerative Biotechnologies, Preventive, Digi­tal and Predictive Medi­cine. 2024;(4):76-81

Adipose tissue is a biologically active component of human body. Besides fat deposition and participating in body contouring, it is one of the key component of thermoregulation, important element of immune regulation. Adipose tissue produces numerous biologically active molecules. Moreover, adipose tissue is a dynamically functioning endocrine organ releasing various hormones. Some of these hormones directly interact with hypothalamus. Adipose derived stem cells are characterized by advanced differentiation potential with possible differentiation into chondrogenic, neurogenic, osteogenic, myogenic, cardiogenic, vascular, endocrine, hepatic, or haematopoietic cells. These features of adipose derived stem cells open good perspectives for their using with cosmetic and reconstructive indications. Adipose tissue availability for harvesting makes it a perspective substrate for regenerative medicine and tissue engineering.

Keywords:

adipose tissue
stem cells
regenerative medicine

Authors:

Vasil'ev V.S.

Cheljabinskiĭ oblastnoĭ klinicheskiĭ onkologicheskiĭ dispanser

Manturova N.E.

Kafedra plasticheskoĭ i ésteticheskoĭ khirurgii, kosmetologii i kletochnykh tekhnologiĭ GBOU VPO "Rossiĭskiĭ natsional'nyĭ issledovatel'skiĭ meditsinskiĭ universitet im. N.I. Pirogova" Minzdravsotsrazvitiia Rossii

Vasil'ev S.A.

Rossiĭskiĭ nauchnyĭ tsentr khirurgii im. akad. B.V. Petrovskogo RAMN, Moskva

Teryushkova Zh.I.

Chelyabinsk City Hospital, Chelyabinsk, Russia

List of references:

  1. Symonds ME. Adipose tissue biology. 2nd ed. Springer. 2017. https://doi.org/10.1007/978-3-319-52031-5
  2. Harms M, Seale P. Brown and beige fat: development, function and therapeutic potential. Nat Med. 2013 Oct;19(10):1252-1263. https://doi.org/10.1038/nm.3361
  3. Illouz Y-G, Sterodimas A. Adipose stem cells and regenerative medicine. Heidelberg, Dordrecht, London, New York — Library of Congress Control Number 2011;929-933. Springer-Verlag Berlin Heidelberg; 2011. https://doi.org/10.1007/978-3-642-20012-0
  4. Giordano A, Song CK, Bowers RR, Ehlen JC, Frontini A, Cinti S, Bartness TJ. White adipose tissue lacks significant vagal innervation and immunohistochemical evidence of parasympathetic innervation. Am J Physiol Regul Integr Comp Physiol. 2010;291:R1243-R1255. https://doi.org/10.1152/ajpregu.00679.2005
  5. Stanleya S, Pintoa S, Segala J, Pérez CA, Viale A, DeFalco J, Cai X, Heisler LK, Friedman JM. Identification of neuronal subpopulations that project from hypothalamus to both liver and adipose tissue polysynaptically. PNAS. 2010;107(15):7024-7029. https://doi.org/10.1073/pnas.1002790107
  6. Than A, Xu S, Li R, Leow MK, Sun L, Chen P. Angiotensin type 2 receptor activation promotes browning of white adipose tissue and brown adipogenesis. Signal Transduct Target Ther. 2017 Jun;2:17022. https://doi.org/10.1038/sigtrans.2017.22
  7. Mariman EC, Wang P. Adipocyte extracellular matrix composition, dynamics and role in obesity. Cell Mol Life Sci. 2010;67:1277-1292. https://doi.org/10.1007%2Fs00018-010-0263-4
  8. Comley K, Fleck NA. A micromechanical model for the young’s modulus of adipose tissue. Int J Solids Struct. 2010;47:2982-2990. https://doi.org/10.1016/j.ijsolstr.2010.07.001
  9. Fonseca-Alaniz MH, Takada J, Alonso-Vale MI, Lima F.B. Adipose tissue as an endocrine organ: from theory to practice. J Pediatr (Rio J). 2007; 83(Suppl 5):S192-S203. https://doi.org/10.2223/JPED.1709
  10. Wang P, Mariman E, Renes J. The secretory function of adipocytes in the physiology of white adipose tissue. J Cell Physiol. 2008;216:3-13. https://doi.org/10.1002/jcp.21386
  11. Flier JS, Maratos-Flier E. Lasker lauds leptin. Cell. 2010;143:9-12. https://doi.org/10.1016/j.cell.2010.09.021
  12. Wojcik-Gładysz A, Wankowska M, Misztal T, Romanowicz K, Polkowska J. Effect of intracerebroventricular infusion of leptin on the secretory activity of the GnRH/LH axis in fasted prepubertal lambs. Anim Reprod Sci. 2009;114:370-383. https://doi.org/10.1016/j.anireprosci.2008.10.009
  13. Lieb W, Beiser AS, Vasan RS, Tan ZS, Harris TB, Roubenoff R, Auerbach S, DeCarli C, Wolf PA, Seshadri S. Association of plasma leptin levels with incident Alzheimer disease and MRI measures of brain aging. JAMA. 2009;302(23):2565-2572. https://doi.org/10.1001%2Fjama.2009.1836
  14. Lilja M, Rolandsson O, Shaw JE, Pauvaday V, Cameron AJ, Tuomilehto J, Alberti KGMM, Zimmet PZ, Söderberg S. Higher leptin levels in Asian Indians than Creoles and uropids: a potential explanation for increased metabolic risk. Int J Obes (Lond). 2010;34(5):878-885. https://doi.org/10.1038/ijo.2010.19
  15. Moreno-Navarrete JM, Catalan V, Ortega F, Gómez-Ambrosi J, Ricart W, Frühbeck G, Fernández-Real JM. Circulating omentin concentration increases after weight loss. Nutr Metab. 2010;7:27-33. https://doi.org/10.1186/1743-7075-7-27
  16. Benaitreau D, Santos ED, Leneveu MC, Alfaidy N, Feige JJ, de Mazancourt P, Pecquery R, Dieudonné MN. Effects of adiponectin on human trophoblast invasion. J Endocrinol. 2010;207(1):45-53. https://doi.org/10.1677/JOE-10-0170
  17. Shuai B, Shen LS, Yang YP, Xie J, Shou ZX, Wei B. Low plasma adiponectin as a potential biomarker for osteonecrosis of the femoral head. J Rheumatol. 2010;37(10):2151-2155. https://doi.org/10.3899/jrheum.100342
  18. Groth SW. Adiponectin and polycystic ovary syndrome. Biol Res Nurs. 2010;12(1):62-72. https://doi.org/10.1177%2F1099800410371824
  19. Taherimahmoudi M, Ahmadi H, Mehrsai A Pourmand, G. Plasma adiponectin concentration and insulin resistance: role of successful kidney transplantation. Transplant Proc. 2010;42(3):797-800. https://doi.org/10.1016/j.transproceed.2010.03.029
  20. Fang B, Luo S, Song Y, Cao Y. Hemangioblastic characteristics of human adipose tissue-derived adult stem cells in vivo. Arch Med Res. 2009;40(4):311-317. https://doi.org/10.1016/j.arcmed.2009.04.007
  21. Han Y, Wei Y, Wang S, Song Y. Cartilage regeneration using adipose-derived stem cells and the controlled-released hybrid microspheres. Joint Bone Spine. 2010;77(1):27-31. https://doi.org/10.1016/j.jbspin.2009.05.013
  22. Niemeyer P, Fechner K, Milz S, Richter W, Suedkamp NP, Mehlhorn AT, Pearce S, Kasten P. Comparison of mesenchymal stem cells from bone marrow and adipose tissue for bone regeneration in a critical size defect of the sheep tibia and the influence of platelet-rich plasma. Biomaterials. 2010;31(13):3572-3579. https://doi.org/10.1016/j.biomaterials.2010.01.085
  23. Gimble JM, Guilak F, Bunnell BA. Clinical and preclinical translation of cell-based therapies using adipose tissue-derived cells. Stem Cell Res Ther. 2010;1(2):19. https://doi.org/10.1186/scrt19
  24. Murohara T. Autologous adipose tissue as a new source of progenitor cells for herapeutic angiogenesis. J Cardiol. 2009;53(2):155-163. https://doi.org/10.1016/j.jjcc.2009.01.003
  25. Kishi K, Imanishi N, Ohara H, Ninomiya R, Okabe K, Hattori N, Kubota Y, Nakajima H, Nakajima. Distribution of adipose-derived stem cells in adipose tissues from human cadavers. J Plast Reconstr Aesthet Surg. 2010;63(10):1717-1722. https://doi.org/10.1016/j.bjps.2009.10.020
  26. Conde-Green A, de Amorim NF, Pitanguy I. Influence of decantation, washing and centrifugation on adipocyte and mesenchymal stem cell content of aspirated adipose tissue: a comparative study. J Plast Reconstr Aesthet Surg. 2010;63(8):1375-1381. https://doi.org/10.1016/j.bjps.2009.07.018
  27. Khouri RKJr, Khouri RK. Current Clinical Applications of Fat Grafting. Plast Reconstr Surg. 2017 Sep;140(3):466e-486e. https://doi.org/10.1097/PRS.0000000000003648
  28. Gir P, Brown SA, Oni G, Kashefi N, Mojallal A, Rohrich RJ. Fat grafting: Evidence-based review on autologous fat harvesting, processing, reinjection, and storage. Plast Reconstr Surg. 2012;130(1):249-258. https://doi.org/10.1097/PRS.0b013e318254b4d3
  29. Streit L, Jaros J, Sedlakova V, Sedlackova M, Drazan L, Svoboda M, Pospisil J, Vyska T, Vesely J, Hampl A.A Comprehensive in vitro comparison of preparation techniques for fat grafting. Plast Reconstr Surg. 2017 Mar;139(3): 670e-682e. https://doi.org/10.1097/PRS.0000000000003124
  30. Oranges CM, Striebel J, Tremp M, Madduri S, Kalbermatten DF, Harder Y, Schaefer DJ. The preparation of the recipient site in fat grafting: A comprehensive review of the preclinical evidence. Plast Reconstr Surg. 2019;143(4):1099-1107. https://doi.org/10.1097/PRS.0000000000005403
  31. Canizares OJr, Thomson JE, Allen RJJr, Davidson EH, Tutela JP, Saadeh PB, Warren SM, Hazen A. The effect of processing technique on fat graft survival. Plast Reconstr Surg. 2017 Nov;140(5):933-943. https://doi.org/10.1097/PRS.0000000000003812
  32. Luong Q, Huang J, Lee KY. Deciphering White Adipose Tissue Heterogeneity. Biology (Basel). 2019 Apr ;8(2):E23. https://doi.org/10.3390/biology8020023
  33. Starsteva OI, Mel’nikov DI, Istranov AL, Lyundup AV, Krasheninnikov ME, Shekhter AB, Dashtoyan GE, Zaharenko AS, Kirillova KA, Sinelnokov ME. Comparative analysis of the effect of mesenchymal stem cells on viability of autologous fat transplants by histologic examination of fat grafts: in vivo experiment. Annals of plastic, reconstructive and aesthetic surgery. 2018;4:12-17. (In Russ.)
  34. Xiong S, Qiu L, Su Y, Zheng H, Yi C. Paracrine effects of adipose-platelet-rich plasma and platelet-rich fibrin enhance the outcomes of fat grafting: A comparative study. Plast Reconstr Surg. 2019 Jun;143(6):1201e-1212e. https://doi.org/10.1097/PRS.0000000000005624
  35. Vasil’ev SA, Karpov IA, Dimov GP, Teryushkova ZI, Gromov IA, Eremin II. The role of the application of the stromal-vascular fraction of the adipose tissue in plastic surgery. Annals of plastic, reconstructive and aesthetic surgery. 2017;2:82-91. (In Russ.)
  36. Vasilyev VS, Vasilyev YuS,Vasilyev SA, Vasilyev IS, Karpov IA. The possibilities of using fat tissue injection for posttraumatic and postsurgical facial counter defects. Annals of plastic, reconstructive and aesthetic surgery. 2014;4:42-50. (In Russ.)
  37. Vasilyev V, Vasilyev S, Vazhenin A, Teryushkova Z, Vasilyev Yu, Vasilyev I, Semyonova A, Dimov G, Lomakin E. An Algorithm for Treatment of Radiation-Induced Soft Tissue Damage with Products Based on Autologous Adipose Tissue. PRS GO. 2018:6(8S):155-156. https://doi.org/10.1097/01.GOX.0000547029.33601.d4
  38. Vasilyev VS, Vasilyev SA, Vasilyev IS, Karpov IA, Migranova NV. The role of fat grafting in treatment of radiation-induced damage of soft tissues. Vestnik South-Ural state university. 2013;13(2):124-126. (In Russ.)
  39. Vasilyev VS, Vasilyev SA, Vasilyev YuS, Vasilyev IS, Karpov IA, Dubrovskaya NS, Chernova ON, Eremin II, Teryushkova ZhI, Kazantsev IB. The role of fat grafting for breast reconstruction. Annals of plastic, reconstructive and aesthetic surgery. 2018;2:37-53. (In Russ.)
  40. Teryushkova ZhI, Vasilyev VS, Kazachkov EL, Vasilyev SA, Karpov IA, Shishmentsev NB, Vasilyev YuS, Vasilyev IS, Dimov GP, Markina TN. Complete healing of postirradiation rectovaginal fistula with autologous fat grafting (case report). Coloproctology. 2016;57(3):70-75. (In Russ.)
  41. Teryushkova ZhI, Vasilyev VS, Vazhenin AV, Kazachkov EL, Vasilyev SA, Dimov GP, Baturina IL. Treatment of radiation-induced colovaginal fistula with autologous fat grafting. Bashkortostan medical journal. 2017;12(6):96-100. (In Russ.)
  42. Teryushkova ZhI, Vasilyev VS, Vazhenin AV,. Vasilyev SA, Dimov GP, Popkov PN, Stasyuk AA. The study of adipose-derived biomaterial used in the treatment of post-radiation rectal lesions. Bashkortostan medical journal. 2018;13(3):36-42. (In Russ.)
  43. Smyshlyaev IA, Gilfanov SI, Kopylov VA, Gilmutdinov RG, Pulin II, Korsakov IN, Gilmutdinova IR, Petrikina AP, Eremin PS, Kryuchkova OV, Abeltsev VP, Zagorodniy NV, Zorin VL, Vasilyev VS, Pupynin DYu, Eremin II. Safety and effectiveness of intraarticular administration of adipose-derived stromal vascular fraction for treatment of knee articular cartilage degenerative damage:preliminary result of a clinical trial. Traumatology and orthopedics of Russia. 2017;23(3):17-31. (In Russ.) https://doi.org/10.21823/2311-2905-2017-23-3-17-31
  44. Zhou Y, Wang J, Li H, Liang X, Bae J, Huang X, Li Q. Efficacy and Safety of Cell-Assisted Lipotransfer: A Systematic Review and Meta-Analysis. Plast Reconstr Surg. 2016;137(1):44e-57e. https://doi.org/10.1097/PRS.0000000000001981
  45. Grabin S, Antes G, Stark GB, Edith Motschall E, Buroh S, Florian M, Lampert FM. Cell-assisted lipotransfer a critical appraisal of the evidence. Dtsch Arztebl Int. 2015;112(15):255-261. https://doi.org/10.3238/arztebl.2015.0255
  46. Hong KY, Yim S, Kim HJ, Jin US, Lim S, Eo S, Chang H, Minn KW. The Fate of the adipose-derived stromal cells during angiogenesis and adipogenesis after cell-assisted lipotransfer. Plast Reconstr Surg. 2018;141(2):365-375. https://doi.org/10.1097/PRS.0000000000004021
  47. Vallee M, Cote JF, Fradette J. Adipose-tissue engineering: taking advantage of the properties of human adipose-derived stem/stromal cells. Pathol Biol (Paris). 2009;57(4):309-317. https://doi.org/10.1016/j.patbio.2008.04.010
  48. Suszynski TM, Rohrich RJ, Sieber DA, Boyd TG, Thornton JF, Teotia SS, Cunningham BL, Van Beek AL Bioengineered Approach to the Design of a Fat Graft Based on Mathematical Modeling that Predicts Oxygen Delivery. Plast Reconstr Surg. 2019;143(6):1648-1655. https://doi.org/10.1097/PRS.0000000000005626
  49. Jae-Seok E, Soo HJ, Jong-Ock S, Kyung-Hwan J, Nam-Soo K. Extracellular Matrix and 3D printing. Curr Trends Biomedical Eng & Biosci. 2017;2(5):555-596. https://doi.org/10.19080/CTBEB.2017.02.555596
  50. Duisit J, Amiel H, Orlando G, Dedriche A, Behets C, Gianello P, Lengelé B. Face Graft Scaffold Production in a Rat Model. Plast Reconstr Surg. 2018;141(1):95-103. https://doi.org/10.1097/PRS.0000000000003910

Close metadata

Contact the author
Email
Message
The publishing house "Media Sphere" does not provide treatment services, does not give recommendations on contacting medical institutions and specific specialists, on the prescription of medicines and dietary supplements.

Email Confirmation

An email was sent to test@gmail.com with a confirmation link. Follow the link from the letter to complete the registration on the site.

Email Confirmation

Contact us
If you have any questions, complaints or suggestions, please use this feedback form.
Email
Message
The publishing house "Media Sphere" does not provide treatment services, does not give recommendations on contacting medical institutions and specific specialists, on the prescription of medicines and dietary supplements.
Submit Application

You can become an author of one of our magazines, send a request and we will consider it in during the day.

Name
Phone
E-mail
Message
Login
Registration
E-mail
Password
Forgot Password?

Log in to the site using your account in one of the services

Password recovery
E-mail
Login
Register

We use cооkies to improve the performance of the site. By staying on our site, you agree to the terms of use of cооkies. To view our Privacy and Cookie Policy, please. click here.